STEM Black History Facts 13/28 Otis Boykin improved electrical components used in pacemakers, increasing the reliability of lifesaving implantable medical devices.

These Famous Black Inventors Probably Changed Your Life. Here’s What to Know About Their Creations.

Madam C.J. Walker, Mark Dean, and Patricia Bath are just a few Black inventors who have made life easier.

biography.com

🎉 LEE LAB PAPER ANNOUNCEMENT for this month's issue of #GENETICS! We're celebrating from both coasts, bc after defending her MS in 2024, Deepshi's now a biotech researcher in the Bay Area. tl;dr: nucleosome remodeling is necessary to repair germline DNA damage 🧬 academic.oup.com/genetics/art...

I think that, like with art, papers offer an opportunity for you to tell the story your own way. Could another person research the same question? Yes. However, each person has the opportunity to do it and communicate it in their own way, and we must protect that 🧪

Let’s make it viral folks. Thank you @histoftech.bsky.social.

Mar Hicks@histoftech.bsky.social · 8mo ago

No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition. Which just makes me want to share it again: www.nature.com/articles/d41...

🧬🔬🎥 @science.org Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries | Science www.science.org/doi/10.1126/...

Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries

Eukaryotic gene expression is orchestrated by RNA polymerases (RNAPI, II, and III) and associated factors, yet their real-time dynamics remain obscure. Using single-molecule tracking in living yeast, ...

science.org

So the question here is mis-specified. There is no "alternative" research funding in any way that would make American biomedical research whole for researchers to seek out. 1/ www.statnews.com/2026/02/03/p... via @statnews.com

We asked whether principal investigators have plans in place for how research can continue without them

Researchers must be mindful of unexpected events that may leave them incapacitated or unable to lead their research projects or labs.

statnews.com

More attention here, please.

Radley Balko@radleybalko.bsky.social · 8mo ago

Floored by this story. A man wrote a pollite email to a federal prosecutor objecting to the deportation of an Afghan seeking asylum. DHS responded with an administrative warrant to get the man's info from Google, then visited his home to intimidate him.

Terrific paper on a new chromosomal compartment where extensive loop extrusion isolates domains from other such domains

The EMBO Journal@embojournal.org · 8mo ago

How do compartmentalization & loop extrusion organize eukaryotic genomes beyond classical model organisms? Hi-C analysis of silkworm chromosomes by Drinnenberg, Muller, Mirny et al reveals new combination of these mechanisms, and a new, secluded “S” compartment link.springer.com/article/10.1...

Unquestionably the result of combined effort from all current and former lab members, support from colleagues @CSU and @CU, and support from @hhmi-science.bsky.social and NIH over decades. A heartfelt 🙏 to my nominators and of course @vilcekfoundation.bsky.social. vilcek.org/prizes/prize...

Karolin Luger - Vilcek Foundation

Karolin Luger's research led to the capture of a high resolution image of chromatin, resulting in the development of innovative drug treatments for diseases like cancer.

vilcek.org

Everyone who tut-tuts co-workers concerned about their job and health insurance should probably include some info on their own household finances, retirement situation and health conditions, current and anticipated.

Jeremy Berg@jeremymberg.bsky.social · 9mo ago

Powerful piece in STAT this morning from some NIH staff members who have resigned www.statnews.com/2026/01/10/n... 1/3

Join our virtual seminar! @sedonamurphy.bsky.social presents cutting-edge research on 3D genome organisation & epigenetic memory in development, moderated by @stefanschoenfelder.bsky.social 📅 Jan 8, 4pm UK 💻 Zoom Register: us02web.zoom.us/webinar/regi... #3DGenome #Epigenetics #ChromatinBiology

Can someone please respond to Stephen Miller with this message from Frank Sinatra?

Sherrilyn Ifill@sifill.bsky.social · 9mo ago

Imagine watching Sinatra, son of Dolly & Antonini born in Genoa & Sicily, respectively, and Martin, son of Gaetano & Angela, born in Montesilvano, Italy & Ohio respectively, (Angela to parents born in Monasterolo, Italy), and crusading against the value of children of immigrants to the U.S.

