Major PhysiCell paper in Cell using a new, intuitive model grammar to create complex multicellular systems models with "plain language" cell hypotheses! 🧪 @cellpress.bsky.social @cp-cell.bsky.social @mathcancer.bsky.social @fertiglab.bsky.social #mathonco #mathbio #abm #opensource

Paul Macklin@mathcancer.bsky.social · last yr.

Really excited to share our new @cellpress.bsky.social Cell paper with @fertiglab.bsky.social and colleagues. 1/n www.cell.com/cell/fulltex... @jktgfoundation.bsky.social @itcrtraining.bsky.social @smbmathbiology.bsky.social #mathbio #mathonco @mathonco.bsky.social @deniswirtz.bsky.social

Nice writeup of our new @cp-cell.bsky.social article on an intuitive, plain language "grammar" to make simulation modeling of complex multicellular systems more accessible. Huge thx to Forest Ray and @genomeweb.bsky.social ! Joint work by @fertiglab.bsky.social, Genevieve Stein-O'Brien & team! 🧪

GenomeWeb@genomeweb.bsky.social · last yr.

Computational Model Predicts Tissue-Specific Cell Activity Over Time

Today’s morning plenary and John Jungck Prize lecture is from @smbmathbiology.bsky.social former president, Fred Adler (@dendroicap.bsky.social) on "Education, Bureaucracy and Corruption". He manages to discuss some of his virus work with former @mathonco.bsky.social member Anna Miller! #SMB2025

Hello, #SMB2025! If you’d like PhysiCell stickers, please find Paul Macklin (@mathcancer.bsky.social). I’ll try to get stickers to Randy Heiland ( @rheiland.bsky.social ) and John Metzcar (@jmetzcar.bsky.social) as well.

Really fantastic ECM and spheroid modeling in @physicell.bsky.social. Great work! 🧪

Fabian Spill@fabianspill.bsky.social · last yr.

Congrats Margherita for her new paper, where she investigated how cancer spheroids grow in collagen matrices with varying stiffness, implementing varying ECM properties in @physicell.bsky.social Thanks Tom Susan John and Pradeep for the collaboration www.frontiersin.org/journals/bio...

"Patients should be their own control" - great & pithy takeaway from @sandyanderson.bsky.social in his talk on the adoption of adaptive therapies in the clinic #SMB2025 #MathOnco

Unexpected treat today @moffittnews.bsky.social Innovator's of Tomorrow symposium with Jeanette Johnson, working with @fertiglab.bsky.social and developing on @physicell.bsky.social to create an #ABM for #pancreatic #cancer forecasting

Congrats Margherita for her new paper, where she investigated how cancer spheroids grow in collagen matrices with varying stiffness, implementing varying ECM properties in @physicell.bsky.social Thanks Tom Susan John and Pradeep for the collaboration www.frontiersin.org/journals/bio...

Frontiers | A hybrid computational model of cancer spheroid growth with ribose-induced collagen stiffening

frontiersin.org

New paper for new PhysiCell capabilities! John Metzcar et al. (2025) created a very accessible framework to integrate ECM structure into cell agent behaviors, particularly including contact guidance. Give it a look! 🧪

Paul Macklin@mathcancer.bsky.social · 2y ago

Congratulations to John Metzcar for his new paper modeling cell-ECM interactions in @physicell.bsky.social ! 🧪 This work helps provide an accessible means to have an intermediate level of ECM detail (density, orientation, anisotropy) affect cell migration and behavior. dx.doi.org/10.1007/s115...

PhysiCell 1.14.2 is released! 🧪 * bug fixes * better support for the cell behavior grammar / rules * prep work for future PhysiGym * new script to more easily add PhysiCell Studio See download links at: physicell.org/Downloads.html

Continuing our 10-year celebration of PhysiCell with some more project history! :-) Today we'll talk about choosing a name 🧪 On Thanksgiving Day in 2014, I was with family at Disneyland sitting for the parade. I'm not as super big into the parade, so I started searching for our project name ...

Another nice benefit of our approach is that we can combine the model grammar with graphical interfaces to easily write and test new models without writing code. This opens the world of simulation modeling to new communities. (Preprint by @rheiland soon!) 16/19

New in our PhysiCell Ecosystem series is a GUI for building, simulating, and visualizing PhysiCell models. PhysiCell Studio: a graphical tool to make agent-based modeling more accessible doi.org/10.46471/gig... See also the introductory video: youtu.be/jkbPP1yDzME?...

PhysiCell Studio: a graphical tool to make agent-based modeling more accessible

PhysiCell Studio: a graphical tool to make agent-based modeling more accessible

doi.org

I'm so thankful for this post! I saw it just as two different collaborators were asking us to do things with our ABMs that we hadn't done before. Your tutorials and demos were so clear! Coupling with MaBoSS and PhysiCell Studio is also great and intuitive!

Start&Stop - a PhysiCell and PhysiBoSS 2.0 add-on for interactive simulation control https://www.biorxiv.org/content/10.1101/2024.12.13.628298v1

At the #Hanami High Level Symposium, my friend and colleagues Adam Smelko is presenting our new @PhysiCell formulation that allows for stretchable cellular membrane! We are still working on this, but I hope we will be able to give you updates vero soon!

A fun FYI: PhysiCell was first publicly presented in 2015, with first open source release in 2016. So let's call 2025 our 10th anniversary! 🧪

My lectures are freely available on YouTube: www.youtube.com/playlist?lis...

Nonlinear Dynamics and Chaos - Steven Strogatz, Cornell University - YouTube

This course of 25 lectures, filmed at Cornell University in Spring 2014, is intended for newcomers to nonlinear dynamics and chaos. It closely follows Prof. ...

youtube.com

Welcome to the Science feed! Please read our FAQs for instructions for how to be added as a contributor: bossett.io/science-feed/ Mod introductory posts linked below⬇️ Use the test tube emoji on posts you want to appear in the feed🧪 Please like the feed and make sure you follow our feed rules:

Fantastic new paper by @fordversyptlab.bsky.social lab using @physicell.bsky.social !! 🧪

Ashlee N. Ford Versypt@fordversyptlab.bsky.social · 2y ago

Our newest paper is now online. Mohammad Aminul Islam, Ph.D. developed this followup to our earlier COVID-19 agent-based model and resulting lung fibrosis. Here, we studied COVID-19 with the renin-angiotensin system and patient-specific differences: www.sciencedirect.com/science/arti...

PhysiCell 1.14.1 is released! This introduced asymmetric cell division (thanks, @danielrbergman.bsky.social!), improved handling of conserved cell contents in phagocytosis and transformation, and numerous bug fixes. 🧪 #mathbio #mathonco #opensource github.com/MathCancer/P...

Release 1.14.1 · MathCancer/PhysiCell

PhysiCell: an Open Source Physics-Based Cell Simulator for 3-D Multicellular Systems Versions: 1.14.0 - Release dates: 15 September 2024 - 1.14.0 : 15 September 2024 1.14.1 : 13 December 2024 Ove...

github.com

PhysiCell 1.14.0 is released! Key features include improved cell behavior grammar (including better phagocytosis, effector attack, and cell damage), better initialization, and more! 🧪 Release notes and downloads: github.com/MathCancer/P...

Release Version 1.14.0 · MathCancer/PhysiCell

PhysiCell: an Open Source Physics-Based Cell Simulator for 3-D Multicellular Systems Versions: 1.14.0 - Release dates: 15 September 2024 - 1.14.0 : 15 September 2024 Overview: PhysiCell is a flex...

github.com

PhysiCell is now on BlueSky! 🧪 bsky.app/profile/phys...