Pravesh Parekh

@parekhpravesh.bsky.social

Postdoctoral researcher | Neuroimaging | Genetics | Machine learning | Psychiatry | Progressively dystopian

Pleased to share that FEMA-Long is now published in PLOS Genetics! FEMA-Long, an efficient mixed-effects modeling method, includes modeling unstructured covariance, spline and spline interactions, and performing longitudinal GWAS to discover time-dependent genetic effects doi.org/10.1371/jour...

FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets

Author summary Most large-scale datasets have complexities such as repeated measures, related individuals, or other dependencies across samples, preventing the use of standard regression approaches fo...

doi.org

Yes, Swiss scientist Fritz Zwicky coined the term “dark matter” which is impressive, but he also coined the term “spherical bastard” to describe people who are bastards no matter which way you look at them, and I think that should be celebrated more.

More context on this #Artemis II image: * This is the night side, lit by moonlight. You can see city lights in Spain & Portugal, & a sliver of day at lower right * The Sun is entirely behind Earth, which makes it a kind of solar eclipse, but w/ Earth doing the eclipsing instead of the Moon: ☀️🌍🚀🌕

A full disc image of Earth, as seen from the Orion Crew Module. The planet is a pale blue, swirling with white clouds and glowing slightly lighter blue in place from reflected light. At lower left, a large brown landmass is Africa, with Spain and Portugal with twinkling lights where the planet curves. At top right, auroras glow in a thin green glow, just barely separated from the planet's surface. Earth is set against the black of space (pic: NASA/R.Wiseman)

Really sick of AI being forced down everyone’s throat. AI can be a useful tool for some activities (mostly improving efficiency on monotonous tasks). But the sales pitch is insane & the idea that if you’re not integrating AI you are going the way of the 🦕 is insulting.

A thread of how to say “nobody asked you” from around the world, starting with this one… A Lithuanian way of telling someone to mind their own business is ne tavo kiaulės, ne tavo pupos. It means “not your pigs, not your beans.”

Motion Insensitive Resting-State Analysis (MIRA): a new way to perform motion correction that effectively removes the confounding effect of motion on the rsfMRI derived correlation matrices! Meet me at poster F13 and at the flash talk session today at #Flux2025 to find out more about this!

Motion Insensitive Resting-State Analysis (MIRA): meet me at poster 1595 at #OHBM2025 to discuss a new way of performing motion correction for resting state fMRI that effectively removes the confounding effect of motion on rsfMRI derived correlation matrices!

Stoked to be attending #OHBM2025 this week with our UCSD / JCVI team! If you’re here, be sure to stop by my poster to see some cool work from our lab using GAMMs: 📅 W/Th June 25th/26th 🧠 "Nonlinear age trajectories of subcortical microstructural and morphometric changes in the ABCD study"

Brisbane cityscape with the Brisbane sign in the foreground

Coming June 2025! We are excited to launch the NIH Brain Development Cohorts (NBDC) Data Hub. This new data ecosystem will host & facilitate access to data from the Adolescent Brain Cognitive Development (ABCD) Study & the HEALthy Brain and Child Development (HBCD) Study. 1/13

#lirpaloof Since it's already 2025-04-01 for most of the world ... a slightly updated version of the `celebrate` package: `remotes::install_github("bbolker/bbmisc/celebrate")`. (Description: Celebrate your successes and mourn your failures.) Now supports `htest` objects!

celebrate              package:celebrate               R Documentation

Audio 'announcements' when printing model summaries

Description:

     The only function of this package is to augment the printing of
     model summaries with appropriate sound effects based on whether
     you have achieved the magical p<0.05 level of significance for at
     least one variable (not including the intercept - we have to try
     to be a _little_ bit sensible ...)

Details:

     Sounds are taken from <http://freesounds.org>

     To set an alpha-level different from 0.05, you can specify
     ‘options(celebrate.alpha = <value>)’

        • fanfare: user primordiality,
          <https://www.freesound.org/people/primordiality/sounds/78823/>
          (CC BY 3.0)

        • trombone: user kirbydx,
          <https://www.freesound.org/people/kirbydx/sounds/175409/>
          (CC0)

Examples:

     ## Not run:
     
     m1 <- lm(speed~dist,cars)
     m2 <- lm(Income~Population,data.frame(state.x77))
     summary(m1)
     summary(m2)
     ## chi-squared test
     M <- as.table(rbind(c(762, 327, 468), c(484, 239, 477)))
     dimnames(M) <- list(gender = c("F", "M"),
                         party = c("Democrat","Independent", "Republican"))
     (Xsq <- chisq.test(M))  # Prints test summary
     boring <- matrix(c(6,5,4,5), nrow = 2)
     (chisq.test(boring))
     ## End(Not run)

A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.” Absurd we still need to go through this 🧪👩‍🔬

There have been people less than helpful in my journey here. I wanted to acknowledge those too, bc I know I am not unique in this experience.
No thank you to the physics study assoc that made me sing songs about how women couldn't study physics without sleeping with the professor, the day I stepped into university life. No thank you to the 5th year physics student that decided to assign me a stripper name within the first minute of meeting me in the physics coffee corner in my first year. No thank you to the technician that was responsible for onboarding me on the use of the cluster in my third year who raised his eyebrows and asked me if that meant I was some sort of computer girl. No thank you to the senior researcher that sent me utterly inappropriate texts after a conference, then proceeded to apologise months later by telling me they had not been meant for me anyway so no hard feelings remain hopefully And no thank you to him for attending every conference I've been to since. No thank you to the people who told me that it was surprising that I was doing a PhD since I was a girl. No thank you to the man who mistook me for a coffee lady at a conference, and after having to correct him two times that I did not work there, responded with you should consider it. No thank you to the researcher that asked me what I was wearing underneath my outfit during a conference. No thank you to the physicist who declared to a room full of other physicists that biologists don't know how to design an experiment. No thank you to the people who have called me scary instead of strong and intimidating instead of intelligent.
And finally, no thank you to the exec board of the TU Delft, whose knee-jerk reaction to being held up a mirror about the social safety at the university, was to sue the party holding up the mirror instead of looking at the problems they highlighted.
... You have made me feel like I do not belong in science & I cannot forgive you for that.

 “people won’t take us seriously if we speak plainly about what we’re doing, so we have to smoke and mirror some fake math at them to get them to show us respect”.

When I was a young man there were whispered rumors among the elders that they could remember their own elders talking about a time when getting grants had been a means for doing science, rather than vice versa.

Are you an early career researcher at @uio.no? Next Wednesday at 1pm I’ll be running a career development workshop for UiO ECRs, in which I’ll cover how a “start-up of one” mindset can be used for navigating academic careers. For more details ⬇️

The Start-Up Scholar - The Faculty of Mathematics and Natural Sciences

Join us for an interactive workshop that has been designed to help PhD candidates, Postdoctoral Fellows and Early Career Researchers plan their careers using a start-up framework.

mn.uio.no