⏳ Deadline Jan. 14 (11:59 PM MST)! Submit abstracts/apply for scholarships for Tumor Microenvironment / Inflammation Resolution. 🔗 keysym.us/KSTumorMicro26 | keysym.us/KSInflammati... @coussenslab.bsky.social @sandramcallister.bsky.social @laurakiessling.bsky.social @magarianblander.bsky.social

Cassiar, BC, was an idyllic place to grow up. More than 30 years after the asbestos mine closed, some former residents believe their cancer diagnosis is linked to their time there — and they struggle to find supports. First in a two-part @thetyee.ca series: thetyee.ca/News/2026/01...

The Town That Asbestos Built. The Cancer It Left Behind | The Tyee

Former residents of Cassiar say they weren’t warned about the risks. Now, they struggle to find support.

thetyee.ca

Can never repost this 2025 finding enough: 91,000 deaths EVERY YEAR in the United States are caused by air pollution from oil and gas. That’s 250 funerals a day That’s the human sacrifice required for running our economy via extracting and burning fossilized Devonian corpses You good with that?

Dr. Sandra Steingraber 🏳️‍🌈@ssteingraber1.bsky.social · 7mo ago

Your reminder that fossil-fuel related air pollution kills 91,000 American every year. climate crisis = health crisis www.science.org/doi/10.1126/...

The US Department of Agriculture has ordered that "states must immediately undo any steps taken to issue full SNAP benefits for November 2025".

Can better understanding misogyny stop gun violence? @bradgage.bsky.social talks to extremism expert and Man Up author @milleridriss.bsky.social for the Real Feels podcast:

Can Understanding Misogyny Stop Gun Violence? - With Cynthia Miller Idriss

Podcast Episode · Real Feels - Modern Masculinity with Brad Gage · 10/28/2025 · 36m

apple.co

Online now: TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells

TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells

Memory CD8+ T cells can undergo TCR-dependent or -independent activation. Here, Lee et al. show that IL-15-induced bystander activation of human memory CD8+ T cells is suppressed by concurrent TCR signaling through NFATc1-AP-1 interactions. Furthermore, they validate a bystander activation gene set induced by IL-15 and decreased upon TCR stimulation.

dlvr.it

www.nature.com/articles/s41... PDF www.nature.com/articles/s41...

Phagocytosis: a process that shapes immune responses to engulfed meals - Nature Reviews Immunology

In this Review, Li and Underhill discuss recent advances in understanding the process of phagocytosis. The authors highlight how phagocytosis is integral for innate immune sensing and explain how the ...

nature.com

excited to read this preprint from rabinowitz lab- how does the body decide which nutrients are burned, and how can this go wrong in T2 diabetes? www.biorxiv.org/content/10.1...

Competitive catabolism in systemic metabolic homeostasis

Systemic metabolic homeostasis maintains circulating nutrient concentrations within physiological ranges. Insulin is central to this process, lowering circulating levels of glucose, free fatty acids, ...

biorxiv.org

Every time someone says “We DoNt kNoW hOw To Do GoOd ScICoMm!” a meteorologist loses their wings**. **shit

"43% drop in peanut allergies" Good example of how science evolves. And "how a public health recommendation can change children’s health.” And how good research (support, pls) informs policy. Peanut Allergies Have Plummeted in Children, Study Shows www.nytimes.com/2025/10/20/w...

Peanut Allergies Have Plummeted in Children, Study Shows

nytimes.com

Oh here’s another hill I like to die on. No outdoor cats. If you have outdoor cats you’re a self absorbed asshole and should not be allowed to have pets.

Zach Weinersmith@zachweinersmith.bsky.social · 10mo ago

Do you have any extremely niche, but serious, ethical stances?

Meanwhile in the UK "Do you think it was wrong to leave the EU?" "Yes." "And yet you would vote for the people who told you leaving the EU is a good idea?" "Sure, why not?"

Our newest publication is out, and it is most certainly a colorful one!! Using carefully controlled experiments in keratinocytes, we show that different light wavelengths affect cell metabolism and integrity in different manners. febs.onlinelibrary.wiley.com/doi/10.1002/...

For day 12 of #spacetober_challenge prompt eclipse: #mathematician & #astronomer Nicole-Reine Lepaute (1723-1788) and her calculated path of the solar eclipse of 1764. 🧪🐡👩🏼‍🔬🧮🔭 #histsci She also worked with Alexis Clairaut & Jérôme Lalande to precisely calculate the date of return of Halley’s Comet, 🧵

Awesome public health news: Maldives becomes the first country to achieve ‘triple elimination’ of 1. mother-to-child transmission of HIV, 2. Syphilis and 3. Hepatitis B www.who.int/news/item/13...

