That's a wrap on #EISG2026 in Barcelona! Three incredible days of islet science, from genomics to clinical translation. Grateful for the talks, discussions, and community that make this meeting so special. Thanks to @lorenzpasquali.bsky.social and @txellrovira.bsky.social for putting this together!
Lorenzo Pasquali
@lorenzpasquali.bsky.social
Research professor @UPFBarcelona genetics and regulatory genomics, islet and chromatin but also father, travelling, campervan, sailing, handbike and kayaking.
Last chance to join us in Barcelona! Registration is closing fast for the #EISG2026 meeting (June 17–19). From pioneering islet biology to the latest in diabetes research, our stellar scientific program is packed. Secure your spot now! 🧬👇 tacticsmd.net/congreso/isl...
Programme - Islet Study Group Conference 2026
The Islet Study Group (ISG) Conference is a leading international forum dedicated to advancing islet biology and diabetes research.
tacticsmd.net
Què fa única cada cèl·lula del pàncrees? 🤔 🧬 SPICEY ho revela identificant gens i regions reguladores de l’ADN. Una eina nova clau per entendre millor el pàncrees en salut i diabetis Llegeix aquí: https://tuit.cat/XVwdK #DiabetesResearch #Bioinformatics @melisupf.bsky.social
Una nova eina ajuda a identificar què fa única cada tipus de cèl·lula del pàncrees - El·lipse
SPICEY, desenvolupada a MELIS-UPF, ajuda a identificar quins gens i regions reguladores són específics de cada tipus de cèl·lula als illots pancreàtics.
tuit.cat
#JobOffer MELIS is looking for a Junior Group Leader Position in Cell Metabolism ✅ PhD in Biology or similar; capacity to lead high-impact research projects; supervision of doctoral theses; teaching ⏰ Deadline: May 2 📍 Barcelona #PRBB Apply: apply.interfolio.com/180316 Details: bit.ly/40N09LX
Registrations and abstract submission for the 2026 𝗘𝘂𝗿𝗼𝗽𝗲𝗮𝗻 𝗜𝘀𝗹𝗲𝘁 𝗦𝘁𝘂𝗱𝘆 𝗚𝗿𝗼𝘂𝗽 #EISG2026 are NOW OPEN Looking forward to seeing you in 𝗕𝗮𝗿𝗰𝗲𝗹𝗼𝗻𝗮! tacticsmd.net/congreso/isl...
Islet Study Group Conference 2026
The Islet Study Group (ISG) Conference is a leading international forum dedicated to advancing islet biology and diabetes research.
tacticsmd.net
0/10 🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology Continuum architecture dynamics of vesicle tethering in exocytosis www.cell.com/cell/fulltex...
Continuum architecture dynamics of vesicle tethering in exocytosis
Data from complementary imaging techniques were integrated into a model that resolves the dynamic exocyst ensemble and membrane architecture during exocytosis, an essential cellular pathway. Sec18 med...
cell.com
Many exciting opportunities for a PhD in Life Sciences in CRG, Barcelona. If you are interested in Genomics of Diabetes check out the offer for a fully funded fellowship in our lab - we will consider candidates with experimental or computational backgrounds. Please spread the word!
Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you. More info: www.crg.eu/en/content/t...
We recently reported that promoter competition can contribute to the robust insulation of gene regulatory domains (www.nature.com/articles/s41...). We now offer a 4-years PhD contract to investigate whether the dirsuption of this regulatory mechanism can lead to congenital defects. More details 👇
#HelmholtzMunich Receives Funding from la Caixa Foundation to Develop Regenerative #Diabetes Therapy t1p.de/ew4iy Focus: Developing stress-resistant beta cells Goal: Overcome immune rejection & enhance #CellReplacementTherapy @heikolickert.bsky.social @lorenzpasquali.bsky.social
Still time to apply! Applications from US welcome – four years can feel longer or shorter depending on where you are 😉
📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. Computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @crg.eu shorturl.at/O3wMi shorturl.at/ieyZy
📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. Computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @crg.eu shorturl.at/O3wMi shorturl.at/ieyZy
Postdoctoral scientist, gene regulatory mechanisms and diabetes | CRG Online Recruitment Portal
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
shorturl.at
🚨🚨🚨 If you're a bioinformatician who loves: 🧬 #SingleCell #LongReadSequencing & #AlternativeSplicing 🚀 Collaborating and travelling Apply to work with us at the spectacular BIMSB (@mdc-berlin.bsky.social) in Berlin + @upf.edu-@crg.eu in Barcelona. Qs: www.transdevolab.com Please RT! 🙏
Exciting study by Amanda Andersson Rolf et al: In vitro expansion of a human fetal #pancreas #stemcell that generates all three pancreatic cell lineages”. www.cell.com/cell/fulltex... New #organoid protocol allows the seemingly indefinite expansion of human fetal pancreatic Lgr5+ stem cell 1/
Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages
Identification of an LGR5 as a marker for a tripotent stem/progenitor cell of the human fetal pancreas. Organoids derived from single LGR5+ cells are capable of long-term expansion in vitro and genera...
cell.com
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
doi.org
1/ 🧬 Single-cell genomics reveals biological variations beyond cell types. Unveiling these in separate latent dim’s is known as disentanglement. Led by @AmirAliMoinfar, we develop DRVI to learn nonlinear, disentangled & interpretable latent spaces. biorxiv.org/content/10.1101/2024.11.06.622266v1