Major PhysiCell paper in Cell using a new, intuitive model grammar to create complex multicellular systems models with "plain language" cell hypotheses! 🧪 @cellpress.bsky.social @cp-cell.bsky.social @mathcancer.bsky.social @fertiglab.bsky.social #mathonco #mathbio #abm #opensource

Paul Macklin@mathcancer.bsky.social · last yr.

Really excited to share our new @cellpress.bsky.social Cell paper with @fertiglab.bsky.social and colleagues. 1/n www.cell.com/cell/fulltex... @jktgfoundation.bsky.social @itcrtraining.bsky.social @smbmathbiology.bsky.social #mathbio #mathonco @mathonco.bsky.social @deniswirtz.bsky.social

Excited for this @cp-cell.bsky.social article co-led by @fertiglab.bsky.social and Genevieve Stein-O'Brien, on creating a plain language "grammar" to easily write simulation models as virtual laboratories for complex systems like cancer. Fully open access and open source! 🧪 #mathonco #mathbio

Cell - a Cell Press journal@cp-cell.bsky.social · last yr.

Now online! Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

Really excited to share our new @cellpress.bsky.social Cell paper with @fertiglab.bsky.social and colleagues. 1/n www.cell.com/cell/fulltex... @jktgfoundation.bsky.social @itcrtraining.bsky.social @smbmathbiology.bsky.social #mathbio #mathonco @mathonco.bsky.social @deniswirtz.bsky.social

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

We developed a plain text modeling language—a cell behavior hypothesis grammar—to easily build virtual cell models and connect them to data, helping scientists to unlock the hidden dynamics of tissues...

cell.com

#AACR25 #AACR2025 @theaacr.bsky.social following the plenary session, at 10:15 in S105, we will showcase possible means to preventing cancer onset by intercepting its #TME @fertiglab.bsky.social #BarbaraVanderhyden and yours truly

Researchers at UMSOM are pioneering a new approach to precision medicine by combining AI with mathematical modeling.🌟🔬 @fertiglab.bsky.social and @genomescience.bsky.social colleagues share the importance of ethically sharing health data to ensure reproducible and trustworthy scientific outcomes.

Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík! Apply here: tinyurl.com/34y6jcrd #epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency

Call it what it is: a race/ gender purge.

The Washington Post@washingtonpost.com · last yr.

Thirty-eight of 43 experts cut last month from the boards that review the science and research that happens in laboratories at the National Institutes of Health are female, Black or Hispanic, according to an analysis by the chairs of a dozen of the boards.

Virtual cells for predictive immunotherapy - @fertiglab.bsky.social @genomescience.bsky.social go.nature.com/4jfqM3Y

Proud of our new perspective describing the role of mathematical biology for immunotherapy www.nature.com/articles/s41... @natbiotech.nature.com

Any mamma of a kid with autism knows exactly where a quick claim of its cause / blame will go…..

Dr. Lucky Tran@luckytran.com · last yr.

Science does not work like this. The only way you can set a timeline is if you have rigged the results in advance.

Omg!!!! So proud of my baby cousin!!!!!!

Musical Theatre Review@musicaltheatrer.bsky.social · last yr.

No sinking feeling for Titanique tonight. The show currently running at the Criterion Theatre, has won the award for Best New Entertainment or Comedy Play! @olivierawards.bsky.social

Unexpected treat today @moffittnews.bsky.social Innovator's of Tomorrow symposium with Jeanette Johnson, working with @fertiglab.bsky.social and developing on @physicell.bsky.social to create an #ABM for #pancreatic #cancer forecasting

as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech bsky.app/profile/need...

Yours in negritude, Ryan K. Smith@mewefree.bsky.social · last yr.

Looks like we've got a cure for sickle cell. www.cbsnews.com/newyork/news...

Homecoming seminar @ummedschool.bsky.social

Thank you to the #EACR!

Johanna Joyce@johannajoyce.bsky.social · last yr.

Cancer knows no borders, and setbacks in one part of the world can have lasting consequences for #patients everywhere The #EACR, and all co-signing national #cancer societies & foundations, stand in solidarity and offer our full support to our friends and colleagues in the US #StandUpForScience 🧪

Cancer knows no borders, and setbacks in one part of the world can have lasting consequences for #patients everywhere The #EACR, and all co-signing national #cancer societies & foundations, stand in solidarity and offer our full support to our friends and colleagues in the US #StandUpForScience 🧪

EACR - European Association for Cancer Research@helloeacr.bsky.social · last yr.