Maldives becomes the first country to achieve ‘triple elimination’ of mother-to-child transmission of HIV, syphilis and hepatitis B

In a landmark public health achievement, WHO has validated the Maldives for eliminating mother-to-child transmission (EMTCT) of hepatitis B, while maintaining its earlier validation (in 2019) for EMTCT of HIV and syphilis. This makes the Maldives the first country in the world to achieve ‘triple elimination’.

who.int

Remarkable recovery of the Klamath River salmon. Many thanks to the agencies, Tribes, and NGOs who came together to remove dams and monitor the recovery of the Klamath River salmon. And kudos, too, to the indigenous youth who paddled source to sea on the newly freed river

Jennifer Molidor@jennifermolidor.bsky.social · 10mo ago

Hanging onto every bit of good news The river has come alive in the Klamath with wild Chinook salmon. The wider ecosystem is healing. This most powerful story of Indigenous-led #rewilding after the largest dam removal in US history keeps getting better. lostcoastoutpost.com/2025/oct/9/o...

I am open to the idea that there are people who don't have and don't want to gain the skills to engage directly with their data but every single day that I do I learn the answer to a question you'd never even think to ask unless you were personally staring into the abyss of an uncleaned dataset.

Genuinely thrilled to share our new story with the world - an amazing collaboration with @profsharona.bsky.social and Bill Zagotta using their innovative FRET technique to study mitofusin conformational changes. Huge credit to Sophie Hurwitz for tackling this project. urldefense.com/v3/__https:/...

Structural insights into GTP-coupled conformational changes in Mfn1 revealed by time-resolved transition metal ion FRET.

Outer mitochondrial membrane fusion is mediated by the mitofusin paralogs Mfn1 and Mfn2. Nucleotide-driven self-assembly and conformational changes are required for regulated membrane fusion activity,...

urldefense.com

Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here: www.biorxiv.org/content/10.1...

Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells

Tissue-resident memory CD4+ T cells (TRM) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ TRM...

biorxiv.org

The Venezuelan opposition leader was forced to go into hiding in 2024 after being banned form standing in that year’s election.

Nobel peace prize winner Maria Corina Machado: Venezuelan opposition leader forced into hiding after taking on Maduro

The Venezuelan opposition leader was forced to go into hiding in 2024 after being banned form standing in that year’s election.

tcnv.link

Immigrant scientists make a massive contribution wherever they go More than 30% of this century’s science Nobel prizewinners immigrated www.nature.com/articles/d41...

More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys

The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.

nature.com

"We're doing the studies to make the proof." This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.

Aaron Rupar@atrupar.com · 10mo ago

RFK Jr on Tylenol and autism: "It is not proof. We're doing the studies to make the proof."

Implantation is inherently a mechanical process. We find contractility is necessary and sufficient for spreading behaviors. We can artificially age embryos from young females and even rescue aged embryo spreading just by tuning contractility!

THIS IS THE WAY. Everyone gets their knickers in a twist when I say we can’t sci-comm our way out of this mess…but maybe you’ll listen to the more eloquent and measured @edyong209.bsky.social! This isn’t happening because people don’t appreciate the brilliance of the double helix structure.

Science Vs@sciencevs.bsky.social · 10mo ago

This moment from our latest episode with science writer @edyong209.bsky.social is 🔥 We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪 Listen wherever, or watch on Spotify 👇 open.spotify.com/episode/7Evh...

The remarkable number of people, me included, who were inspired by her work, life and example is the biggest tribute. Find a way to honor her memory. The wolrd is a bit smaller and sadder with her gone

The Guardian@theguardian.com · 10mo ago

Jane Goodall, world-renowned primatologist, dies aged 91

The language of non-consent around AI is really telling. "It's too late to be scared." "It's here whether we want it or not." "You'll have to learn to work with it." "You can't fight the inevitable." All just variations of "you're not allowed to say no." Creepy technology made by creepy people.

The Guardian@theguardian.com · 10mo ago

‘It’s too late to be scared’: readers on the controversial rise of AI ‘actors’

"In 2012, 60 trans-related articles were published by Britain’s media. By 2022, it was more than 7,500, according to figures from Trans Media Watch. The media is not responding to public rage against vulnerable minorities; it is helping to create it." www.prospectmagazine.co.uk/politics/709...

What is a reactionary centrist, and does the UK have them?

A term favoured by US progressives can help us understand Britain’s drift to the right

prospectmagazine.co.uk

Check out this new thermo-hot paper from the @colllab.bsky.social Lab. Glad to contribute and work with her team. www.biorxiv.org/content/10.1...

NLRP3 is a thermosensor that is negatively regulated by high temperature

Inflammation is an essential response to infection and injury, but unregulated inflammation is damaging and must be limited by negative feedback signalling. Inflammasome signalling drives local inflam...

biorxiv.org

Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data www.nature.com/articles/s4...

"Almost 200 Cardiff University staff members left in limbo as they face losing jobs | Wales Online"

Almost 200 Cardiff University staff members left in limbo as they face losing jobs | Wales Online

Cardiff University confirmed it cannot rule out compulsory redundancies as it also apologised to students for problems with a new timetabling system as the academic year begins

bit.ly