Postdoc/staff scientist/ in computational biology and evolutionary genetics? Alex Cope is very good. I've collaborated with him for years. First author publications, all technically great, some in glam journals. A great team player and nice guy too. scholar.google.com/citations?us...

Alex Cope, PhD (he/him)@alexcope241.bsky.social · 4w ago

If anyone is looking for a postdoc/staff scientist with experience in evolutionary genetics, computational biology/bioinformatics, and/or various omics methods (RNA-seq, Ribo-seq, LC-MS/MS), I'm still looking! (1) doi.org/10.1126/scie... (2) doi.org/10.1073/pnas... (3) doi.org/10.1371/jour...

If anyone is looking for a postdoc/staff scientist with experience in evolutionary genetics, computational biology/bioinformatics, and/or various omics methods (RNA-seq, Ribo-seq, LC-MS/MS), I'm still looking! (1) doi.org/10.1126/scie... (2) doi.org/10.1073/pnas... (3) doi.org/10.1371/jour...

Introns have a hidden regulatory role! 🧬🎉 Delighted to share our latest paper showing that inefficiently spliced introns and spliceosomal proteins direct RNA methylation, engaging RNAi to silence retrotransposons and regulate gene expression nature.com/articles/s41...

Yes, I've done this. It's always a delight to work with SGD.

Saccharomyces Genome Database@yeastgenome.bsky.social · last mo.

Reminder: Authors can submit data and information about publications! Point us to novel results, datasets (we appreciate GEO accession IDs!), or other important info using SGD’s simple “Submit Data” form: www.yeastgenome.org/submitData

Where are we at on acceptable abbreviations for fluorescent proteins? Like, GFP for green fluorescent protein sure, but is mNG for mNeonGreen too much? Etc? Your strongest opinions and arguments invited.

What's the state of genomes that report on early animal / holozoan evolution? A student project in my lab on evolution of RNA-binding proteins is testing the hypothesis of a gene duplication in early metazoa, we want to look for homologs in in holozoa beyond Monosiga. @jlsteenwyk.bsky.social ?

I worked for UKRI for seven years and in my experience, the short timescales were 100% because of delays in central government. Usually because of delays in sign off by a minister; in the worst cases, due to number 10 comms teams insisting we hold back so the PM could announce it or whatever. 1/3

Kirsty Grainger @kirstygrainger.bsky.social · 2mo ago

A new TOP FIVE has just dropped. The @ukri.org TOP FIVE shortest timescales from call opening to closing. And you won't believe the winner 👀

Save the date : Seminar by Edward Wallace from the University of Edinburgh on Tuesday 12th May at 11h @ewjwallace.bsky.social @edinburgh-uni.bsky.social

How do fungi grow directionally? We think part of the mechanism involves local translation of mRNA near the tip, especially of cell wall components. Delighted to share our preprint showing that an RNA-binding protein, SsdA/Ssd1, is trafficked to the tip of growing fungal filaments.

Domenico Modaffari@dmodaffari.bsky.social · 3mo ago

Happy to share that the bulk of my PhD work is now on bioRxiv! We followed SsdA, the A. nidulans ortholog of yeast RNA-binding protein Ssd1, and found it forms motile mRNP puncta in hyphae. [1/7] www.biorxiv.org/content/10.6...

I am learning a lot from this debate about the last eukaryotic common ancestor. It's thought-provoking to have competing hypotheses and perspectives argued out there in the open. Here, the two arguments are internally consistent, yet different conclusions... so where's the wrong assumption?

Bungo Akiyoshi@bungoakiyoshi.bsky.social · 6mo ago

I appreciate the comments by Max Raas, Eelco Tromer and others on my paper published last year "Hypothesis that ancestral eukaryotes sexually proliferated without kinetochores or mitosis". However, I do not think their critiques can reject my hypothesis. For details, please read the paper. 1/n

Today's @gautamdey.bsky.social seminar on Evolutionary Cell Biology is mind-blowing in so many ways. Dinoflagellates don't have histones!?!?! And BEAUTIFUL microscopy.

We are hiring a postdoctoral researcher to investigate ribosome hibernation and activation in microsporidia using confocal microscopy, soft X-ray tomography, cryo-electron tomography, and omics approaches. If you are interested, apply here: jobs.exeter.ac.uk/hrpr_webrecr...

Happy to share that the our manuscript "Cyclin CLB2 mRNA localization and protein synthesis link cell cycle progression to bud growth" is now finally out in its final form @natcomms.nature.com www.nature.com/articles/s41... Below a short🧵 with the key findings!