The EACR stands against threats to cancer research. Protecting scientific research is vital for progress and and the development of new treatments. Read our full statement in support of our friends and colleagues in the US: eacr.org/statement-on...

Cleveland on the Ukraine invasion anniversary

Kendra "Gloom is My Beat" Pierre-Louis@kendrawrites.com · last yr.

I still see a lot of ukranian flags/we stand for ukraine signage in my very not Ukranian neighborhood.

I am ashamed to be an American today. I stand with Ukraine. I stand with Canada. I stand with Panama. I stand with Greenland. I stand with Europe.

My kids thoughts and our hearts to everyone at NOAA @benfertig.bsky.social

🧬 We Want Your Feedback! 🧬\ Do you use variant annotation software? We’re gathering insights from the genomics community to improve OpenCRAVAT and understand what features matter most to you.💡 Take this quick survey (it takes less than 2 minutes!): https://shorturl.at/iOvMt

Heatbreaking. Absolutely heartbreaking

Dr. Larissa@rissarwx.bsky.social · last yr.

All probationary federal employees at NOAA’s EMC that’s responsible for keeping all US weather model systems running have been fired with 1 hours notice. And that includes me and colleagues. We will not go quietly because we care about the NOAA mission to protect the public.

We asked J. Moffitt, M. Li, Q., K. Kanemaru, S. Teichmann, D. Dar, S. Itzkovitz, R. Vento-Tormo, @ltkagohara.bsky.social @itaiyanai.bsky.social @fertiglab.bsky.social @fabiantheis.bsky.social about bottlenecks facing Spatial Transcriptomics www.cell.com/cell-systems/abstract/S2405-4712(25)00033-X

What is the main bottleneck in deriving biological understanding from spatial transcriptomic profiling?

Image-based approaches to single-cell transcriptomics offer the exciting ability to directly image gene expression at the transcriptome scale within intact tissue slices, defining, discovering, and ma...

cell.com

Karchin Lab at Johns Hopkins is excited to announce a postdoctoral position focused on developing innovative methods in computational immuno-oncology. Great opportunity if you are passionate about advancing cancer immunotherapy and bioinformatics. Learn more/apply: karchinlab.org/join-us/

Contributions from: Jeffrey Moffitt, @drmingyaoli.bsky.social, Qing Nie, Kazumasa Kanemaru, Sarah Teichmann, Daniel Dar, @ltkagohara.bsky.social, Shalev Itzkovitz, Roser Vento-Tormo, @fertiglab.bsky.social, @fabiantheis.bsky.social

Today Federal Court Extends block on NIH Indirect cost cuts but final decision date unknown. The bigger problem is the Federal Register blackout, no scientific review/council meetings means no new research awards can be released from now on. 🧪 #AcademicSky www.the-scientist.com/federal-cour...

Federal Court Extends Block on NIH Funding Cuts

NIH’s plan to reduce indirect funds faced immense backlash from researchers. A federal judge ruled to extend the halt to cuts until a final decision is made.

the-scientist.com

A truly depressing article in #Nature listing of all the damage done to #science in the US by the Trump administration in just one month 💔 for so many friends and colleagues there #solidarityforscience 🧪 www.nature.com/articles/d41...

The AACR is deeply concerned that the Administration’s recent actions are threatening NIH and its mission to accelerate progress for patients with cancer and other diseases that afflict millions of Americans. Read our statement: https://buff.ly/4gRXNB8

Do you want to do something about the chaos happening at the federal level? Have you considered calling but are unsure what to say? Have you never called and find it intimidating? I'm going to write a short HOW-TO to help! The more of us that call, the more effect we have! A short thread! 1/

AACR urges Congress to reaffirm its long history of steadfast and bipartisan support for medical research by ensuring that NIH has all of the resources needed to advance its lifesaving mission to prevent, diagnose, and treat cancer and other diseases: AACR.org/NIH

AACR Legislative Action Center

Directly contact your elected officials about the importance of cancer research, the need for continued funding and the latest lifesaving breakthroughs. In the United States, you can do so by sending ...

aacr.org

American Association for Cancer Research (AACR)@theaacr.bsky.social · last yr.

The AACR is deeply concerned that the Administration’s recent actions are threatening NIH and its mission to accelerate progress for patients with cancer and other diseases that afflict millions of Americans. Read our statement: https://buff.ly/4gRXNB8