Promises to be another great meeting, bringing the fab developmental biology community together!

British Society for Developmental Biology@bsdb.bsky.social · 3mo ago

Save the date! The 2027 BSDB Spring Meeting will take place on 19 - 22 April in Edinburgh. An exciting programme with a fantastic lineup of speakers showcasing developmental biology across scales! More details soon!

As a Guest Editor for @JoVE, @m-stower.bsky.social and I are organising a Topical Collection titled “Understanding Morphogenesis During Embryonic Development”. Interested in contributing? Please submit an abstract here: app.jove.com/methods-coll...

We are happy to share our new bioRxiv pre-print on A-P axis patterning. A great collaboration with Felix Zhou (UT Southwestern) & the Yeomans group (Physics, Oxford) www.biorxiv.org/content/10.6...

@shifaant.bsky.social @srinivas-lab.bsky.social peaking into the chick heart - love it!!

Institute of Developmental & Regenerative Medicine@idrm.ox.ac.uk · 8mo ago

This week's scientific video, created by Dr Shifaan Thowfeequ from the Shankar Srinivas lab, is titled “Chasing the wave – in search of the origins of the first heartbeat.” The video captures the mechanical and chemical dynamics of an embryonic chick heart as it first forms and starts to beat.

The 'sparks' of life! Our latest work on the role of #calcium dynamics in the early #embryo. 🎇🔬🐁 @idrm.ox.ac.uk @oxforddpag.bsky.social @srinivas-lab.bsky.social #lightsheetmicroscopy #GCAMP

PLOS Biology@plosbiology.org · 10mo ago

During #development, distal visceral #endoderm (DVE) cells migrate to shape A-P axis specification. @m-stower.bsky.social @srinivas-lab.bsky.social &co reveal the role of Ca2+ dynamics in this, showing that inhibition of #calcium transients causes DVE arrest @plosbiology.org 🧪 plos.io/4nHWxF4

During #development, distal visceral #endoderm (DVE) cells migrate to shape A-P axis specification. @m-stower.bsky.social @srinivas-lab.bsky.social &co reveal the role of Ca2+ dynamics in this, showing that inhibition of #calcium transients causes DVE arrest @plosbiology.org 🧪 plos.io/4nHWxF4

#OnThisDay in 1858, a seminal journal article comprised of papers by Alfred Russel Wallace FRS and Charles Darwin FRS on the theory of evolution by natural selection was published by the Linnean Society, the first public announcement of the theory of evolution. bit.ly/3k8fq4u

*TODAY Wed 4 June 15:00 BST (UTC+1)* Development presents... webinar, celebrating the winners of the @bsdb.bsky.social postdoc poster prize from the Biologists @ 100 conference. We'll hear from @giuliapaci.bsky.social and @shifaant.bsky.social Register here: us02web.zoom.us/webinar/regi...

Very happy to share I've written a review on placental vascular formation in mice and humans, now published in @dev-journal.bsky.social. journals.biologists.com/dev/article/... @idrm.ox.ac.uk Funded by the @thebhf.bsky.social

Feto-placental blood vessel development

Summary: This Review contains an overview of placental vascular development and pathologies in mice and humans and highlights key remaining questions in the field.

journals.biologists.com

*This Wed 4 June 15:00 BST* Register to attend our next Development presents... webinar, celebrating the winners of the @bsdb.bsky.social‬ postdoc poster prize from the Biologists @ 100 conference. We'll hear from @giuliapaci.bsky.social‬ and @shifaant.bsky.social‬ us02web.zoom.us/webinar/regi...

Register now to attend our #DevPres webinar next week, featuring the winners of the @bsdb.bsky.social poster prize, @shifaant.bsky.social and @giuliapaci.bsky.social, and chaired by Abigail Tucker. 4 June at 15:00 BST us02web.zoom.us/webinar/regi...

Visa costs will limit Britain's ability to court those who may seek to leave the U.S. after Trump's administration cut funding for universities and research bodies, says Professor Alison Noble FRS, Foreign Secretary of the Royal Society: www.reuters.com/world/uk/hig...

High UK visa costs deter international scientists and engineers

It took Ed Roberts over a year to find a senior scientist to work at his cancer research laboratory in Scotland, a delay he blames on high UK visa costs that made it harder to attract international workers.

reuters.com

This is the head of a chicken embryo after 16 days of development, imaged with light sheet microscopy 🐣🔬🧪

The sun is shining over the beautiful city of Liverpool for @biologists.bsky.social ‘s Centenary Meeting ( #biologists100)

Very happy to share our work on lymphatic endothelial cell specification, which was published in Nature Cardiovascular Research this week.

✨Excited to share our work revisiting the developmental origins of mammalian lymphatic endothelial cells.✨ A summary of our key findings using scRNA-seq, snMultiome-seq and imaging to show the direct specification of mesenchymal progenitors to LECs🧵 #blutorial #blabstract tinyurl.com/LECspec

Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research

Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...

tinyurl.com

Excited to have provided the cover images for the new Kaufman's Atlas of Mouse Development Supplement (edited by Gillian Morriss-Kay & Shankar Srinivas) – the go-to reference resource for all mammalian developmental biologists.

Have always been fascinated about these elusive giants–the beaked whales. Until now nothing was known about this extant species; known from only seven records and have never been seen alive at sea. Turns out it has a nine-chambered stomach and vestigial teeth! www.doc.govt.nz/news/media-r...

Spade-toothed whale reveals new discoveries

Vestigial teeth were just one of many new discoveries made by scientists during the dissection of the rarest whale in the world, Te Rūnanga o Ōtākou says.

doc.govt.nz

Happy to share our latest review by @shifaant.bsky.social with @cwhanna.bsky.social. A detailed look at extraembryonic tissues – the 'other half' of the conceptus. www.nature.com/articles/s41... @natrevmcb.bsky.social

Origin, fate and function of extraembryonic tissues during mammalian development - Nature Reviews Molecular Cell Biology

During mammalian embryogenesis, extraembryonic tissues are required for the patterning and morphogenesis of the embryo. This Review discusses how signalling networks and epigenetic modifications regul...

nature.com

Beautifully written essay by @jbwallingford.bsky.social that every developmental biologist should read. aeon.co/essays/after...

After 3,000 years of science, the embryo is very different | Aeon Essays

For 3,000 years, humans have struggled to understand the embryo. Now there is a revolution underway

aeon.co

Nice to see our latest review published in @natrevmcb.bsky.social today – a collaborative exploration of mammalian extraembryonic development with @cwhanna.bsky.social for an invaluable epigenetic focus. @srinivas-lab.bsky.social www.nature.com/articles/s41...

Origin, fate and function of extraembryonic tissues during mammalian development - Nature Reviews Molecular Cell Biology

During mammalian embryogenesis, extraembryonic tissues are required for the patterning and morphogenesis of the embryo. This Review discusses how signalling networks and epigenetic modifications regul...

nature.com

A scenic walk to work this morning. Oxford, Oxfordshire.

Happy to have the Srinivas lab on Bluesky! Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo www.biorxiv.org/content/10.1...

Feeling Festive! Very happy to share our new bioRχiv pre-print – investigating the role of calcium signalling in the early mouse embryo: www.biorxiv.org/content/10.1...

Calcium signalling is required for anterior patterning in the mouse embryo https://www.biorxiv.org/content/10.1101/2024.11.14.623160v1

Calcium signalling is required for anterior patterning in the mouse embryo https://www.biorxiv.org/content/10.1101/2024.11.14.623160v1

Anterior-Posterior axis formation in the mouse embryo requires the active migration of the DVE cell

biorxiv.org