I'd vote for the future where there's the option of a box that pops up when lazy nonsense appears and says "this looks like AI slop. Would you like me to find a piece written by a thoughtful human on this topic - something that's valued by other humans and is actually worth reading?"

Preprint🚨: Exopolysaccharide export complex PelBC of Pseudomonas aeruginosa attenuates the dynamics of the surrounding outer membrane. Longer in preparation than in actual making. Blame summer time and perfectionism 🫠 A brief tour, to keep the feed alive over the wknd www.biorxiv.org/content/10.6...

This is a great opportunity to present your work! Please send your abstracts to secure a spot. 🤩 Anything in computational structural biology fits the remit.

Australian BioCommons@ausbiocommons.bsky.social · 2mo ago

Calling all #EMCR in #StructuralBiology The ASBC is inviting Australian EMCRs to share their work at a special edition of their quarterly community meeting on 4 November 2026 @kmichie.bsky.social Find out more 🔗

Calling all #EMCR in #StructuralBiology The ASBC is inviting Australian EMCRs to share their work at a special edition of their quarterly community meeting on 4 November 2026 @kmichie.bsky.social Find out more 🔗

Invitation to present your structural biology research — Australian BioCommons

The Australian Structural Biology Computing Community is seeking Australian EMCR researchers in structural biology to share their work at a special online meeting.

biocommons.org.au

So, @arc-gov-au.bsky.social: Why would the UK want to do this? Could it be that much shorter grant processing times are … a good thing? Could there be a competitive disadvantage in taking 4.8 times longer to process grants? What do you think, Minister @jasonclaremp.bsky.social?

The UK government’s research grant agency wants to cut grant processing times from 195 days to 90. Meanwhile, the Australian equivalent, has increased it from 195 days to at least 435 (DP26 vs. DP27). This is for comparable, “applicant led grants”. Make it make sense.

UKRI pledges to cut grant processing time in half - Research Professional News

Funder’s new five-year strategy aims to boost national priority fields, while backing curiosity-driven research

researchprofessionalnews.com

Read our new paper! We show how the protease BepA binds the BAM complex and undergoes striking conformational changes, embedding its water-soluble lid into the membrane to cleave outer membrane proteins. www.nature.com/articles/s41... #cryoEM #astburycentre

Had an amazing day at the @Sydney_Uni, presenting our work at the SABA BacChats Seminar Series! Great scientific discussions throughout the day. Thanks again for the warm hospitality, I thoroughly enjoyed the visit! @doylemt1.bsky.social and @BilgeErcan, thank you both for everything.

This amazing work by @danialv.bsky.social and Bodan Hu is now out in peer-reviewed form at @cp-cell.bsky.social with a lot of new simulations! Check it out if interested in lipid transport!

Vanni Lab at UNIFR, Switzerland@labvanni.bsky.social · 9mo ago

Happy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7) www.biorxiv.org/content/10.6...

Some very cool simulations, look at those little guys climb that ladder! #MolecularNodes

@corrylab.bsky.social · 4mo ago

Excited to share this paper from @yiechanglin.bsky.social showing how lipids can move between bacterial membranes along the bridge like protein TamB. Also happy to be able to post the cool movie. 🎥🌟 #MDsimulations #StructuralBiology doi.org/10.1016/j.bp...

why would anyone vote ON, we would end up like the USA: ruled by incompetents, politicians lining their pockets, grifting for mega billionaires, cost of living skyrockets, science and facts ignored to detriment of health and community. If you cant vote labour or lib vote green or independent

Excited to share this paper from @yiechanglin.bsky.social showing how lipids can move between bacterial membranes along the bridge like protein TamB. Also happy to be able to post the cool movie. 🎥🌟 #MDsimulations #StructuralBiology doi.org/10.1016/j.bp...

This has been a long journey and it's exiting to see our story about the Atg2-18 lipid transfer complex, headed by Sabrina Chumpen, published in @embojournal.org! Great teamwork of the labs @arnemoeller.bsky.social, Stefano Vanni, Fulvio Reggiori and Christian Ungermann! #cryoEM #autophagy #membrane

The EMBO Journal@embojournal.org · 5mo ago

Atg18 interaction positions Atg2 for efficient lipid transfer into phagophore elongation Sabrina Chumpen Ramirez, @dmitryshvarev.bsky.social  et al link.springer.com/article/10.1...

Static vs. cidal: it’s not complex; it’s simply incorrect @bradspellberg.bsky.social et Al Honored to be part of this amazing group who challenges dogmas and debunk ID myths #idsky #microsky journals.asm.org/doi/10.1128/...

What a fascinating story is hiding in bioRxiv!! An elaborate work of @doylemt1.bsky.social an co-workers to understand the function of the bacterial TAM machinery ❤️‍🔥 and here it is, a rich body of evidence for the "ancient" bridge for the lipid transfer 👇 www.biorxiv.org/content/10.6...

