Were you at #USHUPO2026 and saw Ben @proteomicsnews.bsky.social and Renã Robinson with Natalie Clark @nmclark2.bsky.social for a LIVE recording of #THEProteomicsShow? Well, I wasn't either, but we now we can bathe our ears in this audio. Find it wherever you find podcasts. anchor.fm/theproteomic...
Dr. Natalie Clark
@nmclark2.bsky.social
Computational Scientist in the Proteomics Platform at the Broad Institute. Systems biologist integrating ALL the omics data. Views are my own. She/her.
Back in my day, AI used to stand for Adobe Illustrator! And we hated that, too!
President Donald Trump’s administration has terminated $352 million in grants and contracts this year to the Research Triangle Institute, the United States’s third largest independent research organization, a report estimates.
Cuts in global health and climate hit Research Triangle Institute hard
“Financial drubbing” underscores reliance of some independent research organizations on federal funding
science.org
Please share & RSVP to join the November 25th webinar! Hear from the 2025 Philip N. Benfey Arabidopsis Community Lifetime Achievement Awardees! bit.ly/naascawards @plantevolution.bsky.social
Healey: Massachusetts insurers have to cover the cost of all vaccines approved by the state, no matter what the brainworm in chief says. This includes MassHealth and GIC.
Regulatory network topology and the genetic architecture of gene expression www.biorxiv.org/content/10.1... 🧬🖥️🧪
Proud to share our collaborative effort between the Taiwan Cancer Moonshot Program and the NCI’s Clinical Proteomic Tumor Analysis Consortium (CPTAC), delivering an integrative proteogenomic atlas of lung adenocarcinoma. Open-access link: authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
Movie you've watched more than 6x using a gif (no Disney, Star Wars, LOTR, or Star Trek).
a man wearing a helmet is giving the middle finger in front of a sign that says 440
ALT: a man wearing a helmet is giving the middle finger in front of a sign that says 440
media.tenor.com
Movie you've watched more than 6x using a gif (no Disney, Star Wars, LOTR, or Star Trek).
We're looking for a new PhD candidate to join the lab. Please share 🌱😄
Here's a database from UCLA on Non-NIH funding opportunities ranging from grad students to faculty from a wide range of biological and medical disciplines: biofund.healthsciences.ucla.edu/crt-funding/...
BioFund - a Non-NIH Funding Database | crt-funding
biofund.healthsciences.ucla.edu
HEY PROTEOMICS PEOPLE! Can you comment here where you learned to do proteomics? I started putting up a survey but based on just the 64 people on our podcast there are too many options for a multiple choice survey effectively. Thank you!
Awesome to see my good friend & amazing scientist Jeff Dangl share with Jonathan Jones and Brian Staskawicz the 2025 Wolf Prize in Agriculture for their pioneering work on plant disease resistance 🧪1/n wolffund.org.il/jeffery-l-da...
Can someone please explain to my 11 month old that we lost an hour so he should sleep an hour later, not get up an hour earlier? In other news, this is my annual complaint about DST. I'm so tired 😴
My daughter's daycare just sent out an email about potentially needing to layoff staff because new babies about to start withdrew because of parental job losses. So if you're wondering how government layoffs and mass contract cancellations will affect the economy, here's an example
Travel permits of all US government employees (USDA, NSF) have been revoked shortly before the the maize meeting affecting: - The chair of the meeting - The winner of the most prestigious McClintock award - A plenary speaker - Two short talk presenters - 22 scientists presenting posters. #MGM2025
NIH websites are down because of a DNS attack. They are working on it. Via reddit.
Just arrived for #USHUPO2025! Excited to give a talk at the #CPTAC workshop Monday evening. Feel free to reach out directly if you'd like to chat about multi-omics analysis!
congrats to Brendan Floyd, postdoc in @carolynbertozzi.bskyverified.social lab on his exciting work "mapping the nanoscale organization of the human cell surface proteome" High resolution, High Effort, and Creative Analytics produce new views of the cell surface www.biorxiv.org/content/10.1...
