We're recruiting a postdoc to study the molecular and cellular basis of the male bias in medulloblastoma! Please apply through the DKFZ Postdoc Program until September 8th. Our project is under B430_Developmental Origins. Please get in touch with questions! jobs.dkfz.de/en/jobs/1687...

DKFZ Postdoctoral Fellowships 2026

jobs.dkfz.de

Do you use eLabFTW? Starting from a blank team can be daunting, so we've shared our reusable template collection. We hope to grow it into a community resource - feedback, ideas & contributions are very welcome! github.com/sfb1638/elabftw-templates #eLabFTW #RDM

New positions in the lab! Our project on chemoresistance and genome instability has been funded by German Cancer Aid - Krebshilfe_Bonn We are hiring: 🔬 PhD student 🔬 Postdoc Focus: DNA repair, mutagenesis & functional genomics. Get in touch! #PhD #Postdoc #CancerResearch

We are looking for a postdoc to join us on the quest for understanding RNA Pol II destruction machines! If you are curious why more than 80% of Pol II are removed from genes, check out the post below: www.nature.com/naturecareer...

Postdoctoral Scientist | PNAC | Dr Ana Tufegdzic Vidakovic | LMB 2142 - Cambridge, Cambridgeshire (GB) job with MRC Laboratory of Molecular Biology (LMB) | 12857096

Postdoctoral Scientist Salary £42,694 per annum pro rata Fixed term for 3 years MRC Laboratory of Molecular Biology, Cambridge, UK Applications are...

nature.com

🧬🧬🧬 REGISTRATION JUST OPENED! Make sure you join our DNA REPAIR MEETING 2026 ON PHYSIOLOGICAL CAUSES AND CONSEQUENCES OF GENOME INSTABILITY in Cologne, September 7-9, organized by the German Society for DNA Repair (DGDR) and the @dfg.de Research Unit 5504. www.for-5504.com/en/197/Confe...

Great to see this team effort out, in which we find a new player in genome stability and a neurodevelopmental disease caused by its loss. Fantastic collaboration with @drjhujh.bsky.social and @profstewartlab.bsky.social alongside @sorenhough.bsky.social and friends in @spjacksongroup.bsky.social.

EMBO Molecular Medicine@embomolmed.org · 8mo ago

Loss of CTLH component MAEA impairs #DNArepair and replication and leads to #DevelopmentalDelay By S. Hough, S. Jackson & colleagues @cam.ac.uk @cruk-ci.bsky.social 🗞️ doi.org/10.1038/s443...

Brian Huntly and I are looking to recruit a postdoc to investigate a promising novel therapeutic target in B-ALL @scicambridge.bsky.social. This new CRUK-funded project will involve collaboration with Prof Sir Steve Jackson's group @cruk-ci.bsky.social and the CRUK Functional Genomics centre.

Really cool work from our KiTZ colleagues!

Grünewald Lab@grunewaldlab.bsky.social · last yr.

Very proud on our stellar Alina Ritter for her frist first-author paper: Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances #chemotherapy efficacy in #Ewing #sarcoma tinyurl.com/3kcs3bc9 @dkfz.bsky.social @uniheidelberg.bsky.social @nct-heidelberg.bsky.social

Now peer reviewed and in its final form @natcomms.nature.com www.nature.com/articles/s41...

Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability - Nature Communications

The DNA-dependent protease SPRTN cleaves toxic DNA-protein crosslinks (DPCs). Here, the authors show that SPRTN is activated by DPC-ubiquitylation through an allosteric ubiquitin binding interface. Th...

nature.com

Julian Stingele@jstingele.bsky.social · 2y ago

Happy to share our latest work🍾 🥳 PhD student Sophie Dürauer discovered together with many wonderful collaborators that the ubiquitylation of DNA-protein crosslinks promotes their cleavage by SPRTN more than 100-fold 🧬🔧

We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms. Please get in touch with your CV if you are interested; closing date: 27th June 2025. More details here: candidate.hr-manager.net/ApplicationI...

Postdoctoral Research Associate in the Blackford Group

A position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th

candidate.hr-manager.net

🚨 Check out our latest review in #MolecularCell! We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis. 👏 Outstanding work by our talented PhD Std #MartaValverde @carrerasijc.bsky.social 👉📰 authors.elsevier.com/a/1lDFm3vVUP...

Delighted to share that the results of my main postdoc project are now published in @nature.com 🔗 doi.org/10.1038/s415...

Multigenerational cell tracking of DNA replication and heritable DNA damage - Nature

A multigenerational single-cell tracking approach provides a framework to dissect phenotypic plasticity at the single-cell level, offering insights into cellular processes that may resemble early even...

doi.org

A PhD position is open in my group here in Heidelberg. We'll use cool primary cell models of osteosarcoma and genetic screens to understand and overcome mechanisms of clinically acquired drug resistance. It'll be a blast! karriere.klinikum.uni-heidelberg.de/index.php?ac...

Exciting opportunity for a suitably qualified individual to join us, www.jobs.cam.ac.uk/job/50998/

🚀 New Paper Alert! Our latest @natrevmcb.bsky.social explores how nuclear and genome organization drive DNA double-strand break repair! 🧬 📖 Free access: rdcu.be/edViW Please 🔄 ❤️

Nuclear and genome dynamics underlying DNA double-strand break repair

Nature Reviews Molecular Cell Biology - Changes in nuclear and genome organization promote the repair of DNA double-strand breaks and genome stability. Processes that are involved include the...

rdcu.be

Happy to share our review on the cellular responses to RNA damage 🥂 Congrats to joined first authors Jacqueline Cordes & @shubozhao.bsky.social www.cell.com/cell/fulltex...

Cellular responses to RNA damage

RNA plays a central role in protein biosynthesis and performs diverse regulatory and catalytic functions, making it essential for all processes of life. Like DNA, RNA is constantly subjected to damage...

cell.com

Dear all, Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: k.w.caldecott@sussex.ac.uk

Dear all, my first post! I have postdoc positions available if you would like to join my lab in beautiful Sussex by the Sea! Please contact me on k.w.caldecott@sussex.ac.uk

Happy to share a review written with the wonderful @jstingele.bsky.social on transcription-coupled DPC repair, featuring an overview of new methods, close comparison with TC-NER, comments on clinical implications and plenty of discussion of the unknowns. www.cell.com/trends/cell-...

Transcription-coupled repair of DNA–protein crosslinks

DNA–protein crosslinks (DPCs) are highly toxic DNA lesions that are relevant to multiple human diseases. They are caused by various endogenous and environmental agents, and from the actions of enzymes...

cell.com

Happy to share our latest work🍾 🥳 PhD student Sophie Dürauer discovered together with many wonderful collaborators that the ubiquitylation of DNA-protein crosslinks promotes their cleavage by SPRTN more than 100-fold 🧬🔧

bioRxiv Biochemistry@biorxiv-biochem.bsky.social · 2y ago

Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability https://www.biorxiv.org/content/10.1101/2024.11.26.625192v1

Your chance to join one of the best labs in the field! Great supervisor, great project Sadly, I'm too old

adam grieve@adamgrieve.bsky.social · 2y ago

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

First post here! ✨🦋 There is still time to apply! We have a postdoc position open in our lab at Aarhus University 🇩🇰 We study DNA repair 🧬, combining biochemistry, structural biology, and single-molecule imaging 🔬 Learn more about our research, lab, and Aarhus: sites.google.com/view/alconla...

MCR Lab

We use biochemistry, structural biology and single-molecule imaging to understand how DNA damage is recognised, signalled and repaired. Starting from September 2024, we are based in the Department...

sites.google.com