I'm looking for an enthusiastic student to join my team as a PhD candidate on archaeal genome evolution 🦠💻 Work in beautiful Utrecht, at @binfutrecht.bsky.social, an international group full of caring, amazing scientists, and with frequent cake breaks! www.uu.nl/en/organisat... Please share! 🙏

Wonderful to hear Carl Stetter reminisce on the discovery of Archaea at MBoA2026

Very happy to share our latest publication in Nat. Commun. www.nature.com/articles/s41... It was a great collaboration with @ifremer.bsky.social, @cbitoulouse.bsky.social and @pasteur.fr. We discovered a new hibernation factor in Archaea binding to the ribosome in three different conformations !

Two post-doctoral positions open in our lab. We're looking for people with expertise in molecular microbiology and/or genome-scale tools. Initially 3 yrs, posts could be extended for upto 8 yrs. If you'd like to know more about us take a look at www.graingerlab.com www.jobs.ac.uk/job/DQY475/r...

Research Fellow (Postdoctoral) at University of Birmingham

Explore an exciting academic career as a Research Fellow (Postdoctoral). Don't miss out on other academic jobs. Click to apply and explore more opportunities.

jobs.ac.uk

@ewarman.bsky.social has followed up on her discovery of bidirectional promoters in bacteria by defining their basic rules for regulation and links to gene expression noise... academic.oup.com/nar/article/...

Bidirectional promoters in Escherichia coli: regulatory rules and implications for gene expression noise

Abstract. In prokaryotes, bidirectional promoters are pseudo-symmetrical DNA sequences that stimulate divergent transcription. Ubiquitous, and far more lik

academic.oup.com

Delighted to share our new preprint: www.biorxiv.org/content/10.6... We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky

Localised activity of reverse gyrase at gene regulatory elements

DNA topoisomerases are essential enzymes found in all cells, where they regulate DNA supercoiling. Reverse gyrase (RG) is a unique type of topoisomerase that introduces positive supercoils into DNA an...

biorxiv.org

An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

Check out our paper on intricate nested interactions between viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts. Excellent collaboration with @deemteam.bsky.social, @anagtz.bsky.social and Michail Yakimov Free access link: rdcu.be/eLtCH 🧵 by @yifanzhou.bsky.social 👇

Yifan ZHOU@yifanzhou.bsky.social · 10mo ago

Our work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology! @mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social www.nature.com/articles/s41...

We have an exciting PhD opportunity to study ribosome hibernation in archaea using cryo-electron microscopy, tomography, microfluidics, omics, and confocal imaging. @daumlab.bsky.social, @lsiexeter.bsky.social Apply via: www.exeter.ac.uk/study/fundin... Any questions, IM me.

Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com www.nature.com/articles/s41... Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social

Structure of a functional archaellum in Bacteria of the Chloroflexota phylum - Nature Microbiology

Bona fide gene clusters for archaella are widespread across a bacterial phylum and encode functional motility machinery.

nature.com

Sonja-Verena Albers@archaellum.bsky.social · 2y ago

Would you expect that Bacteria use an archaellum for swimming? We didn't, but we found that some Chloroflexota do! Find the story here: www.biorxiv.org/content/10.1... A little thread below 1/n

I set out to review the evolution of eukaryotic intracellular traffic, but along the way a new hypothesis came into focus: maybe the earliest membrane carriers were tubules, not coated vesicles! New preprint: ecoevorxiv.org/repository/v... Here’s the idea. 🧵

1/16 New pre-print from the Sternberg Lab! We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here: tinyurl.com/mshwjd77

And the story is published now!🍾 www.nature.com/articles/s41... Open access link: rdcu.be/exnOc Many years in the making, great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social Thanks @ukri.org BBSRC & @leverhulme.ac.uk for funding, reviewers & editor!! 🙏 #microsky #archaeasky

Coupling chromosome organization to genome segregation in Archaea - Nature Communications

Proteins SegA and SegB are important for chromosome segregation and organization in archaea of the order Sulfolobales, but mechanisms are unclear. Here, Kabli et al. uncover patterns and mechanisms th...

nature.com

Daniela Barillà@danielabarilla.bsky.social · last yr.

