“Motion insensitive resting state analysis” (MIRA) - meet me at #OHBM2026 at poster 2400 today and tomorrow to talk about a new way of performing motion correction for resting state fMRI!
Pravesh Parekh
@parekhpravesh.bsky.social
Postdoctoral researcher | Neuroimaging | Genetics | Machine learning | Psychiatry | Progressively dystopian
Pleased to share that FEMA-Long is now published in PLOS Genetics! FEMA-Long, an efficient mixed-effects modeling method, includes modeling unstructured covariance, spline and spline interactions, and performing longitudinal GWAS to discover time-dependent genetic effects doi.org/10.1371/jour...
FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets
Author summary Most large-scale datasets have complexities such as repeated measures, related individuals, or other dependencies across samples, preventing the use of standard regression approaches fo...
doi.org
I will be presenting tricks and tips for "Efficient large-scale statistical analyses in the big data era" today at the educational session "The Research Lifecycle: A Primer on Open and Sustainable Science Practices" at #OHBM2026. Happy to discuss! Course material here: github.com/parekhpraves...
GitHub - parekhpravesh/efficientAnalyses: Code and tutorials demonstrating how to perform large-scale statistical analyses in a computationally efficient manner
Code and tutorials demonstrating how to perform large-scale statistical analyses in a computationally efficient manner - parekhpravesh/efficientAnalyses
github.com
Job ad (1/2): Postdoc fellowship in the AFNI group (SSCC, NIMH, NIH, USA). FMRI/MRI methods dev, software design, statistics, analysis, data viz, quality control, machine learning and more! Please see: discuss.afni.nimh.nih.gov/t/job-ad-pos... I am happy to chat at OHBM+Brainhack. Please share!
Yes, Swiss scientist Fritz Zwicky coined the term “dark matter” which is impressive, but he also coined the term “spherical bastard” to describe people who are bastards no matter which way you look at them, and I think that should be celebrated more.
More context on this #Artemis II image: * This is the night side, lit by moonlight. You can see city lights in Spain & Portugal, & a sliver of day at lower right * The Sun is entirely behind Earth, which makes it a kind of solar eclipse, but w/ Earth doing the eclipsing instead of the Moon: ☀️🌍🚀🌕
Really sick of AI being forced down everyone’s throat. AI can be a useful tool for some activities (mostly improving efficiency on monotonous tasks). But the sales pitch is insane & the idea that if you’re not integrating AI you are going the way of the 🦕 is insulting.
For people using the @ukbiobank.bsky.social UKB RAP cloud system for brain imaging analyses: In order to make RAP much easier to use, we have created a Docker which is easy to install and gives you a graphical desktop, FSLeyes and the HCP wb_view. docs.google.com/document/d/1...
Imaging-friendly docker for UK Biobank RAP
An Easy Docker for Brain Imaging Visualisation on UKB RAP Paul McCarthy1 Stephen Smith1 1FMRIB, OxCIN, NDCN, Oxford University, UK Queries: email paul.mccarthy@ndcn.ox.ac.uk and stephen.smith@ndcn....
docs.google.com
A thread of how to say “nobody asked you” from around the world, starting with this one… A Lithuanian way of telling someone to mind their own business is ne tavo kiaulės, ne tavo pupos. It means “not your pigs, not your beans.”
Motion Insensitive Resting-State Analysis (MIRA): a new way to perform motion correction that effectively removes the confounding effect of motion on the rsfMRI derived correlation matrices! Meet me at poster F13 and at the flash talk session today at #Flux2025 to find out more about this!
New paper out 🚨 in BMC Medical Research Methodology We assessed the prevalence of transparency-related practices in epidemiological secondary analyses for the Norwegian mother, father, and child cohort (MoBa). shorturl.at/604hn
Transparency in epidemiological analyses of cohort data a case study of the Norwegian mother, father, and child cohort study (MoBa) - BMC Medical Research Methodology
Background Epidemiological research is central to our understanding of health and disease. Secondary analysis of cohort data is an important tool in epidemiological research but is vulnerable to pract...
bmcmedresmethodol.biomedcentral.com
The ABCD Study 6.0 release is finally here! 🧠 Apply for data access here @theabcdstudy.bsky.social www.nbdc-datahub.org
NBDC Data Hub
NIH Brain Development Cohorts (NBDC) Data Sharing Platform: Unifying ABCD and HBCD data management in one powerful platform.
nbdc-datahub.org
Motion Insensitive Resting-State Analysis (MIRA): meet me at poster 1595 at #OHBM2025 to discuss a new way of performing motion correction for resting state fMRI that effectively removes the confounding effect of motion on rsfMRI derived correlation matrices!
