Dina Grohmann
@curiousdina.bsky.social
Curious scientist and fan of single molecules, RNA and Archaea
Decoding extremophiles: insights from bioinformatics, machine learning, and data-driven approaches #microbiology #extremophiles #bioinformatics #MicroSky doi.org/10.1093/bib/...
Decoding extremophiles: insights from bioinformatics, machine learning, and data-driven approaches
Abstract. Life thrives in Earth’s most inhospitable environments, from boiling hydrothermal vents to hypersaline lakes and frozen polar deserts, thanks to
doi.org
With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...
DefensePredictor: A machine learning model to discover prokaryotic immune systems #microbiology #prokaryotes #CRISPR #MicroSky @science.org www.science.org/doi/10.1126/...
DefensePredictor: A machine learning model to discover prokaryotic immune systems
Antiphage defense systems protect bacteria from viral infection and have inspired important biotechnologies such as CRISPR-Cas9 while also revealing the evolutionary roots of eukaryotic innate immunit...
science.org
🧬 Last call to join us in Cambridge for #EMBOMBoA26 (July 6th-10th)! We are just one week away from the registration and abstract submission deadline for the EMBO Workshop on the Molecular Biology of Archaea!
2nd call for postdoc positions in the lab. Get in touch for more information or simply apply here: mbg.au.dk/en/news-and-...
Postdoc positions in Nuclear RNA Biology - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University
mbg.au.dk
Poster abstracts and early bird registrations for the 31st Annual Meeting of the RNA Society are due by March 31st! RNA 2026 website: rnasociety.org/conferences/ #RNA26
This is a moment to pause—with deep gratitude and a touch of humility—to share some exciting news: I’ve been elected as a Fellow of the European Academy of Microbiology (EAM). fems-microbiology.org/european-aca... [some words of thanks and thoughts in the comments]
European Academy of Microbiology welcomes 95 new Fellows
Discover the latest election of 95 new Fellows by the European Academy of Microbiology, highlighting diverse expertise in the field.
fems-microbiology.org
We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).
We are excited to share our new preprint: iCLIP3 — an improved protocol for transcriptome-wide mapping of protein–RNA interactions at single-nucleotide resolution.
bioRxivpreprint@biorxivpreprint.bsky.social · 5mo agoiCLIP3: A streamlined, non-radioactive protocol for mapping protein-RNA interactions in cellular transcripts at single-nucleotide resolution https://www.biorxiv.org/content/10.64898/2026.03.01.708747v1
If you love RNA and RNA machineries as much as we do at @uniregensburg.bsky.social we encourage young scientists who want to start their own lab to apply.
@meisterlab.bsky.social · 5mo agoExciting news: Our RNA community in @uniregensburg.bsky.social is set to grow! We are opening a Junior Group Leader position in RNA biochemistry / ribonucleases / RNA stability. A great opportunity to start your own team within our collaborative RNA network. Details & application 👇
A new preprint from the @archaeon-alex.bsky.social and Joey Davis (MIT) labs! We solved the structure of the ribosome from the archaeon Haloferax volcanii and discovered a new highly conserved ribosome hibernation factor that we named AHA (AMPKγ–HPF from Archaea) 🧵⬇️ www.biorxiv.org/content/10.6...
biorxiv.org
If you are looking for “more”, apply for this outstanding PhD program which offers you ample opportunities to develop as a scientist and leader connecting to peers, leaders in the RNA field in Germany, Europe and around the world. Learn the science but also about translation into applications.
Jörg Vogel@jorg-vogel-lab.bsky.social · 5mo agoLooking for a truly unique PhD programme on RNA drugs and therapeutics? We have just opened the call for the second cohort of RNAmed-Future leaders in RNA-based medicine. More details under www.rnamed.de Please spread the word.
In terms of key literature, I use this protist symbiosis review paper all the time! www.cell.com/current-biol... and for rRNA database, PR2 and SILVA
Bacterial and archaeal symbioses with protists
Symbiosis is a major source of evolutionary innovation, but our understanding of it mainly comes from animal systems. Husnik et al. review symbioses involving protists, the microbial cells that repres...
cell.com
We are happy to share our newest preprint on a novel strain of Ca. Lokiarchaeum ossiferum, that contains an active provirus, capable of excision and independent replication! We propose a novel virus family: Fylgjaviridae. www.biorxiv.org/content/10.6...
biorxiv.org
New paper from my group in @science.org : "A small polymerase ribozyme that can synthesise itself and its complementary strand" www.science.org/doi/10.1126/... Outstanding work by @edogia.bsky.social
With these authors you know it’s a must-read
César Sánchez@twistedbacteria.bsky.social · 6mo agoThe immune systems paradox Some widespread prokaryotic immune systems are absent in eukaryotes, whereas relatively rare ones became central to eukaryotic innate immunity @audeber.bsky.social & E. Koonin hypothesize the answer is #HGT shareable link: rdcu.be/e2EmD www.nature.com/articles/s41...
