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Eric Morand

@ericfmorand.bsky.social

Professor of Clinical and Molecular Medicine at Monash University and Head of Rheumatology at Monash Health

54 Posts122 Follower 36 Folgt

Fabien VINCENT @fabozy.bsky.social · last mo.

High blood pressure is common in #SystemicSclerosis, but its causes are not always clear. Our latest study suggests that primary aldosteronism-common, treatable cause of high blood pressure-may be present in some patients, highlighting the importance of screening. rmdopen.bmj.com/content/12/3...

Assessment of markers of primary aldosteronism in systemic sclerosis and their relationships with renal and cardiovascular outcomes

Background Whether primary aldosteronism (PA), the most common endocrine cause of hypertension (HTN), contributes to HTN and cardiovascular disease burden in systemic sclerosis (SSc) has never been ex...

rmdopen.bmj.com

Eric Morand @ericfmorand.bsky.social · last mo.

Great work led by Laura Eades and Fabien Vincent @fabozy.bsky.social - hints that autoantibody specificities may have phenotypic meaning in #lupus

Fabien VINCENT@fabozy.bsky.social · last mo.

Excited to share our latest #lupus research in RMDOpen By profiling >1,600 IgA autoantibodies -understudied part of the immune system in lupus- we identified distinct immune signatures associated with lupus phenotypes & uncovered new biomarker candidates rmdopen.bmj.com/content/12/3...

Eric Morand @ericfmorand.bsky.social · 2mo ago

Happy to share a little review published in Med (Cell Press) on what myself and @sarahjones think is coming in #lupus. A lot of pathway validation via human trials is on its way to us www.sciencedirect.com/science/arti...

sciencedirect.com

The Economist @economist.com · 2mo ago

Where is the least liveable city in the world? One region’s score has taken a bigger fall than any other, according to the EIU’s annual index. Find out here

The world’s most, and least, liveable cities in 2026

See how 173 cities compare in EIU’s annual ranking

bit.ly

Riccardo Capecchi @blepiro.bsky.social · 2mo ago

Oh oh. This is huge. "...according to an ongoing FDA investigation conducted after publication, and without the knowledge of these two authors, the primary end-point assessments in nine patients were readjudicated after database lock and trial unblinding" www.nejm.org/doi/full/10....

Retraction: Jayne DRW et al. Avacopan for the Treatment of ANCA-Associated Vasculitis, N Engl J Med 2021;384:599-609. | NEJM

The two academic authors of the article by Jayne et al., Avacopan for the Treatment of ANCA-Associated Vasculitis, N Engl J Med 2021;384:599-609,1 request retraction of the article because, accordi...

nejm.org

MedPage Today @medpagetoday.com · 3mo ago

Two investigational drugs for lupus with encouraging primary phase II results yielded more good news from follow-on studies, reports at #EULAR2026 indicated. @eular.org @ericfmorand.bsky.social https://www.medpagetoday.com/meetingcoverage/eular/121621

Novel Lupus Drugs Continue to Shine in Extended Early Data

For one of the two, the benefits continue long after treatment stops

medpagetoday.com

Eric Morand @ericfmorand.bsky.social · 3mo ago

Big month for lupus trials! 2nd key trial published in The Lancet this month! This time a positive phase 3 trial of dapirolizumab...more to come! www.thelancet.com/journals/lan...

Efficacy and safety of the CD40 ligand inhibitor dapirolizumab pegol in systemic lupus erythematosus (PHOENYCS GO): a randomised, double-blind, placebo-controlled, phase 3 trial

Dapirolizumab pegol was associated with significant improvement in disease activity in patients with SLE. These findings support the further investigation of dapirolizumab pegol as a treatment option ...

thelancet.com

Eric Morand @ericfmorand.bsky.social · 4mo ago

Equally excited to share this positive trial result for TLR7/8 inhibition in cutaneous manifestations of #lupus, also confirming the key role of this pathway in IFN activation. www.thelancet.com/journals/lan...

Efficacy and safety of enpatoran, a Toll-like receptor 7/8 inhibitor, in patients with skin manifestations of cutaneous lupus erythematosus or systemic lupus erythematosus: findings from Cohort A of a...

Enpatoran showed a significant and dose-dependent effect on disease activity in participants with active cutaneous manifestations of CLE or SLE, and was well tolerated.

thelancet.com

Eric Morand @ericfmorand.bsky.social · 4mo ago

Excited to share this positive clinical trial outcome for TLR7/8 inhibition in #lupus. Breakthrough in understanding the origin of IFN signature in SLE? www.thelancet.com/journals/lan...

