Reach out if you have questions about JCS! The journal has a long history of publishing outstanding science and supporting the research community.

Journal of Cell Science@jcellsci.bsky.social · 4w ago

Working on stem cell biology? Our expert Academic Editor, Aryeh Warmflash (@warmflashlab.bsky.social), handles articles on this topic so send your article our way. It's FREE to publish in JCS and we're not-for-profit. Find out more: journals.biologists.com/jcs/pages/re... #stemcells #ISSCR2026

New preprint! We show that cell fate can be predicted from a snapshot of combinatorial signaling — and the underlying map is a single angle in signaling space. Work by first authors Bassit Fijabi and Seth Teague and collaboration with @davidbrueckner.bsky.social. www.biorxiv.org/content/10.6...

My lab is hiring! We have an open postdoc position to study the endometrial-embryo interface using organoids, embryo models, and live imaging. Reach out or apply: bit.ly/4duGA0P

Read the Research Article 'Dependence of cell fate potential and cadherin switching on the coordinate within the primitive streak during differentiation of human pluripotent stem cells' here. journals.biologists.com/dev/article/...

Primitive streak cells retain broad fate potential uncoupled from cadherin switching This Research Highlight showcases work by Ye Zhu and Aryeh Warmflash. journals.biologists.com/dev/article/...

Send us your stem cell manuscripts! Very easy to transfer from biorxiv and we can also quickly consider a manuscript based on reviews received elsewhere. JCS does a tremendous job of supporting the scientific community (see the link below). Reach out if you have questions!

Journal of Cell Science@jcellsci.bsky.social · 6mo ago

Are you working on stem cell biology? Our Academic Editor Aryeh Warmflash (@warmflashlab.bsky.social) is committed to handling articles on this topic so send your article our way. There are lots of reasons to choose JCS – find out more: journals.biologists.com/jcs/pages/re... #stemcells

Feb 1 deadline approaching for our @kitp-ucsb.bsky.social QBio summer course on Physical Principles of Morphogenesis in Plants and Animals. @streichan.bsky.social @maurazimmermann.bsky.social @maizel-lab.org @yusuke-mori.bsky.social @akankshi.bsky.social @nicolettapetridou.bsky.social

As stressful as it is to run a laboratory in the US right now, my thoughts are often with the NIH staff living in the awful chaos trying to preserve the whole enterprise. I’m grateful for every moment they choose not to give up. These people are the only thing keeping it from entirely collapsing.

Happy to share our latest preprint. We show that juxtaposing amnion cells with human pluripotent cells is enough to trigger gastrulation-like events. Great work by former student Xiangyu Kong now a postdoc in the Theunissen lab @washumedicine.bsky.social www.biorxiv.org/content/10.1...

Juxtaposition of human pluripotent stem cells with amnion-like cells is sufficient to trigger primitive streak formation

Studies in the mouse have established that communication between the trophectoderm and the epiblast is crucial for initiating gastrulation. In the primate embryo, the amnion rather than the trophectod...

biorxiv.org

The "Big Beautiful Bill" isn’t the federal budget—it’s a reconciliation bill focused on tax cuts. The real FY26 funding decisions for NIH, NSF, and more are happening now in Congress. www.ascb.org/science-poli...

If one of these people is your senator, it is incredibly important that you call them today. Urge them to vote NO on the Senate budget bill that would make most Americans poorer to give billionaires a tax cut they don't even need.

Today, my NIH colleagues and I did something scary but really important. We spoke up about egregious harms we are seeing happen to research participants and public health through thoughtless and politicized policies at NIH. 🧵1/3 apnews.com/article/nih-...

NEW: The Trump administration cut research funding that sought cures for future pandemics, examined the causes of dementia and tried to prevent HIV transmission. ProPublica heard from more than 150 researchers to understand the work that’s been lost.

Shattered Science: The Research Lost as Trump Targets NIH Funding

The Trump administration cut research funding that sought cures for future pandemics, examined the causes of dementia and tried to prevent HIV transmission. More than 150 researchers shared with…

projects.propublica.org

Happy to share our latest on a system to study anterior-posterior patterning of the nervous system. We show Wnt signaling pattern is not a simple low to high gradient and timing of activation is crucial to setting the pattern. From outstanding grad student Siqi Du. www.biorxiv.org/content/10.1...