Ugh...

Maria Niedernhuber@mariandrnh.bsky.social · 8mo ago

anyone got any advice on the following situation? I wrote and did a big chunk of the admin for a large MRC grant which also also awarded. I am named in the Staff breakdown on the grant as "researcher co-lead" with 100%FTE, and I am mentioned by name as "postdoctoral researcher Maria Niedernhuber"

Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...

Dissecting the molecular mechanism of chromosome segregation in the marine plankton Paradiplonema papillatum at University of Edinburgh on FindAPhD.com

PhD Project - Dissecting the molecular mechanism of chromosome segregation in the marine plankton Paradiplonema papillatum at University of Edinburgh, listed on FindAPhD.com

findaphd.com

Bungo Akiyoshi@bungoakiyoshi.bsky.social · 12mo ago

My attempt to become a professor was unsuccessful again but the diplonema tagging paper is now published in Open Biology. royalsocietypublishing.org/doi/10.1098/...

Wonderful talk by the legendary Jane Richardson today on validation of #cryoEM and #xray protein structures as part of the S2C2 modeling and validation workshop at SLAC. I continue to be amazed by how deeply she understands macromolecular geometry.

We are looking for an enthusiastic postdoc to investigate cellular dormancy and ribosome hibernation across plants, fungi, and mammals using #cryoET. If you are interested, apply here: careers.exeter.ac.uk/vacancies/66....

We had a great fungal minisymposium yesterday @edinburghbiology.bsky.social - really exciting to see the critical mass of fungal researchers here coming together. Next one January or February TBA: Email me to be added to the email list!

Thrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.

bioRxivpreprint@biorxivpreprint.bsky.social · 11mo ago

Jlp2 is an RQC complex-independent release factor acting on aberrant peptidyl-tRNA, protecting cells against translation elongation stress https://www.biorxiv.org/content/10.1101/2025.09.04.673968v1

Translon: a single term for translated regions. #Translation @natmethods.nature.com

Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited

New preprint! This work is Gabriela Fior Ribeiro's second first-author manuscript, @logantom.bsky.social's first manuscript, and is the culmination of our long-standing collaboration with @ewjwallace.bsky.social's group at University of Edinburgh. www.biorxiv.org/content/10.1...

Antifungal exposure can enhance Candida glabrata pathogenesis

Azole antifungal drugs directly inhibit lanosterol 14-α-demethylase and indirectly affect the expression of metabolic, transmembrane transporter, and cell wall organization genes in fungal pathogens. ...

biorxiv.org

bioRxiv bat signal going up. We have a big backlog of submissions. If any affiliates have time to do some screening, we (and all the authors) would be immensely grateful! 🙏

V happy with paperpile as a reference manager. Thanks @dadrummond.bsky.social for that recommentation.

Chris Wallace@chr1sw.bsky.social · last yr.

What do people use for references in Google docs/word? Coming from latex where referencing was solid, have been stung a couple of times by Google docs/zotero losing or messing up which paper each reference number points to. This is too painful to go through again. What are the alternatives?

I NEED to tell you the story of Tae Heung “William” Kim. He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease. He's a *legal permanent resident* of the United States. And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.

Absolutely loving the random ribosome dreams that appear on the #RNAbiology feed.

christine 🇵🇸@spaceneedlesgf.bsky.social · last yr.

little baby nucleus ribosome mitosis

Wellcome to bluesky @edinburghbiology.bsky.social - Edinburgh School of Biological Sciences! This feed collects the SBS folks on bluesky who I know about: bsky.app/profile/ewjw...

wellcome.org/news/can-bio...

Can bioimaging build capacity in fungi research? | News | Wellcome

Dr Elizabeth Ballou from the University of Exeter writes about her research on antifungal resistance and how bioimaging could help build capacity in fungal research.

wellcome.org

It’s actually even worse: they show it as a gel, which is pure fluorescence units, but a BioAnalyzes records as the molecules pass a single point sensor and critically _fails to normalize for different molecule speeds_ This results in a near-logarithmic overcounting of large molecules!

Tami Lieberman@contaminatedsci.bsky.social · last yr.

This is your regular reminder that the BioAnalyzer/TapeStation reports fluorescence units, not # of molecules. Left is bioA trace, and right is fragment size calculated from either read output (blue) or transformation of BioA trace (black). Fig 3 from journals.plos.org/plosone/arti...

THERE ARE TRANSMEMBRANE RNAs NOW?!?!?!? rnajournal.cshlp.org/content/31/8...