📣 In this Lancet Microbe Perspective, we propose that diabetes-associated metabolic changes may favor Mycobacterium tuberculosis drug tolerance and drug resistance 👊 💊 . Thank you Reinout van Crevel, Julia Brake and all the authors for making it happen! 🙌 🔗 authors.elsevier.com/sd/article/S...

Metabolism as a missing link between diabetes, tuberculosis, and drug resistance?

Diabetes affects approximately one in ten adults globally, and its prevalence is expected to rise substantially over the coming decades. Diabetes doub…

authors.elsevier.com

Excited to announce our new journal from @isme-microbes.bsky.social ISME Host Microbe is live and now accepting submissions. Look forward to receiving your papers! #Microsky 🧫 🦠

Great work from @maxgg.bsky.social and @lockwop.bsky.social! Setting the ground for future research on NTM and acid stress 👏👏👏

Max Gutierrez@maxgg.bsky.social · 7mo ago

Very happy to see this out! Great work by @lockwop.bsky.social @crick.ac.uk and first paper on NTMs from the lab! Parise made a set of 12 fluorescently labelled NTMs covering environmental and opportunistic mycobacteria... onlinelibrary.wiley.com/doi/10.1111/...

A single course of antibiotics can have lasting effects on your gut microbiome, with changes that last well beyond 4 years. Three types of antibiotics stood out for their long term disruptive impact (3 at left, Figure) nature.com/articles/s41...

I’m pleased 🤗 to share our new preprint exploring the mode of action and resistance of the antitubercular drug pyrazinamide (PZA) 💊 Thanks to everyone who have participated 🙌 We hope these findings will help the fight against drug resistance in tuberculosis. www.biorxiv.org/content/10.6...

A big thank you to @cornelluniversity.bsky.social (Ithaca) for the opportunity to share my work and kick off the AMR seminar series💊🦠. Many thanks to David Russell, Brian VanderVen, @nisbettmarie.bsky.social , Anthony Hay and Craig Altier for the brainstormings and warm welcome!

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

Great work by @pierresantucci.bsky.social and co. Always fun and easy to collaborate with you. Thank you for including me in this study 😊

SFM Microbial Pathogenesis@sfmpathogenesis.bsky.social · last yr.

New study shows pyrazinamide kills TB by acidifying bacterial cytosol — not via PanD/CoA depletion. A long-standing debate settled, paving the way for smarter PZA-like drugs. #MicroSky ✍️ J. Laudouze, Y. Antonenko, @alexandregouzy.bsky.social, @pierresantucci.bsky.social & coll. 📖 shorturl.at/tuz6Q

Huge thanks to @marcopsilva.bsky.social, Thales Costa and all the students for the kind invite to speak at the @i3suporto.bsky.social Student symposium! 🌟 Top-notch organization, amazing vibes, and a truly warm welcome, an unforgettable experience! 🙏 #i3Ssymposium

Terrific @embl.org #EMBO meeting on #Tuberculosis in Hyderabad, India! Fantastic to reconnect with friends & colleagues, dive into top-notch science (gut feeling included 😉), and be inspired by brilliant students & postdocs. Great talks, great food, what a blast! 🔥👏 #TBScience #MicroSky

What a great conference #EMBOtuberculosis has been! Amazing science, amazing food and a very friendly community! And it was a pleasure to share the work we’re developing at i3S U. Porto.

Huge congratulations to Robert Wilkinson on being recognised with an OBE in the New Year’s Honours list for his services to infectious disease research. Read more about Robert’s work on tuberculosis at the Crick, @imperialcollegeldn.bsky.social and UCT www.crick.ac.uk/news/2024-12...

Robert J Wilkinson awarded an OBE in the New Year Honours List

crick.ac.uk

I have done this frequently and agree it is very valuable. Removing the presumed quality imprint of the journal name opens up the discussion dramatically in my experience.

eLife@elife.bsky.social · 2y ago

10/ Why should you bring #preprints into your journal club? Here’s what #ECRs stand to gain by looking beyond published papers. https://buff.ly/3VbvNjT

Happy to share my first ever (co)last author paper 🥳 reporting on how Mtb adapts its carbon diet under acid stress. A big thank you to my partners in crime @saehrt.bsky.social and @healycl.bsky.social without who this would not have been possible 😘 journals.asm.org/doi/10.1128/...

An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH | mBio

Despite the availability of antibiotic treatment, M. tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a major infectious disease killer worldwide. A better understanding of the en...

journals.asm.org

Oh look! @asm.org is here now 🧪🧫

My partner has finally joined Blue! Follow him if you love painting, pastels, photography, and beautiful things! 😉

Yannick Verkindere@yanverk.bsky.social · 2y ago

Portrait of an imaginary man. #PastelPainting #FrenchArtist #PastelArt #Art #Portrait #Painting #SoftPastel #PortraitPainting #blueskyart

New Salmonella Persister cells Review is just out❗️ Rachel Giorgio & Sophie Helaine overview the physiology & clinical implications of antibiotic-recalcitrant Salmonella during infection - highlighting important knowledge gaps that need to be addressed… www.nature.com/articles/s41...

Antibiotic-recalcitrant Salmonella during infection - Nature Reviews Microbiology

In this Review, Giorgio and Helaine provide an overview of the physiology of antibiotic-recalcitrant Salmonella enterica during infection, discuss recent insights into the clinical implications of ant...

nature.com

Interested in tissue immunity in infection, focusing on adipose tissue, brain and immunometabolism? Then come join me & @juanquintana.bsky.social at @lydiabeckeriii.bsky.social as a research assistant Email to arrange an informal chat 🧪 #ImmunoSky #LGBTQSTEM www.jobs.manchester.ac.uk/Job/JobDetai...

Research Assistant in Tissue Immunology:Oxford Road

jobs.manchester.ac.uk

I spoke to @mscribe.bsky.social @theguardian.com about the H5N1 case in BC. More and more human cases are occurring, along with mutations that indicate further human adaptation. We need to treat these cases like a warning, because that is what they are. www.theguardian.com/world/2024/n...

Bird flu in Canada may have mutated to become more transmissible to humans

Scientists are racing to understand what a hospitalized teen’s case of bird flu may mean for future outbreaks

theguardian.com

🎉🌍🚀 Our AMAZING PhD superstar, Wendy Le Mouëllic, has landed in Abidjan, Ivory Coast, to take the #MT180 international final by storm! 🏆💥 We’re 1000% sure she’s bringing her A-game (and maybe a trophy 🏅). LET’S GO, WENDY!! 🎤💃 Show the world what IPBS talent is made of! 💪🔥 #TeamWendy #ScienceChampion

Small RNAs are key players in how bacteria adapt to changing environments. Tools like RIL-seq uncover complex sRNA-RNA networks, paving the way for innovative approaches to fight bacterial infections. Check our review in Springer Nature Protocols: link.springer.com/protocol/10....

our #TBSky starter pack is up to 75 people! 💃🏻 i’ve also added in the two largest TB feeds from @gpollara.bsky.social and @tbfighters.org (thank you both!)—you can also get good #TB content in the “posts” section of the starter pack next goal: a #TBSky recurring journal club 🤭 go.bsky.app/Au7nuHk