Please folks. Learn the history.

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists! www.nature.com/articles/s41...

An integrated view of the structure and function of the human 4D nucleome - Nature

The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitatin...

nature.com

@pravrutharaman.bsky.social got super intrigued about EZHIP/CATACOMB, previously identified as a histone H3K27M mimic of PRC2. You can read about her efforts here: www.biorxiv.org/content/10.6... We hope these analyses will help spur more analyses in this very cool gene! 1/

Dynamic evolution of EZHIP, an inhibitor of the Polycomb Repressive Complex 2 in mammals

The Polycomb Repressive Complex 2 (PRC2) is an ancient, conserved chromatin-interacting complex that controls gene expression, facilitating differentiation and cellular identity during development. It...

biorxiv.org

coming up for air after long periods of major depression feels like whiplash. late to the horrible news of our loss of Zara Weinberg. at a loss for words but she was one of the most amazing people i’ve known. brilliant. empathetic. making a huge difference in the world. i will miss her terribly.

Get bedder v0.1.8 and r𝗲𝗮𝗱 𝘁𝗵𝗲 𝗱𝗼𝗰𝘂𝗺𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻 here: github.com/quinlan-lab/... We are looking for researchers to kick the tires, integrate bedder into their pipelines, and provide feedback on the Python functions, performance, and overall user experience! Please share and give us your feedback.

Release Release v0.1.8 · quinlan-lab/bedder-rs

Changes in v0.1.8 Downloads bedder-static-linux-x86_64: Static binary for Linux x86_64 (no dependencies required) bedder-static-macos-x86_64-python3.13: macOS x86_64 binary built with Python 3.13 ...

github.com

We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n

Truly enjoyed writing this piece about recent discoveries by @bloodgenes.bsky.social and colleagues about how we can improve HSC expansion & gene editing by blocking ferroptosis! Our @natcellbio.nature.com N&V: rdcu.be/eR25t Associated article: tinyurl.com/msf9x8fn

Blocking ferroptosis to expand human HSCs

Nature Cell Biology - Haematopoietic stem cells (HSCs) are used in a variety of cellular therapies, but our ability to support these cells ex vivo remains technically challenging. A new study...

rdcu.be

AI is good at needling people, had me in stitches following this thread!

Karolin Luger@nucleosomepolice.bsky.social · 10mo ago

say what now?

the best thing ever is when the person you are writing a letter for makes calendar invites for you for the deadlines

The lab published a nice paper, so we celebrated at our Friday lab meeting 🎉 #Publication #Science #GraduateSchool #BiomedicalSciences #Timeless #Cancer #Research #Senescence

i hate it here. this is awful in so many ways i dont even have the words

Roland Hatzenpichler@environmicrobio.bsky.social · 11mo ago

“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”

Congrats again, everyone

Ashton Pittman@ashtonpittman.bsky.social · 11mo ago

Meanwhile, here's an example of the horrendous things found in Hillary Clinton's emails—the only story worth covering for any serious news outlet in 2016, apparently. This email is also regarding a child who suffered abuse from a grown man.

Had an amazing time at the CSHL Genome Informatics 2025 conference! Presented my poster: “Investigating quiescence-specific roles of FUN30 in chromatin compaction” 🧬 @chrstne.bsky.social #GI2025 #Chromatin #Genomics #Quiescence

This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social Day 13 Prompt DRINK Pdb: 7BTW A pair of mitochondrial outer membrane β-barrel SAM complexes from Saccharomyces cerevisiae, the yeast used to make beer. Cheers! Next: TRUNK Suggestions?

Roughly 900 PIs who will not be getting their award in FY2025. But also they will not have that money for FY2026, FY2027, FY2028 or FY2029. and *next* year, we will be adding some more applicants to this list even if by some miracle the NIH budget is the same.