Sunday at #ANZUP #ASM26 here in beautiful Adelaide starts with the Perfect Pitch, Trial Coordinators Session and ANZUP/PCFA Nurses Session. But first, coffee and thanks to Icon for supporting this essential kick-start! @anzuptrials.bsky.social @iconcancercentre.bsky.social #PCFA
Craig Gedye
@craiggedye.bsky.social
Medical oncologist, physician/scientist #cansky #oncosky #clinicaltrials #kidneycancer #braincancer #prostatecancer #btsm #pcsm #kcsm @anzuptrials.bsky.social @COGNOtrials @iconcancercentre.bsky.social Posts my opinion only. #FCOI http://bit.ly/3xKTdPm
People that confuse correlation with causation need to drink 8 glasses of water per day during hydration breaks xkcd.com/3260/
On World Kidney Cancer Day, it's incredible to reflect what progress has been made, but how much there is still to go. This recent paper shows what we might be possible if every person with advanced #kidneycancer could experience a complete response to immunotherapy www.ejcancer.com/article/S095...
Thank you once again to 347 Australians with #glioblastoma, 28 hospitals, over 70 Consortium members, the NHMRC CTC, and COGNO as we present the MAGMA trial at #ASCO #ASM26
If anyone argues “But what about baseload?” when you talk about renewable energy, please reference this article www.afr.com/policy/energ...
Record heatwave no match for solar-soaked power grid
Energy demand reached its highest level on record on Wednesday during this week’s heatwave, but rooftop solar has taken the stress off.
afr.com
The kids have (sadly) aged out of Lego advent calendars, so thanks again to @FreseniusKabi for shipping their IV saline in such strong and repurposable cardboard boxes!
Grateful to have overheard a colleague talking about "preemptive pregabilin". Offered immediate upfront pregabilin for a patient with florid and painful shingles, with rapid improvement of pain. No prospective trials but interesting case series. 10/10 would Rx again. journals.lww.com/ejanaesthesi...
"Beyond respectful language, which is the minimum requirement… [this study] reinforces the broader message about maintaining respect for patients as individuals & ensuring that this is reflected in our words & deeds." @ascocancer.bsky.social @jco-asco.bsky.social @ethicsdoctorp.bsky.social
Don't Do Me Like That: Promoting Respectful Language in Oncology Research | JCO Oncology Practice
ascopubs.org
Thanks so much to @anzuptrials.bsky.social for helping us starting putting the NZ into ANZUP - great ideas shared on the day for clinical trials for people with GU and prostate cancers in NZ and maybe also AUS as well!
First @anzuptrials.bsky.social Ideas Generation Workshop in New Zealand - putting the NZ into ANZUP! Thanks to Nicky Lawrence and @craiggedye.bsky.social for the warm welcome.
Fantastic to have this critical advice for older people with cancer - thank you @crisbergerot.bsky.social @bogda-koczwara.bsky.social and team
🚨New @ascocancer.bsky.social Guideline Alert! 🌍 Honored to have worked alongside #EnriqueSoto & cols in developing this guideline Check out the latest recommendations on GA, designed to improve care worldwide 📄Full guideline ascopubs.org/doi/pdf/10.1... 🎙️Don’t miss the accompanying podcast!
Online today! *Aging, Immune Fitness and Cancer* 🔬 Learn the latest about the intersection between these processes in @natrevcancer.nature.com 🧬 Great to work with @sandramcallister.bsky.social lab again 😁 doi.org/10.1038/s415...
It’s out!!!!! We hope our review on aging, immunity, and cancer is helpful. Such a rewarding group effort led by Melissa Dolan, with Kendra Libby, Alison Ringle, and @vangalenlab.bsky.social So grateful to @gabriellebrewer.bsky.social @natrevcancer.nature.com for her efforts and support
One more of my votes for the #Hottest100 #TripleJ in the #Hottest200 today... The Whitlams - Blow Up The Pokies www.youtube.com/watch?v=7B49..., still as relevant today www.theguardian.com/australia-ne...
