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Josh Woolley MD/PhD

@trpr-ucsf.bsky.social

Associate Prof and psychiatrist. Studying psychopharmacology including psychedelics and oxytocin. Director of Translational Psychedelic Research (TrPR) Program @UCSF

76 Posts1407 Follower677 Folgt
christine liu / two photon art@christineliu.art · 4w ago

I joined the Sohal lab with one major hypothesis: psychedelic drugs can be powerful psychiatric treatments, depending on underlying neurobiology. Indeed, psilocybin restored cognitive flexibility in one circuit model of dysfunction, but not another! Then, we had to find out how! 🧠🍄🧪

Vikaas Sohal@vikaassohal.bsky.social · 4w ago

New preprint led by @christineliu.art! How do psychedelics improve cognitive flexibility? Psilocybin prevents inflexibility caused by aberrant mesocortical error signaling (but not inflexibility due to other mechanisms); this is tied to plasticity of PFC-MD neurons: www.biorxiv.org/content/10.6...

UCSF Department of Psychiatry and Behavioral Sciences@ucsfpsych.bsky.social · 3mo ago

Read about four ways UC San Francisco researchers are pioneering novel treatments in depression, Parkinson’s, and addiction. https://www.ucsf.edu/news/2026/03/431626/magic-mushrooms-lsd-peek-inside-medicines-psychedelic-promise

From Magic Mushrooms to LSD: A Peek Inside Medicine’s Psychedelic Promise

UCSF research shows psychedelics like psilocybin may treat depression, Parkinson’s, and addiction, offering new hope in clinical trials.

ucsf.edu

Josh Woolley MD/PhD@trpr-ucsf.bsky.social · 9mo ago

The UCSF/VA Translational Psychedelic Research Program seeks postdoctoral fellows to advance rigorous psychedelic-therapy trials investigating neural, cognitive, & behavioral mechanisms in depression, neurodegenerative & eating disorders, chronic pain, and Veterans. 2 years guaranteed, 3rd possible.

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Josh Woolley MD/PhD@trpr-ucsf.bsky.social · last yr.

TrPR recently came together for a half-day retreat. We began with a living timeline: everyone arranged themselves by order of joining, from newest to oldest. I jogged along the line, camera in hand, past the smiling faces on the sunlit terrace of the Pritzker Building—and ended where it all began

Max Wolff@trpwolff.bsky.social · last yr.

Last year, @jacobsaday.bsky.social and @trpr-ucsf.bsky.social asked: "Psychedelic assisted psychotherapy: where is the psychotherapy research?" link.springer.com/article/10.1... How soon can we say "here it comes"?

Psychedelic-assisted psychotherapy: where is the psychotherapy research? - Psychopharmacology

Rationale Psychedelic-assisted psychotherapy (PAP) has emerged as a potential treatment for a variety of mental health conditions, including substance use disorders and depression. Current models of P...

link.springer.com

Max Wolff@trpwolff.bsky.social · last yr.

Finally, leading psychotherapy researchers begin to engage with psychedelic therapy. This is so desperately needed. Let's hope for more to come!

Eric C. Greene@dnacurtain.bsky.social · last yr.

I am a professor at Columbia University. All of the student NIH training grants have been canceled and now there are reports that ALL funding will be frozen. Why are Universities not banding together and speaking out publicly and forcibly about governmental attacks on biomedical research?

Lisa Jarvis@lisamjarvis.bsky.social · last yr.

Noticeably silent amid the upheaval at HHS? Big pharma. Every new drug has NIH somewhere in its DNA--and NIH funding supports the training of their workforce. Now they're finding out FDA isn't safe, either. Wrote about how keeping quiet isn't working My latest @opinion.bloomberg.com (gift link):

Big Pharma Needs to Get Off the Sidelines

The industry can’t continue to sit idly by while Robert F. Kennedy Jr. guts the nation’s public health agencies.

bloomberg.com

Howard Liu, MD, MBA@drhowardliu.bsky.social · last yr.

“She was required, under a new return-to-office policy, to conduct virtual psychotherapy with her patients from one of 13 cubicles in a large open office space, the kind of setup used for call centers.” www.nytimes.com/2025/03/22/u... via @NYTimes

Inside the Turmoil at the V.A. Mental Health System Under Trump (Gift Article)

A chaotic restructuring ordered threatens to degrade services for veterans of wars in Vietnam, Iraq and Afghanistan.

nytimes.com

Colette Delawalla, PhD@cdelawalla.bsky.social · last yr.

HEY DORKS IN AMERICA!! If we don’t get into the streets and fight this, there will be no science left here. We don’t have time for luke warm, diplomatic takes and accusations of “taking this clown too seriously.” Put your big girl pants on and LFG.

Randy McIntosh@ar0mcintosh.bsky.social · last yr.

With a heavy heart, I've decided to suspend all academic travel to the USA for me and my lab. Given the escalation of tensions and uncertainties, it seems to be the wisest move. To our US colleagues, please be certain that we will continue to do what we can to support you. Science is global.

Brian Pace@brianpace.bsky.social · last yr.

@msmacb.bsky.social on NYT's cringey smear of @psymposia.bsky.social: “When vague accusations of ‘DEI’ and ‘wokeness’ are already being used to gut government programs, it might not be a bad time to blame the FDA’s decision on ‘a small band of anticapitalist activists.’” slate.com/technology/2...

This NYT Story Blasting Leftists Is Wildly Misleading and Dangerous. Why Did They Publish It?

Painting the FDA as easily corruptible may serve the MAHA agenda of eliminating oversight that keeps us all safe.

slate.com