Our paper is now out, opioid use in rats increases microglia density, affects morphology, and it's related to brain volume changes. link.springer.com/article/10.1...

Effects of morphine self-administration on brain structure and microglial phenotypic diversity in the absence of neuronal loss in male Wistar rats - Psychopharmacology

Rationale Opioid addiction, including morphine use, is a major public health crisis in the U.S. It has been associated with brain volume changes in reward-related regions, neuronal loss, and neuroinfl...

link.springer.com

Eduardo Garza-Villarreal@egarza.bsky.social · 2y ago

New preprint from the lab: www.biorxiv.org/content/10.1... This was led by former Bachelor student Débora Elizarrarás and postdoc César Carranza. Here we wanted to study structural brain changes in opiod self-administration. Specifically if there was a link between MRI volume and neuroinflamation.

Carne asada (y vegetales) del laboratorio

Very happy to host Dr. Flavia Venetucci from @sickkidsto.bsky.social last month and to the start of a great collaboration.

Can't ask for a better team #ISAR2025

La investigación de mi alumna @aleloc.bsky.social y del laboratorio: www.jornada.com.mx/noticia/2025...

Científicos de UNAM usan estimulación magnética transcraneal contra las adicciones

A través de una bobina que se coloca sobre el cuero cabelludo se generan campos magnéticos que incentivan regiones cerebrales.

jornada.com.mx

🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘 www.biorxiv.org/content/10.1... Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇

When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...

The history and future of resting-state functional magnetic resonance imaging - Nature

This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...

nature.com

**FMRI/neuroimaging folks** Quick reminder @ the next AFNI Bootcamp: May 28-30, 2025. Learn through interactive data analysis! Day 1-2: data viz, single subject analysis and QC. Day 3: statistics, results reporting and group analysis. Details, registration and schedule: afni.nimh.nih.gov/bootcamp

Registrations are open for the 2nd International Symposium on Addiction Research (ISAR) 2025 in Querétaro, Mexico, from August 25-27. Come visit us and show your work! addictions.inb.unam.mx

PhD student from my lab, @dangeles.bsky.social just released our collaboration with @mariejosevantol.bsky.social . "First vs recurrent episode symptomatology in Major Depressive Disorder and its relation to brain function and structure: a network approach"

Diego Angeles-Valdez@dangeles.bsky.social · last yr.

Proud to share our first preprint: “First vs recurrent episode symptomatology in Major Depressive Disorder and its relation to brain function and structure: a network approach” with @egarza.bsky.social and @mariejosevantol.bsky.social Read more: www.biorxiv.org/content/10.1....

Awesome @afni-pt.bsky.social invited me to this and I think it's a great concept.

Paul Taylor@afni-pt.bsky.social · last yr.

The result of a large (42 authors!) collaboration: "Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation" arxiv.org/abs/2504.07824 TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications

Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.

nature.com

7 years ago, I received funding for a project on personality, incentivized prosocial behavior & social status in groups. Today, we've made the anonymized data publicly available. Researchers can now use it by citing the preprint/paper (no need to add anyone as a coauthor): doi.org/10.31234/osf...

People from my lab did a wonderful job on Brain Week teaching about the problems with substance use. A major effort on their part.

Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience onlinelibrary.wiley.com/doi/10.1111/... - really pleased that this paper with Henry Potter is now published in the European Journal of Neuroscience 😊

Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience

The search for neural mechanisms of behaviour often relies on a synchronic, driving view of causation, where neural activity drives more neural activity, which eventually drives behaviour. The real c...

onlinelibrary.wiley.com

New preprint from the lab: www.biorxiv.org/content/10.1... This was led by former Bachelor student Débora Elizarrarás and postdoc César Carranza. Here we wanted to study structural brain changes in opiod self-administration. Specifically if there was a link between MRI volume and neuroinflamation.

Morphine self-administration induces region-specific brain volume changes and microglial phenotypic alterations without affecting neuronal density in male Wistar rats

Addiction to opioids, including morphine, is a major public health crisis in the U.S. It has been associated with brain volume changes in reward-related regions, neuronal death, and neuroinflammation....

biorxiv.org

Scientists are called on more and more to respond to questions about their results. We tried to put down some ideas for the best ways to do that based on our years of observing these interactions. Engaging is better than not, especially when science is under attack. www.science.org/doi/10.1126/...