The Whitlams - Blow Up The Pokies (Official Video)
YouTube video by thewhitlamsofficial
youtube.com
Question remains, is the abscopal effect real? Or is #RT just additive? Certainly evidence for modifying TME, intriguing data for WNT-mt patients when adding #radiotherapy to #PD1 #immunotherapy, but the idea of #RT being a 'vaccine', expanding the immune repertoire, is shown in just 1-2 patients.
🚨ARTICLE now published at Nature Cancer ! ✏️By Valsamo Anagnostou and colleagues 'Combination of pembrolizumab and radiotherapy induces systemic antitumor immune responses in immunologically cold non-small cell lung cancer' 🔗 www.nature.com/articles/s43...
The Renal IGW is fast approaching. Concept submissions close in 1 week! Register your attendance here anzup.org.au/idea-generat... @craiggedye.bsky.social
Two opinions that to my surprise are either unpopular or not widely held: 1. The control arm of a randomised trial should be best standard of care. 2. A PFS benefit against an inactive comparator is not a major advance, if progressive disease is required for eligibility.
Great kickoff to clinical trials workshop #ANZUP25 — #MelissaLeMesurier w patient perspective and #ChrisGianacas biostats on collaborative efforts for clinical trials. Same global themes for clinical trial development. @anzuptrials.bsky.social @craiggedye.bsky.social @profiand.bsky.social
Tremendous insights with immediate patient impact; using genomic data we can collect routinely from today's patients, we may be able to predict upfront resistance, rather than subject people to 3-4 cycles of chemo, and we might also be strategic if we know people have sensitive cancers - bravo!
🚨Chemo treatment upgrade!🚨 Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇
Acquired resistance limits the efficacy of cancer treatments & accounts for therapy failure in most patients. Our Roadmap explores how innovative technologies bridge the gap between fundamental research on resistance and clinical translation into actionable strategies www.nature.com/articles/s41...
Acquired resistance in cancer: towards targeted therapeutic strategies - Nature Reviews Cancer
Acquired therapeutic resistance is a key contributor to cancer treatment failure, requiring new approaches to address its complex mechanisms. In this Roadmap, Soragni, Knudsen and colleagues discuss t...
nature.com
Meet Cherrie, one of the earliest participants in the CHALLENGE trial, and my colleague Janette Vardy talking about what these results mean. www.9news.com.au/videos/natio...
9News - Latest news and headlines from Australia and the world
Latest news and headlines from Australia and the world
9news.com.au
Presenting at #ASCO25 today! I was expecting to find evidence that oncologists prefer more-lucrative treatments, and was surprised by our results! Clinical benefit matters, drug profit did not. Cc @dusetzinas.bsky.social
#Teletrials in action: a generous and kind participant called me this week for Visit #3 of his participation in @anzuptrials.bsky.social #ANZadapt #clinicaltrial. “Where are you?”, I asked. “Let me send you a photo”, he said. How’s the serenity…
🚨 Public consultations now open: help shape how medicine information is shared with patients. We are reviewing the template used for EU package leaflets. Have your say on how to make them more understandable and relevant to patients. 🔗 Learn more & share your input: europa.eu/!TCm47q
Excellent, thought-provoking presentation by Deb Maskens of IKCC on the % of patients that are not being reached by #KidneyCancer organisations and strategies to consider on how we can improve. #IKCC25 @debmaskens.bsky.social
Welcome @myesmo.bsky.social!
🚀 ESMO is now on Bluesky This is not an April Fools' announcement, nor is it an AI-generated post. ESMO is launching on Bluesky with a poll on AI to start the conversation. Join us for the latest in oncology education and information. #AIOncology #HealthAI #ESMOAI25
Great piece from Lancet Global Health on democratising clinical trials research to strengthen primary healthcare, relevant to ALL healthcare. Every healthcare intervention is a clinical trial of n = 1; why not learn from every patient, every clinician?
Psych. Science just published a paper showing that the "warm glow" of donations can reduce depressive symptoms (d = [0.19, 0.46]). Most impressively, "micro" donations (one Chinese cent, or $0.0014) appear sufficient to trigger these large effects. Big if true? Let's dive in.