⌛️There is still time to register for #BICC2026 "From Tumour Genesis to Metastasis: an immune perspective" Don't miss out on the chance to hear from our fantastic speakers, including keynotes from Frances Balkwill, John Wherry and Karin de Visser! www.beatsonconference.org/
Cancer Research UK Scotland Institute
@cruk-si.bsky.social
Cancer Research UK Scotland Institute (formerly the CRUK Beatson Institute). Our Mission: Cancer discovery for patient benefit. www.crukscotlandinstitute.ac.uk
Hooke Medal winner Stephen Tait @mitosrus.bsky.social @cruk-si.bsky.social is presented with his medal by BSCB president Laura Machesky before his fantastic medal talk on 'mitochondria, death and something in between' #DynamicCellVI
🆕Paper from Naomi van den Berg (@naomiirisvdberg.bsky.social) in Cancer Cell proposes the "immunometabolic gatekeeping" framework to explain how tissue metabolism conditions tumour immunity @crick.ac.uk @cruk-mi.bsky.social @uofgcancersciences.bsky.social @cp-cancercell.bsky.social
Immunometabolic gatekeeping: How tissue metabolism conditions tumor immunity
Why the link between immune infiltration and tumor control varies so strongly across tissues remains unresolved. We propose the “immunometabolic gatekeeping” framework, whereby tissue-intrinsic metabo...
cell.com
🚨Don't miss out! Early bird registration for #BICC2026 closes 1 April (10am BST) Join global leaders in cancer immunology in Glasgow this June 📍 @cruk-si.bsky.social, Glasgow | 📅 22-25 June #CancerResearch #Immunology 👇Register now👇
Beatson International Cancer Conference 2026
beatsonconference.org
📣Register now for the Beatson International Cancer Conference 2026 ‘From Tumour Genesis to Metastasis: an immune perspective’ 📅22-25 June 2026 📍CRUK Scotland Institute, Glasgow 🎟️Early Bird registration closes on 1 April 🔗 www.beatsonconference.org #BICC2026 #CancerResearch #Immunology
📣Register now for the Beatson International Cancer Conference 2026 ‘From Tumour Genesis to Metastasis: an immune perspective’ 📅22-25 June 2026 📍CRUK Scotland Institute, Glasgow 🎟️Early Bird registration closes on 1 April 🔗 www.beatsonconference.org #BICC2026 #CancerResearch #Immunology
Our Best Models Working Group can offer advice on the use of a range of model systems. The next in our series of #MeetTheExpert posts features Laura Greaves, whose group investigates the role of age-related mitochondrial DNA mutations in cancer biology nmgn.mrc.ukri.org/working-grou...
MAPK-driven epithelial cell plasticity underlies colorectal cancer therapeutic resistance: Members of our Cancer Cluster contributed to a recent paper that provides insight into resistance to therapy and suggests strategies that may improve therapeutic efficacy nmgn.mrc.ukri.org/news/mapk-dr...
MAPK-driven epithelial cell plasticity underlies CRC therapeutic resistance | National Mouse Genetics Network
(White et al., Cancer Research UK Scotland Institute and collaborators across the MRC National Mouse Genetics Network – Cancer Cluster) Colorectal cancer (CRC) is a genetically complex disease, yet re...
nmgn.mrc.ukri.org
My first-author paper is out in @chemicalscience.rsc.org from my time in Professor Danny Huang’s laboratory @cruk-si.bsky.social. We showed that CBL can be used as a degrader E3 to target the “undruggable” eIF4E. pubs.rsc.org/en/content/a...
CBL ubiquitin ligase targets translation as a degrader E3
Proteolysis Targeting Chimeras (PROTACs) are heterobifunctional molecules that recruit an ubiquitin ligase (E3) and a neo-substrate into a ternary complex, enabling selective protein degradation. Desp...
pubs.rsc.org
We are delighted to announce that @mitosrus.bsky.social from @cruk-si.bsky.social @glasgow.ac.uk has been awarded the 2026 Hooke Medal You can read about Stephen's work on mitochondria, cell death and cancer here: bscb.org/hooke-medal-...
📣Research from Owen Sansom's group @cruk-si.bsky.social has suggested a new way to tackle liver and bowel cancers 📖Read the full paper here: www.nature.com/articles/s41...
Scientists discover potential new treatment to tackle cancer
The research focused on the genetic faults that allow the disease to hijack a signalling system in the body.
bbc.co.uk
🆕Paper in @natgenet.nature.com from Georgios Kanellos in Owen Sansom's lab: Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation www.nature.com/articles/s41...
Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation - Nature Genetics
Npm1 promotes tumor formation via attenuating the integrated stress response and p53 activation in mouse WNT-driven intestinal and liver tumorigenesis.
nature.com
Bowel cancer is increasingly diagnosed in young people in Scotland - but what are we doing? Hear about our heroes in lab coats who are seeking answers, Dr Santi Susanti and Dr Johan Vande Voorde👇🥼 @cruk-si.bsky.social @johanvandevoorde.bsky.social @uofgnews.bsky.social youtu.be/if0VzNmlnx8?...
Scotland Tonight Dr Susanti and Dr Johan Vande Voorde on early on set bowel cancer.
YouTube video by Fiona MacLeod
youtu.be
Read the newly published impact report from the SPECIFICANCER team that reshaped our understanding of tissue specificity. Thanks to our co-funders, @themarkfdn.bsky.social, for supporting the #CancerGrandChallenges team and global science. 🔗 lnkd.in/eDrQ9guu
Liver lobule zone molecular characteristics dictate susceptibility to WNT-driven liver cancer 📷 Alexander Raven et al @cruk-si.bsky.social in @nature.com ➡️ bpod.org.uk/archive/2025...
