Haven't seen a better AI explainer than this one (even if it somewhat overstates the AI safety stuff) www.instagram.com/reel/Ddlt1kR...
Riccardo Capecchi
@blepiro.bsky.social
MD, PhD. Clinical Immunologist hidden inside an Internist. Sssshhhh. #medsky #immunosky #rheumatology
💡Alzheimer’s disease does not unfold on a single clock. 👉Our new study is out today. www.science.org/doi/10.1126/...
Prediction of mild cognitive impairment progression using time-sensitive multimodal biomarkers
Alzheimer’s disease (AD) develops silently for years before symptoms emerge, making early identification of at-risk individuals essential for prevention trials and early intervention. We tested whethe...
science.org
Confused about all this talk of compositionality in neuroscience? Read our new perspective www.nature.com/articles/s41... with authors Reidar Riveland and Alex Pouget.
The compositionality continuum as a principle for studying the neural basis of intelligence - Nature Neuroscience
Compositionality exists on a continuum of increasing complexity rather than as a binary trait. Studying its implementation in simpler biological and artificial systems is the most tractable path towar...
nature.com
One of the impressive things about Dr. Abdul M. El-Sayed, MD is that he is an author of over 100 scholarly articles, abstracts, and book chapters, including this one: SYSTEMS SCIENCE AND POPULATION HEALTH
Timothy McBride@mcbridetd.bsky.social · 2mo agoDr. Adbul El-Sayed is an MD, and has a degree from Oxford, and is a Rhodes Scholar.
Fucking hell as if receiving automated rejection letters for jobs wasn't bad enough.
Evolution and development of innate immune memory | Science Immunology www.science.org/doi/10.1126/... 🧪
Evolution and development of innate immune memory
Innate immune memory is reviewed as a life-span adaptation shaped by evolutionary origins, epigenetic-metabolic mechanisms, and the exposome.
science.org
✨August Issue✨| Featuring articles on: • TLR7 in SLE • Biomarkers in RA • IL-1 family cytokines in inflammatory diseases bit.ly/44LFQRi #Rheumsky #Medsky
Cyclosporiasis Outbreak Linked To Ancient Evil Corrupting The 7 Sacred Diarrhea Crystals https://theonion.com/cyclosporiasis-outbreak-linked-to-ancient-evil-corrupting-the-7-sacred-diarrhea-crystals/
NEW BLOG FOR YOU Google's energy consumption numbers in their new climate report are mind-blowing. 2 years ago they flipped from linear to exponential growth, and their climate impact is blowing out, too. A WILD testament to the obscene bloat and waste of GenAI: ketanjoshi.co/2026/07/01/g...
Oh oh. This is huge. "...according to an ongoing FDA investigation conducted after publication, and without the knowledge of these two authors, the primary end-point assessments in nine patients were readjudicated after database lock and trial unblinding" www.nejm.org/doi/full/10....
Retraction: Jayne DRW et al. Avacopan for the Treatment of ANCA-Associated Vasculitis, N Engl J Med 2021;384:599-609. | NEJM
The two academic authors of the article by Jayne et al., Avacopan for the Treatment of ANCA-Associated Vasculitis, N Engl J Med 2021;384:599-609,1 request retraction of the article because, accordi...
nejm.org
Ford has rehired hundreds of senior engineers after replacing them with AI backfired and has cost the company billions of dollars. AI adoption is blamed for Ford being the most recalled automaker in the U.S. with 51 recalls covering over 11 million vehicles in the first half of 2026 alone.
Review @natrevrheum.nature.com @vinuesalab.bsky.social @crick.ac.uk TLR7 in systemic lupus erythematosus: genetics and emerging therapies www.nature.com/articles/s41...
TLR7 in systemic lupus erythematosus: genetics and emerging therapies - Nature Reviews Rheumatology
Targeting Toll-like receptor 7 (TLR7) represents a promising therapeutic strategy for the treatment of systemic lupus erythematosus (SLE). This Review provides mechanistic insights into the roles of T...
nature.com
📣 Out now @naturemedicine.bsky.social 🧬🤖 👉 rdcu.be/fqasl Our automated reanalysis tool Talos enables broad adoption and delivers timely + equitable #raredisease #diagnosis at scale! ♻️ Runs monthly on >10K datasets 🎯High specificity 💰Low running costs 🤗Open source @dgmacarthur.bsky.social
Received our first issue of the print edition of The Onion and I am not disappointed!
Alright I'm done with this until I get a new computer.
News, rumors, opinions, misinformation, polarization, collective attention: can we understand their dynamics using the tools of statistical physics? Our new Physics Reports review brings together theory, models, and empirical evidence from across the field: www.sciencedirect.com/science/arti...
The physics of news, rumors, and opinions
The boundaries between physical and social networks have narrowed with the advent of the Internet and its pervasive platforms. This has given rise to …
sciencedirect.com
Foxp3: The epigenetic engineer of regulatory T cell identity | Science Immunology www.science.org/doi/10.1126/... 🧪
Foxp3: The epigenetic engineer of regulatory T cell identity
The Foxp3 transcription factor integrates cell-intrinsic and environmental contexts with epigenetic programs to establish regulatory T cell identity.
science.org
A computer worm, an online rumor and a zombie apocalypse are not the same thing. Despite that, they can share a similar mathematical skeleton: contact changes state and state changes propagate. Last essay for #ComplexityThoughts: manlius.substack.com/p/the-power-...
There’s a world I sometimes fantasize about where the breakthroughs in artificial neural networks are still inside research labs and leading to interesting scientific projects. This essay from @juangallego.bsky.social is like a bulletin from that alternative reality.
Why neural foundation models work, and what they might—and might not—teach us about the brain
These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity. But will we be able to understand them?
thetransmitter.org
Sneaking a giant screen into the flagshagger march is one of the funniest things @ledbydonkeys.org have ever done. "STAY HYDRATED" 😂🤣😂
The fate of similar rumors suggests how our news ecosystem and political environment have mutated, reports Anna Merlan. www.motherjones.com/politics/202...
How the “missing scientists” conspiracy theory went mainstream after others failed
The fate of similar rumors suggests how our news ecosystem and political environment have mutated.
motherjones.com
Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.
bioRxiv Synthetic Biology@biorxiv-synthbio.bsky.social · 6mo agoBridge recombinase enables versatile rewriting of bacterial genomes https://www.biorxiv.org/content/10.64898/2026.04.29.721476v1
Guzmán et al. discuss @jem.org work (Luff et al. rupress.org/jem/article/...) showing cell-intrinsic signals from TACI drive marginal zone B cell development from T2 B cells thru. a mechanism involving activation of the PI3K–AKT pathway & inhibition of the FOXO1-KLF2 axis rupress.org/jem/article/...