Enpatoran, a Toll-like receptor 7/8 inhibitor, in moderate-to-severe systemic lupus erythematosus: findings from Cohort B of a multicentre, international, double-blind, placebo-controlled dose-finding...

In this study of participants with moderate-to-severe SLE, enpatoran improved BICLA response rates versus placebo; however, the primary objective of a statistically significant dose-dependent effect o...

thelancet.com

Eric Morand @ericfmorand.bsky.social · 5mo ago

Very excited about the next instalment in revolutionising efficacy measurement in #lupus trials. First domain measure details for #TRM-SLE... stay tuned for the next domain papers and the final instrument soon! lupus.bmj.com/content/13/1...

Measurement of haemolytic anaemia in a novel treatment response measure for SLE clinical trials

Objectives To define a clinically meaningful treatment response definition for haemolytic anaemia, that will form part of a novel multidomain outcome measure for SLE clinical trials.Methods An interna...

lupus.bmj.com

The Economist @economist.com · 6mo ago

One Nation’s rise has engendered panic among traditional conservative parties in Australia. But by lurching rightwards, they will shed more progressive voters

Could One Nation soon become Australia’s most popular party?

The anti-immigrant party is dragging the Liberals rightward as well

econ.st

Eric Morand @ericfmorand.bsky.social · 7mo ago

A few weeks late, but pleased to call out this paper in which I had a role, showing that subcut anifrolumab is effective and well-tolerated in #lupus. Hopefully this leads to ex-hospital access option for this impactful drug. Onwards! acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study

Objective The multinational, phase 3, double-blind, placebo-controlled TULIP-SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate-to-severe SLE activity...

acrjournals.onlinelibrary.wiley.com

Eric Morand @ericfmorand.bsky.social · 7mo ago

Thanks to @cellpress.bsky.social Trends in Molecular Medicine for putting us on the cover! Sarah Jones and I review 10 years of progress in #lupus - we have come a long way, but have a long way to go...and we will keep working. www.cell.com/trends/molec...

Eric Morand @ericfmorand.bsky.social · 9mo ago

So proud of my amazing colleague Alberta Hoi at @monashuniversity.bsky.social for this Editorial in @thelancet.com on CAR-NK therapy for #lupus - another next big thing? www.thelancet.com/journals/lan...

Exploring CAR NK-cell therapy for refractory lupus

The treatment landscape for systemic lupus erythematosus (SLE) has shifted greatly in recent years, driven by the emergence of cell-based immunotherapies targeting pathogenic B-cell populations. Among...

thelancet.com

ARMI @armilabs.bsky.social · 9mo ago

An inspiring night celebrating leadership, discovery and collaboration at ARMI’s 2025 Ambassadors’ Dinner. With reflections from @ericfmorand.bsky.social on translating lupus research from lab to clinic, and from our own rising stars on curiosity and impact. Read more 👉 bit.ly/4o2WUsW

Eric Morand @ericfmorand.bsky.social · 10mo ago

www.theguardian.com/australia-ne... The power of education should be available to all.

First-in-family uni students should be recognised as disadvantaged or risk being left behind, report says

People without university-educated parents are 36% likely to enrol in degree, compared with 59% of students whose parents are tertiary educated

theguardian.com

The Economist @economist.com · 11mo ago

The discovery of regulatory T-cells may seem an obscure bit of biology to win such an esteemed prize. It is not. It is an excellent example of physiology leading to medicine in the way the prize’s double name alludes to

A Nobel prize in physiology for immune tolerance

The search to understand how the body keeps immunity in check

econ.st

Apoorva Mandavilli @apoorvanyt.bsky.social · 11mo ago

Icymi the first time this ran, here’s a refresher: Vaccines today are more efficient and contain far fewer stimulants to the immune system than some used decades ago www.nytimes.com/2024/12/14/h...

Are Childhood Vaccines ‘Overloading’ the Immune System? No.

nytimes.com

Guardian Australia @australia.theguardian.com · 11mo ago

As a paediatrician, I urge Australians to be guided by scientific evidence when making decisions on medications | Mike Freelander

Claims of a link between paracetamol use in pregnancy and autism have been repeatedly disproven – despite what the US administration suggests I have treated more than 200,000 patients in almost 40 years of practising medicine. Autism is a complex disorder which can present in many different ways and in a spectrum of severity. Causation is a very important consideration and, as a paediatrician, I know that parents often ask why their child has autism. Particularly in the severe end of the autism spectrum, genetic disorders can present with autistic features; for example Angelman syndrome, Smith-Magenis syndrome, Williams syndrome and many others. However, for the majority of the children who are diagnosed with autism, no cause is found. We also know that the number of children diagnosed with autism in the developed world is increasing. There are many reasons for this, not least that we are better at diagnosing it. However, in my work I often heard the question “why is my child autistic?” Continue reading...

theguardian.com

The Conversation AUNZ @aunz.theconversation.com · 11mo ago

It’s safe for pregnant women to take paracetamol at any stage of pregnancy. Here’s what the research says about the risk of autism.

