Maria Antonietta Tosches

@matosches.bsky.social

Associate Professor @ Columbia University. Brain evolution, plasticity and regeneration. www.tosches-lab.com

What is a body made of? Many great studies have identified, characterized, and cataloged cell types across organisms. New in @science.org, we take this question to the scale of an entire adult vertebrate, opening organism-wide biology at single-cell resolution: tinyurl.com/3fbkwp4d; #ScienceResearch

Whole-body single-cell atlas of an adult vertebrate, Danionella cerebrum

A complete cell type transcriptome atlas of a vertebrate could promote understanding of animal cell type composition, organization, and evolution. The miniaturized, transparent, and regenerative teleo...

tinyurl.com

Barbara Finlay, who died on 12 September, championed the idea that developmental constraints dictate how evolution sculpts brains, which she used to model the timing of hundreds of events and align them across mammalian species. By @callimcflurry.bsky.social www.thetransmitter.org/evolution/re...

Barbara Finlay, ‘maverick’ of evolutionary neuroscience

Finlay, who died on 12 September, championed the idea that developmental constraints dictate how evolution sculpts brains.

thetransmitter.org

An other example of the value and beauty of fundamental biology research: we don’t always know what kind of future applications will be made possible by a basic discovery. This work in a single-celled alga open the doors to optigenetics 💡🧬

Nobel Prize@nobelprize.org · 4w ago

Peter Hegemann and Georg Nagel – awarded the 2026 medicine prize – discovered a remarkable protein, channelrhodopsin, in a single-celled alga. Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.

The answer to this question is a very loud and resounding NO. And neurobiologists don't just consider the notion of a "lizard brain" in humans misleading. It is wrong. Very wrong. The only lizard brain is that found within lizards. #neuroethology #neuroskyence www.theguardian.com/science/2026...

Do humans really have a ‘lizard brain’ lurking beneath our rational minds?

It’s a powerful analogy that captured the popular imagination, but the biological reality is quite different

theguardian.com

The Cajal Club remembers neuroscientist Barbara L. Finlay, whose pioneering research advanced our understanding of brain development, evolution, and the cerebral cortex. We honor her remarkable scientific legacy, mentorship, and friendship. #Neuroscience #Cajal www.cajalclub.org/in-memoriam-...

In Memoriam: Barbara Finlay

The Cajal Club remembers Barbara L. Finlay, an influential developmental and evolutionary neuroscientist whose pioneering research transformed our understanding of brain evolution and development, and...

cajalclub.org

There is still time to apply for the EMBL International PhD Programme! 📢 Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research. Research groups across EMBL are recruiting now! bit.ly/4x9Edss

Bild

Prebilaterian Origin of Monoaminergic Signalling is out! This paper represents four years of work, not only mine, but friends and colleagues. I am particularly grateful to Tatiana Mayorova; without her help, this paper would not have been nearly as complete. www.sciencedirect.com/science/arti...

Prebilaterian origin of monoaminergic signaling

Monoamines such as serotonin, dopamine, and tyramine regulate physiological and behavioral processes in bilaterian animals, but the evolutionary origi…

sciencedirect.com

I am excited to announce the latest paper from our lab, published in Science ! In this study, we show that thalamocortical-like circuits in the zebrafish brain process sensory information hierarchically across topographically organized forebrain circuits.

Hierarchical sensory processing in zebrafish thalamocortical-like circuits

Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian...

science.org

Kavli Institute for Systems Neuroscience@kavlintnu.bsky.social · 4mo ago

Out now in @science.org by @emreyaksi.bsky.social, Anh-Tuan Trinh and colleagues at the Kavli Institute in Trondheim: Hierarchical sensory processing in zebrafish thalamocortical-like circuits doi.org/10.1126/scie...