A novel self-organizing embryonic stem cell system reveals the role of Wnt signaling parameters in anterior-posterior patterning of the nervous system

A Wnt activity gradient is essential for the formation of the anterior-posterior (AP) axis in all vertebrates. The relationship between the dynamics of Wnt signaling and specification of AP coordinate...

biorxiv.org

A Path Forward to Save American Bio-Medical Research talkingpointsmemo.com/edblog/a-pat...

A Path Forward to Save American Bio-Medical Research

Over the past four months I’ve spoken to dozens of biomedical researchers...

talkingpointsmemo.com

Our work on mesoderm development in 2D gastruloids is now published in nature methods www.nature.com/articles/s41...

Extended culture of 2D gastruloids to model human mesoderm development - Nature Methods

This study reports an extended 2D gastruloid system for spatially modeling human mesoderm development.

nature.com

Many people are asking - what on earth is the point of killing biomedical research? Read this from @joshtpm.bsky.social who has covered this very well. Admin is using funding to exert control over universities, they don't care about resulting damage to science. talkingpointsmemo.com/edblog/why-d...

Why Do They Have It In For Biomedical Research?

Here is a brief follow-up on the question TPM Reader MA addresses...

talkingpointsmemo.com

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

the word alert is in a purple circle

ALT: the word alert is in a purple circle

media.tenor.com

I received this letter, sent to 11 Republican members of Congress this weekend from anonymous NIHers. 1/n .

As someone directly affected by this, let me be clear: I'd rather lose my job because Harvard chose to fight than keep my job and see a generation of white supremacists parade its corpse around like a war trophy.

STAT@statnews.com · last yr.

Researchers at Harvard and its affiliates appreciate that the university resisted the Trump Administration's demands, but worry about what happens next.

This is a big deal. Spread the word. But it’s tiny compared to the totality of what’s happening at NIH. Cure Research for all cancers, Alzheimer’s, everything is being gutted. Intentionally. It’s all getting burned to the ground but the news isn’t getting out. The new cures won’t be there for you.

Susan Rinkunas@susanrinkunas.com · last yr.

I would be making a big deal out of this if I were an elected Democrat

From a source at NIH: “Right now NIH’s ability to buy things is dead. Nearly all people with the power to make an order — purchasing people — have been removed. The NIH hospital can’t buy medicines, the labs can’t buy petri dishes. X-Ray machine breaks? Too bad. Everything is stopped”

It’s stunning to me that the New York Times did not put the story on the bloodbath at the NIH, CDC, and FDA on its front page this morning.

Trump has cut the NIH budget by more than half in defiance of Congressionally mandated appropriations for the agency. No comparison historically, not even the Great Recession. This is clearly not legal and Congress needs to address it.

"The consolidation/RIF plan pulls power away from scientists and puts it in the hands of political employees. It sets up Trump and Musk to kill NIH as an evidence-based science funder. We must stop this plan." New contributed post on our blog: Please read. It describes Orban and authoritarianism. 🧪

The NIH firing plan is really a radical institute merger and an authoritarian takeover

this is an Orbanization of US science: a move to exert political control over discovery, which will kill the US medical research industry and end cancer cures. The plan must be stopped. We can act.

open.substack.com

Just before bedtime last night I got a message from inside NIH which read: “It’s so, so bad and no one cares (who has any influence)” I asked “What, in particular?” My friend responded “Everything”

The @standupforscience.bsky.social DC rally is on. What we are hearing from around the country: "this is big!" "biggest rally I have seen around here in years and years" The public cares about medical research--and students, GenZ, and other people too are ready to stand up.

Good crowd to #StandUpForScience on Rice campus. Some powerful speeches from trainees about having opportunities suddenly taken from them and the personal impacts of the administration's targeting of minorities. Very real damage has already been done.

Richest guy in the world telling us we can’t afford to have our government fund cancer research.