It’s OK to use paracetamol in pregnancy. Here’s what the science says about the link with autism

theconversation.com

Lenore Taylor @lenoret.bsky.social · 11mo ago

www.theguardian.com/australia-ne... “We know that actually there is a link between fever and impacts on babies – not neurodivergence – but complications in pregnancies that result from unmanaged fever,”

Australian health experts warn Trump’s unfounded autism claims about paracetamol may harm pregnant women

TGA confirms drug is safe for use in pregnancy as doctors worry about effect of White House misinformation

theguardian.com

Eric Morand @ericfmorand.bsky.social · 12mo ago

So proud of my incredible @monashuniversity.bsky.social colleague Rangi Kandane-Rathnayake winning best abstract at #APLAR2025 for her work on burden of disease in #lupus. She is a star - we are using the regional power to make big strides in evidence-based decisions for lupus.

Eric Morand @ericfmorand.bsky.social · 12mo ago

So so proud of my colleague and PhD student Laura Eades presenting her work on metabolomics in #lupus at #aplar2025. Amazing work Laura, so well presented. Congrats to @fabienvincent.bsky.social too!

Fabien VINCENT @fabozy.bsky.social · 12mo ago

Proud to share Sherman's latest review on promising new treatments for #Sjogrens! 🧬 How engineered regulatory T cell therapies could help rebalance the immune system and bring relief to patients? @ericfmorand.bsky.social‬ @monashuniversity.bsky.social sciencedirect.com/science/arti...

Regulatory T cell therapy for Sjögren's Disease: From pathogenesis to targeted treatment

Sjögren’s disease (SjD) is a chronic systemic autoimmune disorder characterised by lymphocytic infiltration of the salivary and lacrimal glands, leadi…

sciencedirect.com

Eric Topol @erictopol.bsky.social · last yr.

This week's @thelancet.com cover and editorial www.thelancet.com/journals/lan...

Eric Morand @ericfmorand.bsky.social · last yr.

Happy to share this paper on a pilot definition of severe refractory #lupus - outcomes are poor. We need a data-driven way to identify patients for emerging therapies like CAR-T and TCE. Here is a first attempt - more to come! arthritis-research.biomedcentral.com/articles/10....

Prevalence and outcomes of a pilot definition of severe refractory systemic lupus erythematosus: observations from a multinational Asia-Pacific cohort - Arthritis Research & Therapy

Background Emerging therapies have the potential to be used in patients with severe refractory systemic lupus erythematosus (srSLE), but no agreed definition of srSLE exists. We evaluated a pilot srSL...

arthritis-research.biomedcentral.com

Lupus Foundation of America @lupus.org · last yr.

☀️ Sunscreen plays a vital role in protecting your skin, especially for those with lupus. Aim for a minimum of 30 SPF and remember to reapply every two hours! Explore our resource for more information: buff.ly/zqk6MI0 Staying sun safe? Comment a 🧴 if you’re keeping your skin protected this summer!

Dalila @dalilatm.bsky.social · last yr.

‘Professor Morand has elected, at the expiry of his term as Dean in early 2026, to focus on his critically important research at Monash on improving outcomes for patients with SLE’ #lupus 🙏🏻 👏🏻 Congrats Prof @ericfmorand.bsky.social www.monash.edu/medicine/new...

Professor Eric Morand appointed Sir John Monash Distinguished Professor

Hosted by Monash University's Faculty of Medicine, Nursing and Health Sciences, at the Monash University Prato Campus in Tuscany, the summit explored the theme “Enabling Technologies in Medicine”, off...

monash.edu

Andy Richter @andyrichter.co · last yr.

Stephen Colbert is a profoundly good and deeply talented man with a great staff and an excellent show. They all deserve better.

Eric Morand @ericfmorand.bsky.social · last yr.

Pleased to share a new Cellpress perspective article I had the privilege to co-author with my long-term colleague and collaborator Sarah Jones. Yes we have made progress in #lupus - but we need to do more. www.sciencedirect.com/science/arti...

10 years in lupus – progress, but not enough

Systemic lupus erythematosus (SLE, lupus) remains an enigmatic diagnosis with a poor prognosis. SLE is characterised by complex biology and heterogene…

sciencedirect.com