Join us on campus on Thursday, 26 March 2026 at 1pm for a seminar by Dr Matthew Doyle @doylemt1.bsky.social, Senior Lecturer from the Faculty of Medicine and Health, The University of Sydney. Details: rb.gy/4uw4uz

And now published as an Observation! Many congrats to @weeboont.bsky.social for discovering that AsmA superfamily proteins, YhdP/TamB/YdbH, localize to the cell poles in E. coli, curiously AFTER division has occurred! 1/3 #MicroSky journals.asm.org/doi/10.1128/...

Polar localization of putative phospholipid transporters in Escherichia coli | mBio

The outer membrane (OM) of Gram-negative bacteria serves as an effective permeability barrier and confers intrinsic antibiotic resistance. This barrier function requires distinct distribution of lipid...

journals.asm.org

Shu-Sin Chng@figlegend.bsky.social · last yr.

@weeboont.bsky.social talked about our lab's recent preprint where we report AsmA superfamily proteins, believed to be phospholipid transporters, localizing to cell poles in E. coli. Really interesting observations, with impt implications for OM assembly! Read it 👇! www.biorxiv.org/content/10.1...

My predictions are that grant delays have a much more severe impact on Australia's productivity than any real foreign interference enabled by any ARC grants.... maybe the delay was always the intended interference.

Danny Kingsley@dannykay68.bsky.social · 8mo ago

DELAY: the work associated with protecting Australian research from foreign interference are causing hold ups and issues for grant applications. www.timeshighereducation.com/news/grant-d... “The requirements we now have to go through…are more extensive and time-consuming than we had imagined,”

DELAY: the work associated with protecting Australian research from foreign interference are causing hold ups and issues for grant applications. www.timeshighereducation.com/news/grant-d... “The requirements we now have to go through…are more extensive and time-consuming than we had imagined,”

Grant delays feared as ARC ramps up ‘due diligence’

Researchers brace for renewed funding uncertainty as security checks prove ‘more time-consuming than imagined’

timeshighereducation.com

A. baumannii is one of the most notorious multidrug-resistant pathogens, capable of forming drug-tolerant biofilms that make infections exceptionally difficult to treat. But how are these complex microbial fortresses built? Just published in Nat Comms. pubmed.ncbi.nlm.nih.gov/41654547/

Antiparallel stacking of Csu pili drives Acinetobacter baumannii 3D biofilm assembly - PubMed

Many Gram-negative nosocomial pathogens rely on adhesive filaments, known as archaic chaperone-usher pili, to establish stress- and drug-resistant, multi-layered biofilms. Here, we uncover the mechanism by which these pili build three-dimensional (3D) biofilm architectures. In situ analyses of Acine …

pubmed.ncbi.nlm.nih.gov

Beautiful work Deb! Check out these structures? Biofilms are very interesting. 🧶🧬

Debnath Ghosal@debnathghosal.bsky.social · 8mo ago

A. baumannii is one of the most notorious multidrug-resistant pathogens, capable of forming drug-tolerant biofilms that make infections exceptionally difficult to treat. But how are these complex microbial fortresses built? Just published in Nat Comms. pubmed.ncbi.nlm.nih.gov/41654547/

Fabien Munder - New strategies to fight AMR. Bacterial competition via L-type pyocins; targeting (1) BamA EC loop 6, (2) beta-strand 1. Inhibit beta barrel assembly by blocking the BAM barrel lumen. Increase cell permeability - holes in the OM. 👏 (EMReady post-processing) 🤓 #lorneproteins2026

Really beautiful cryoET of periplasmic flagella structures and amazing animations

Lorne Proteins@lorneproteins.bsky.social · 8mo ago

S3: Luca Troman-Spirochete flagellar motors rotate in opposite directions; periplasmic flagella are more complex. Treponema denticola. 2 motors, thick and thin flagella. SPA Native flagella isolation w optiprep cushion, inner core, outer sheath, mystery density - modelangelo! 🕵‍♀️ #lorneproteins2026

Kate Michie talking about her work on archaeal cytoskeleton. @lorneproteins.bsky.social

Neg charged lactate binds pocket when His positively charged. Lactate binds favourably, but only lactic acid can leave. Proton enters to charge His, attracts negative lactate, proton neutralises lactate to lactic acid, then LA leaves.

First speaker Ashleigh Kropp of the most fun session of the Lorne Protein Meeting the Anders Young Investigators session. @lorneproteins.bsky.social

Yan Jiang is the next Anders session speaker presenting her work on the SLC1A transporter. @lorneproteins.bsky.social

Emily Furlong (UQ alumnus 😄) talking about her new work on ABC transporters. @emfurlong.bsky.social @lorneproteins.bsky.social

Session 7 ⚡️🌩 talks time!! Jack Zeng Unravelling Promiscuity - OCT1 gating - structures of ligand bound states. Interrogating binding and transport specificity and mechanism. #lorneproteins2026

No, I was wrong. The ARC just posted on X – you know, the platform that whose offices have been raided by French police because it produces and hosts child exploitation materials? Yes, that X.