To US colleagues who have lost or are in imminent danger of losing their jobs: please DM whether we can accommodate your research.
Honored to be interviewed about the rising incidence of lung cancer in non-smokers and especially females on @wral.bsky.social to shed light on #LCSM during #LungCancerAwarenessMonth and highlight the #HearHer campaign www.wral.com/lifestyle/he... @younglungcancer.bsky.social
Rising lung cancer cases in nonsmoking women under 50: Experts urge awareness
An unexpected surge in lung cancer cases among nonsmoking women under 50 is raising alarms among oncologists, emphasizing the need for heightened awareness.
wral.com
Our Arabidizzle ubiquitinome paper is published! Awesome collaboration w @diorkelley.bsky.social lab lead by Gaoyuan Song - key contributions from so many others (@dormichicken.bsky.social @nmclark2.bsky.social) @theplantcell.bsky.social #proteomics #PlantScience academic.oup.com/plcell/advan...
Quantitative proteomics reveals extensive lysine ubiquitination and transcription factor stability states in Arabidopsis
An antibody-based approach to enrich ubiquitinated peptides reveals Arabidopsis root, seedling, and leaf ubiquitinomes.
academic.oup.com
"Dark TFs": new manuscript mapped 166 uncharacterized human transcription factors, finding half bind genomic "dark matter," often closed chromatin rich in transposable elements. www.biorxiv.org/content/10.1...
There is a whole crop of us who lost our minds trying to ramp up careers while handling ever-changing childcare arrangements. Our family went ~ two years without a solid month of scheduled childcare. It has taken so much time & energy to recover, w/the loss of productivity still being felt.
The parents of the youngest children are not okay
An epidemiologist on the health risks of the omicron variant, child care issues, and the unique pandemic struggles of working parents.
vox.com
HEY PARENTS IN ACADEMIA!!! What do you wish people knew about your experience and how parenting impacts you/your career/your science/etc???
To read more about Boltz-1 check out: - Our short blog-post jclinic.mit.edu/boltz-1/ - Our technical report: gcorso.github.io/assets/boltz... - Our code, model and instructions: github.com/jwohlwend/bo... I'll share a separate thread with more details about the process and interesting findings!
Introducing Boltz-1: Democratizing Biomolecular Interaction Modeling – MIT Jameel Clinic
jclinic.mit.edu
Great to be posting science again!! Very proud of this work, thanks to a wonderful collaboration with Forest White lab at MIT, Cantley lab at DFCI, and leb by the amazingly talented @alissandra-hillis.bsky.social! Published as fully @openaccess.bsky.social in PNAS. www.pnas.org/doi/10.1073/...
A few years old, but worth a read (perhaps in particular to those who do ML in BIO or take biological databases for granted) 🧪🧬🖥️ "How Margaret Dayhoff Brought Modern Computing to Biology" www.smithsonianmag.com/science-natu...
How Margaret Dayhoff Brought Modern Computing to Biology
The pioneer of bioinformatics modeled Earth’s primordial atmosphere with Carl Sagan and made a vast protein database still used today
smithsonianmag.com
You might be amused that similar to your astronomy single cell application, she likewise found cross over between the fields. Really incredible with an abrupt ending.
Here is a paper where I would just like to say "Thank you" to the authors. I thoroughly enjoyed this. I hope you do too. #GENESky #RNAsky #CANsky #genomics #bioinformatics 🧪 🧬💻 🔎 microproteins www.cell.com/cell-reports...
RNA splicing junction landscape reveals abundant tumor-specific transcripts in human cancer
Li et al. thoroughly analyzed RNA splicing junctions in 34,775 samples and identified 29,051 tumor-specific transcripts that may serve as cancer driver genes, neoantigens, and circulating biomarkers.
cell.com
Watch Joanne's call to arms for plant scientists to fight climate change: www.ted.com/talks/joanne... #plantscience
How supercharged plants could slow climate change
Plants are amazing machines -- for millions of years, they've taken carbon dioxide out of the air and stored it underground, keeping a crucial check on the global climate. Plant geneticist Joanne Chor...
ted.com