Archaea , archaea everywhere ☺️!
Guillaume Méric@gmeric.bsky.social · 6mo agoMore and more cool work looks at the role of human archaea in health outcomes. In this preprint, authors suggest protective role & show that colonisation of mice with M. smithii or M. stadtmanae thickens mucus, boosts reg. T cells & protects vs DSS colitis. www.biorxiv.org/content/10.6...
Always a pleasure to work with the @archaellum.bsky.social lab - diving into the regulation of cell motility & shape in Haloferax this time. On our side, @felixgrunberger.bsky.social was the RNAseq guru again. Shoutout also to Anita Marchfelder (giving a posttranscriptional twist to the story).
Sonja-Verena Albers@archaellum.bsky.social · 6mo agoThis work started as a bachelor project and @1nussi1.bsky.social and @felixgrunberger.bsky.social showed that CsmR is a very interesting regulator important for controlling motiliy and cellshape in Haloferax volcanii. The preprint is out now: www.biorxiv.org/content/10.6...
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social. 📄 www.science.org/doi/10.1126/... 🌐 search.foldseek.com/foldmason 💾 github.com/steineggerla...
Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
science.org
Excited to share our latest preprint: "SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications" www.biorxiv.org/content/10.6... Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6
biorxiv.org
Just out @natrevimmunol.nature.com RNA-binding proteins and ribonucleoproteins as determinants of immunity www.nature.com/articles/s41... gives our perspective on this growing area of research. Special thanks to the editor Alexandra, for streamlining the manuscript.
RNA-binding proteins and ribonucleoproteins as determinants of immunity - Nature Reviews Immunology
RNA-binding proteins (RBPs) considerably expand the information content of the genome and can determine the lifespan, localization and function of RNA, thereby controlling when, where and how much pro...
nature.com
Important point by @evgenii-protasov.bsky.social ! Same applies for the recent taxonomic changes in the archaeal domain of life.
Evgenii Protasov@evgenii-protasov.bsky.social · 6mo agoWhy rename Pseudomonas putida KT2440 to P. alloputida🦠? This is an excellent example of why taxonomic changes require caution. We shouldn't blindly follow rules while ignoring decades of established practice. journals.asm.org/doi/10.1128/... #microbiology @asm.org @microbiologysociety.org
SAVE THE DATE! The next instalment of the long-running Bacterial and Archaeal Cell Division Conference will take place at www.marriott.com/en-us/hotels..., Italy from the 20th to 23rd of April 2027. Organisers: me, @s-lab.bsky.social, @awehenkel.bsky.social. More info soon. #MicroSky
marriott.com
I am a big admirer of Joan Steitz and her amazing work! Admirable scientist indeed!
Admirable Women@admirablewomen.bsky.social · 6mo agoBiochemist/molecular biologist Joan Steitz was born #OTD in 1941. She (& team) figured out how our cells read/use genetic instructions to make proteins. A key person who helped crack the code on RNA—the molecule that acts like a messenger between DNA & and the proteins our bodies need. #WomenInSTEM
Such a thoughtful and thought-provoking article. Excellent Sunday read. Especially today. Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2026/01/25/o...
Opinion | It’s So Hard Not to Be Consumed by Rage
nytimes.com
new paper from the Lai lab! Renfu Shang performs careful mechanistic dissection of miRNA cluster assistance and reveals many insights and surprises to this enigmatic regulatory strategy that gives suboptimal miRNAs a boost. if you love Northerns, you'll ♥️ this! 🧬 genesdev.cshlp.org/content/earl...
Separable roles for Microprocessor and its cofactors, ERH and SAFB1/2, during microRNA cluster assistance
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
Our latest CRISPR ring nuclease paper focusses on Csx15 - which seems to act as of a sponge as well as a canonical phosphodiesterase. Great work led by @haotianchi.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