The new paper from SPECIFICANCER, published in @natureportfolio.nature.com reveals that it’s not just the mutation that matters — it’s where in the liver that mutation appears. Congratulations to the team (co-funded by @themarkfdn.bsky.social). 👉 Read more: lnkd.in/eTVh9YY6
⌛Just one week left to submit your applications for the Black Leaders in Cancer PhD programme in Scotland!
PhD Studentships
crukscotlandcentre.ac.uk
📢 Applications for the Black Leaders in Cancer PhD programme in Scotland are now open! The programme offers a unique opportunity for students from Black heritage backgrounds to pursue a fully funded 4-year PhD. 👉Apply by 24 November 2025: www.crukscotlandcentre.ac.uk/training/phd-studentships
Less than 3 weeks left to submit an abstract to the PREDICT-Meso International Conference 2026 in Glasgow Categories: CLINICAL STUDIES&PATIENT CARE TARGETS MODELS&THERAPIES RISK&RESPONSE Submit abstracts online eventsforce.net/predict_meso... by 30 Nov 2025 #Mesothelioma #MesotheliomaConference
eventsforce.net
Excited to share our latest work in collaboration with the @edreznik.bsky.social lab @mskcancercenter.bsky.social, where we describe functionally dominant mitochondrial DNA mutations in patient tumors. So, what is functional dominance in mitochondrial genetics, I hear you ask? rdcu.be/eN1jm
Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer
Nature Genetics - Analysis of 14,106 tumor genomes highlights recurrent mutations in mitochondrial ribosomal RNA encoded within the mitochondrial genome. Mutations occur at hotspot positions and...
rdcu.be
📢 Applications for the Black Leaders in Cancer PhD programme in Scotland are now open! The programme offers a unique opportunity for students from Black heritage backgrounds to pursue a fully funded 4-year PhD. 👉Apply by 24 November 2025: www.crukscotlandcentre.ac.uk/training/phd-studentships
🩷Thanks to everyone from @cruk-si.bsky.social and @uofgcancersciences.bsky.social who took part in our #WearItPink day today raising money for @breastcancernow.bsky.social 🩷
👏 Congrats to Ridvan Nepravishta and Kenneth Cameron at @cruk-si.bsky.social on their paper in #JACS: Fast and reliable NMR-based fragment scoring for drug discovery bit.ly/43LfgYa #OnMyHorizon @pubs.acs.org @csic.es @edinburgh-uni.bsky.social @rnepravishta.bsky.social @angulo-lab.bsky.social
Undergraduates, we are recruiting! Come and join us at the @cruk-si.bsky.social in Glasgow for your industrial placement year. Start date September 2026. Great lab, great people, great city. Take a look! cancerresearchuk.wd3.myworkdayjobs.com/en-US/Extern...
Biosciences Student Placement (Lab based)
Cancer Research Horizons Biosciences Student Placement (Lab based) £23,000 plus benefits Directorate: Research & Innovation Contract: Fixed Term Contract 52 weeks Hours: Full time 35 hours per wee...
cancerresearchuk.wd3.myworkdayjobs.com
Are you interested in becoming a clinical academic leader in a cancer-focused discipline? @edinburgh-uni.bsky.social, @uofglasgow.bsky.social, @cruk-si.bsky.social & Cancer Research UK Scotland Centre are seeking four ambitious people for the TRACC+ Programme August 2026 intake 👉 edin.ac/4nGK5oC
🎉Good news! The deadline for abstract submissions has been extended! You now have until Friday 3 October to submit your abstract for the @cruk-si.bsky.social Workshop: 'Lessons from the Microbes Within Us; Developing Next Generation Immunotherapeutics'
Lessons from the microbes within us; developing next generation immunotherapeutics
crukscotlandinstitute.ac.uk
🔬Join us for our upcoming Cancer Immunology Workshop: 'Lessons from the Microbes Within Us; Developing Next Generation Immunotherapeutics' 📅23-24 October 2025 📍CRUK Scotland Institute, Glasgow Abstract deadline: 26 September Register by: 10 October crukscotlandinstitute.ac.uk/immuno_works...
Our first session of today's #OrganoidsAreUs2025 is dedicated to organoid models in cancer research. We go with ✨ Vincenzo Corbo ✨ Ben Dwyer ✨ Maximilian Reichert ✨ Chiara Braconi Another packed session for a critical and fast-developing field!
Exciting news - we are recruiting new Group Leaders! 🥼 We are seeking to appoint exceptional early-career scientists & clinician scientists as #GroupLeaders to develop bold, innovative, high-impact #CancerResearch programmes Full details on our website: www.cruk.manchester.ac.uk/career/new-g...
Group Leader Recruitment at the Cancer Research UK Manchester Institute
YouTube video by CRUK Manchester Institute
youtu.be
Second session on #StemCells #regeneration and #cancer. We start with 🧪 Phil Jones from the @sangerinstitute.bsky.social 🧪 Followed by Suet Yu Leung from Hong Kong Uni and 🧪 Eleanor Earp from @edinburghuni.bsky.social , ✨ First keynote lecture by Helmuth Gehart from @ethz.ch #OrganoidsAreUs2025
A day dedicated to #StemCells #regeneration and #cancer. 1st session sponsored by TECAN with Nick Barker from A*STAR, Amian Barai from @univ-amu.fr and our first Tony Burgess Orator, Vivian Li from @crick.ac.uk, providing a fascinating insight into this fast-developing area #OrganoidsAreUs2025