Stoked to be attending #OHBM2025 this week with our UCSD / JCVI team! If you’re here, be sure to stop by my poster to see some cool work from our lab using GAMMs: 📅 W/Th June 25th/26th 🧠 "Nonlinear age trajectories of subcortical microstructural and morphometric changes in the ABCD study"
Meet me at #OHBM2025 poster 689 today/tomorrow to discuss using Fast and Efficient Mixed-Effects Algorithm (FEMA) for mixed-effects modeling with unstructured covariance and splines, perform longitudinal GWAS, and discover time-dependent genetic effects! www.biorxiv.org/content/10.1...
biorxiv.org
Led by the incredible @gauravbhalerao.bsky.social
New paper in Imaging Neuroscience by Gaurav Bhalerao, Ludovica Griffanti, et al: Automated quality control of T1-weighted brain MRI scans for clinical research datasets: methods comparison and design of a quality prediction classifier doi.org/10.1162/IMAG...
Coming June 2025! We are excited to launch the NIH Brain Development Cohorts (NBDC) Data Hub. This new data ecosystem will host & facilitate access to data from the Adolescent Brain Cognitive Development (ABCD) Study & the HEALthy Brain and Child Development (HBCD) Study. 1/13
Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects! www.biorxiv.org/content/10.1...
FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets
Linear mixed-effects (LME) models are commonly used for analyzing longitudinal data. However, most applications of LME models rely on random intercepts or simple, e.g., stationary, covariance. Here, w...
biorxiv.org
FYI, if you want to be prepared to apply for the next ABCD Study data release, prepare for these new NIST security requirements 🧠: @ohbmofficial.bsky.social abcdstudy.org/scientists/d...
Data Sharing - ABCD Study
abcdstudy.org
#lirpaloof Since it's already 2025-04-01 for most of the world ... a slightly updated version of the `celebrate` package: `remotes::install_github("bbolker/bbmisc/celebrate")`. (Description: Celebrate your successes and mourn your failures.) Now supports `htest` objects!
Did you know that all the fine artisanal memes from my stats lectures are available in the course repo? Reuse and remixing freely encouraged github.com/rmcelreath/s...
Dive into stat modeling&applications, relaxing assumptions, predictive accuracy, preserving information, imputation, model validation, Bayesian models, causal specification+many controversial topics: Regression Modeling Strategies course May 15-16, 19-20 hbiostat.org/doc/rms/4day.html #StatsSky
RMS
hbiostat.org
A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.” Absurd we still need to go through this 🧪👩🔬
Happy 30th birthday year to SPM!! 🎈🍰 To get the party started, we are delighted to announce SPM 25.01, a major new version of the open-source neuroimaging software. Read the preprint to discover what's new arxiv.org/pdf/2501.12081 and download SPM for free from Github github.com/spm/spm/rele...
arxiv.org
REFUSE. (lexical stress)
7 steps to junk science that can achieve worldly success statmodeling.stat.columbia.edu/2025/01/17/7...
7 steps to junk science that can achieve worldly success | Statistical Modeling, Causal Inference, and Social Science
statmodeling.stat.columbia.edu
“people won’t take us seriously if we speak plainly about what we’re doing, so we have to smoke and mirror some fake math at them to get them to show us respect”.
When I was a young man there were whispered rumors among the elders that they could remember their own elders talking about a time when getting grants had been a means for doing science, rather than vice versa.
Are you an early career researcher at @uio.no? Next Wednesday at 1pm I’ll be running a career development workshop for UiO ECRs, in which I’ll cover how a “start-up of one” mindset can be used for navigating academic careers. For more details ⬇️
The Start-Up Scholar - The Faculty of Mathematics and Natural Sciences
Join us for an interactive workshop that has been designed to help PhD candidates, Postdoctoral Fellows and Early Career Researchers plan their careers using a start-up framework.
mn.uio.no