Opinion @cp-trendsimmuno.bsky.social @sjturn.bsky.social Targeting the fate of exhausted CD8+ T cells www.sciencedirect.com/science/arti...

Had a lot of fun writing this review @cp-trendsimmuno.bsky.social with @sjturn.bsky.social

Steve Turner@sjturn.bsky.social · 5d ago

What is T cell exhaustion? Good question! For some answers, feel free to read our recent review out in @cp-trendsimmuno.bsky.social. Co-authored with @danielutzschneider.bsky.social who made writing this review a great learning experience and a lot of fun. www.sciencedirect.com/science/arti...

Online now: B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection

B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection

Extrinsic factors that support CD8+ T cell responses during chronic viral infection are incompletely defined. Gago da Graça et al. identify a crucial role for B cells in triggering type I interferon production, thereby promoting T cell effector formation in response to high antigen exposure, as seen in chronic infection.

dlvr.it

New research from Peter Mac has uncovered further evidence of how pregnancy triggers a powerful, long-lasting immune response in the breast, opening the door to potential new ways to prevent #breastcancer in people at high risk. Read more: petermac.org/about-us/new...

Pregnancy-induced tissue-resident memory-like T cells contribute to tumor control in breast cancer www.nature.com/articles/s41... @natimmunol.nature.com @petermaccc.bsky.social

Great to share our recent review, written with @niclag.bsky.social and @danielthiele1.bsky.social @monashuniversity.bsky.social #monashBDI The evolving biology of T cell memory: A dynamic continuum of function and persistence | Science Immunology www.science.org/eprint/95PIC...

The evolving biology of T cell memory: A dynamic continuum of function and persistence

Advances in technology continue to refine our understanding of CD8 T cell memory, with major implications for next-generation vaccines and therapies.

science.org

I’m excited to share our latest study, published today in @natimmunol.nature.com. It is long known that pregnancy reduces the risk of developing breast cancer, yet the biological mechanisms underlying this protection have remained largely unknown. Read the paper here: www.nature.com/articles/s41...

Pregnancy-induced tissue-resident memory-like T cells contribute to tumor control in breast cancer - Nature Immunology

Here the authors identify an abundance of a tissue-resident memory-like T cell population in the breasts of women who have given birth. These cells can contribute to tumor control and may thereby prov...

nature.com

B cells trigger type I IFN production to promote T cell effector formation in response to high antigen exposure during chronic infection @cp-immunity.bsky.social @thedohertyinst.bsky.social @danielutzschneider.bsky.social @yannick-alexandre.bsky.social www.cell.com/immunity/ful...

Thrilled to share our newest study led by @categraca.bsky.social and @yannick-alexandre.bsky.social published in @cp-immunity.bsky.social Here, we identify B cells as critical helpers for T cells to obtain effector function through enhancing IFN-I 😳 url.au.m.mimecastprotect.com/s/NE67C6X1Py...

B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection

B cells are highly abundant lymphocytes and central players in humoral immunity. Although T cells are well known to support humoral responses, how B c…

url.au.m.mimecastprotect.com

Doherty Institute@thedohertyinst.bsky.social · last mo.

New research reveals B cells do much more than produce antibodies - they also help activate and sustain T cells to fight chronic infections, like cancer or auto immune diseases. https://bit.ly/4wdXKrw

Got to love a good #Tpex viewpoint!

Nature Reviews Immunology@natrevimmunol.nature.com · last mo.

New insights into progenitor exhausted T cell populations

Do you like beach, summer, Greek food AND T cells??? Then please join us for the 1st Aegean conference on T cells in health and disease aegeanconferences.org/conferences/... Registration closes soon (June 15th)!!!

TCF1 is a master regulator of T cell stemness – but can it make exhausted cells go backwards? We setup a CRISPR KI system to ask this question, and the answer was unexpected. www.nature.com/articles/s41...

Ever wondered why gamma delta T cells are required for immunity to liver-stage malaria? www.nature.com/articles/s41...

γδ T cell-derived IL-4 initiates CD8+ T cell immunity - Nature Immunology

The authors show how Vγ1+ γδ T cells produce IL-4 to drive early CD8+ T cell and dendritic cell responses to malaria infection in mice.

nature.com

Right now, the Government is starving medical research of full funding, even as it claims that science and research are national priorities. If our leaders truly value science as much as they say, then they must back their words with action—and fund it properly. Join the campaign!