New preprint from our lab! Story started long ago that took many years in the making. Great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social groups. Generously funded by BBSRC @ukri.org & @leverhulme.bsky.social How do #archaea segregate their chromosome? #microsky #archaeasky

Elated to have our pre-print now published in @natcomms.nature.com #ArchaeaSky #Microbiology #MEvoSky rdcu.be/euila Our main results stay the same: S. islandicus follows a cell cycle akin to that of some eukaryotes, like the budding yeast, with cellular processes cycling similarly. old🧵cited below👇

Transcriptional landscape of the cell cycle in a model thermoacidophilic archaeon reveals similarities to eukaryotes

Nature Communications - The cell cycle of the archaeon Saccharolobus islandicus displays similarities to that of eukaryotic cells. Here, the authors use transcriptomic analysis of synchronized...

rdcu.be

Miguel Gómez-Raya@miguelgrv.bsky.social · 2y ago

Very happy to share the first publication from my PhD as a preprint!! Are you an archaea enthusiast? A network afficionado? Do you love the cell cycle? If you answered yes to any of those questions this preprint is for you! Little 🧵 (1/11) www.biorxiv.org/content/10.1...

A must-read for histone afficionados: our new review on 'Histone-mediated chromatin organization in prokaryotes and viruses' www.cell.com/trends/bioch... @samuelschwab.bsky.social @vikramalva.bsky.social

Histone-mediated chromatin organization in prokaryotes and viruses

Histones are fundamental chromatin-organizing proteins in eukaryotes and archaea, where they assemble into (hyper)nucleosomes that wrap DNA. Recent studies have expanded the known repertoire of histon...

cell.com

We’ve uncovered Asgard chromatin structures formed by a Hodarchaeal histone : closed hypernucleosome conserved in archaea and an open form resembling the H3-H4 eukaryotic octasome. Fantastic work by @harshranawat.bsky.social! www.biorxiv.org/content/10.1... #Chromatin #Asgard #Archaea #cryoEM

In this new publication, we took #archaea for a walk in the chemical garden 😉. The abiotic hydrogen produced in this setting can fuel M. jannaschii’s metabolism. Great interdisciplinary collaboration with the Orsi lab who initiated and led this study. More here www.nature.com/articles/s41...

Simulated early Earth geochemistry fuels a hydrogen-dependent primordial metabolism - Nature Ecology & Evolution

In an iron-sulfide chemical garden experiment that mimics the kind of hydrothermal vents that might have occurred in the early Archaean, mackinawite and greigite are precipitated and abiotic H2 is pro...

nature.com

The MIMIC lab is hiring a Postdoctoral Research Associate to join my team at @Cambridge_Uni! Exploration and engineering DNA-mimicking proteins (wet-lab position.) 🧬 Details: www.jobs.cam.ac.uk/job/50652/ Please get in touch / circulate !

www.findaphd.com/phds/project... A funded PhD studentship is available for a joint project between my lab and @andreashaag.bsky.social @uniofstandrews.bsky.social

Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews on FindAPhD.com

PhD Project - Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews, listed on FindAPhD.com

findaphd.com

New preprint from our lab! Story started long ago that took many years in the making. Great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social groups. Generously funded by BBSRC @ukri.org & @leverhulme.bsky.social How do #archaea segregate their chromosome? #microsky #archaeasky

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · last yr.

Coupling chromosome organization to genome segregation in Archaea https://www.biorxiv.org/content/10.1101/2025.02.07.637068v1

📢 New round of PhD studentships. Open to applicants worldwide. 📅 Deadline 14th March www.findaphd.com/phds/project... #microsky #archaeasky #chromosome 🧬🧬🧬 @steve-quinn-lab.bsky.social @georgerheath.bsky.social Join us in beautiful York, UK!

Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York on FindAPhD.com

PhD Project - Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York, listed on FindAPhD.com

findaphd.com

If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)

Interested in the complexity of gene expression in Archaea? We have three open postdoc positions focussing on the coupling of transcription and translation using functional genomics, structural biology and molecular biology in Finn Werner's lab at UCL. Links below!