Breaking the silence

Research on science communication has largely focused on teaching scientists how to describe their studies in ways that interest the public while deepening their understanding of scientific exploratio...

science.org

🚀 We’re officially on Bluesky! 💙 The Women in Network Science (WiNS) Society connects and supports network scientists who identify as underrepresented genders in the field. Follow us for updates on events, opportunities, and exciting research from our community! #NetworkScience #WiNS

Hey neuroscientists: were you, your lab or any of your ongoing projects caught up in any of the latest NIH firings? You can find me on Signal at avaskham.54 if you want to chat. 🧪 #neuroskyence

New paper led by Aurelie Bussy now out in Neurobiology of Ageing Here we use non-negative matrix decomposition using morphological and qMRI measures (T1, T2*) to understand the relationship between GM and microstructure across the Alzheimer's spectrum. www.sciencedirect.com/science/arti...

Exploring morphological and microstructural signatures across the Alzheimer's spectrum and risk factors

Neural alterations, including myelin degeneration and inflammation-related iron burden, may accompany early Alzheimer's disease (AD) pathophysiology. …

sciencedirect.com

New work let by PhD student at the lab @jalilrt.bsky.social . Does chronic stress increases alcohol drinking in adolescent rats and how does that affect their behavior, brain structure and functional connectivity, and is there an effect of sex? www.biorxiv.org/content/10.1...

This is so cool!

jamanetwork.com/journals/jam... Thread below👇

Mapping Lesions That Cause Psychosis

This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit

jamanetwork.com

We are organizing a Neuroimaging Summer School with the @cervo-ulaval.bsky.social in Quebec and @ibroorg.bsky.social. LATAM graduate students will have all expenses paid. More info at the site and here q2summerschool@inb.unam.mx Calls will close April 20. q2summerschool.com ibro.org/training-opp...

It’s out! 🎉 Check our paper “Disentangling the effect of sex from brain size on brain organization and cognitive functioning” 🧠, where we explored sex differences in the brain while removing the effect of brain size differences. 1/10 link.springer.com/article/10.1...

In biomedical sciences, there is a gap in understanding how sociodemographic factors affect biological and behavioral processes, in part due to inconsistent data collection. To address this, we're surveying researchers about their sociodemographic questionnaires: forms.gle/T8EiWHNJ4UoS...

ECT, TMS, and ketamine outperform other options for treatment resistant depression. Should we be offering these options to patients earlier in the course of illness? www.nature.com/articles/s41...

Relative effectiveness of antidepressant treatments in treatment-resistant depression: a systematic review and network meta-analysis of randomized controlled trials - Neuropsychopharmacology

Neuropsychopharmacology - Relative effectiveness of antidepressant treatments in treatment-resistant depression: a systematic review and network meta-analysis of randomized controlled trials

nature.com

I was today years old when I found out that famous labs average multiple trials/blocks of fMRI data before running multiple linear regression/GLM 🤯 This breaks so many principles of statistics that one could write an entire book...

Maybe slightly odd timing, but we'd like to announce: A new AFNI Bootcamp for FMRI/MRI, Jan 29-31, 2025. This part will focus on group analysis, statistics, surface analyses, results reporting and more. This event will be virtual. Please see here: discuss.afni.nimh.nih.gov/t/afni-bootc...

AFNI Bootcamp, Part 2: Jan 29-31, 2025 (Virtual)

We are pleased to announce a new AFNI Bootcamp, taking place Jan 29-31, 2025. Registration is free and open to both NIH and non-NIH researchers. The course is aimed at people who have some familiarit...

discuss.afni.nimh.nih.gov

New collab paper with my former PhD student Said Jimenez. in BPD, we found a remarkable interrelationship between three of the core nodes of the disorder: 1) feelings of emptiness, 2) identity instability (identity diffusion), and 3) anger dysregulation. www.sciencedirect.com/science/arti...

Longitudinal dynamics between the central nodes in the symptoms network of borderline personality disorder: An intraindividual network analysis

Borderline Personality Disorder (BPD) is a severe and heterogeneous psychiatric condition. Current research has some limitations: (1) findings from gr…

sciencedirect.com