Medical Research Matters

moniqueryan.com.au

Thanks to funding through the NHMRC's 2025 Synergy and Ideas grants, 27 UniMelb projects have secured $52 million to help turn bold ideas into meaningful impact. Congratulations to everyone involved 👏 Tap through to read more → unimelb.me/4b6xNms

Looking forward to @categraca.bsky.social presenting our recent work. Tune in!

Open Box Science @openboxscience.bsky.social · 7mo ago

Built for Uncertainty: How CD8 T cells Prepare for Acute & Chronic Infection 🎙️ OBS Speaker Highlight 🔬Catarina Gago da Graça @categraca.bsky.social 📢 Paper in @sciimmunology.bsky.social (2025) 📅 Jan 15, 2026 | ⏰5pm ET/ 4pm CT/ 2pm PT 📌 Register here: us02web.zoom.us/meeting/regi...

Online now: Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma

‼️Deadline approaching - Don't miss your chance to submit an oral abstract for 16th Annual Lorne Infection & Immunity Conference 📍Held 18-20 of February 2026 at the Mantra Lorne 📝 Career Development Awards also available Apply at www.lorneinfectionimmunity.org Deadline: Friday, 10th of October

www.theage.com.au/politics/fed...

Billions going unspent from Australia’s $24b medical research fund

Costings commissioned by independent MP Monique Ryan reveal the government could double how much funding it gives to innovative health research each year.

theage.com.au

CSH Asia meeting on Immune Tolerance #CSHA

TGFβ-driven, HOBIT-dependent tissue-residency programs promote tumor-infiltration of CD8 T cells, but disruption of TGFβ in these tumor-infiltrating cells enhances tumor control @natimmunol.nature.com www.nature.com/articles/s41... www.nature.com/articles/s41...

Congrats @yannick-alexandre.bsky.social and team. Great study

Yannick Alexandre@yannick-alexandre.bsky.social · last yr.

I’m pleased to share my latest work, published in Science Advances. In this study, we investigated how fibroblastic reticular cells (FRCs) that populate the white pulp of the spleen regulate immune responses to viral infections. #immunology #immunosky www.science.org/doi/10.1126/...

We're looking for an experienced lab manager to join our wonderful team investigating fundamental T cell biology 🤓 careers.pageuppeople.com/513/cw/en/jo...

Great meeting to (be) lock(ed) in!

Ashraful Haque@assocprofashhaque.bsky.social · last yr.

Register TODAY: Melbourne Immunotherapy Network, 2-day Spring Symposium, Pentridge Prison, Coburg! 2-3 Sept '25. Student Early Bird: $250, inc. conference dinner (No metal prison trays, I promise!) Click below to register and submit your Abstract. www.melbourneimmunotherapy.org/registration

We are recruiting a group leader in laboratory research at Peter Mac Cancer Centre in Melbourne, Australia 🔬🦘💥 Work in a cutting edge research environment in a vibrant world city! We value research excellence, creativity and diversity. Join us! careers.petermac.org/job/MELBOURN...

Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives. An assault on science anywhere is an assault on science everywhere; the global community must unite 🧪 www.nature.com/articles/d41...

Trump 2.0: an assault on science anywhere is an assault on science everywhere

US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.

nature.com

Check out our new paper!

Nicole La Gruta@niclag.bsky.social · last yr.

Our paper is out! LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity | Science Immunology www.science.org/doi/10.1126/...

In the media over the weekend, groundbreaking research from Peter Mac & The Doherty has uncovered a new way to enhance the immune system’s ability to fight cancer. Work at Peter Mac led by @JohnstoneRicky and Dane Newman. More via @australian or here: www.petermac.org/about-us/new...

Very excited about this collaborative study between @petermaccc.bsky.social @danielutzschneider.bsky.social and Kallies lab

Daniel Utzschneider@danielutzschneider.bsky.social · 2y ago

Excited for our lab's FIRST paper #ScienceImmunology! 🎉 Led by @categraca.bsky.social & Amania Sheikh, with amazing collabs from Axel Kallies, Dane Newman, & @rickyjohnstone.bsky.social Huge thanks to reviewers & @claireolingy.bsky.social 🙌 #Tpex #onthescoreboard www.science.org/doi/full/10....