How do phosphorylation and palmitoylation talk to each other? 🤔 Our new preprint identifies #phosphorylation of Kv4.3 as a priming event that promotes channel #palmitoylation and shapes channel activity. A fascinating example of PTM cross-talk in the heart. ❤️⚡ doi.org/10.64898/202...
A phosphorylation‑dependent mechanism controls splice variant-specific S‑palmitoylation of cardiac Kv4.3
S-palmitoylation modulates the activity of many cardiac ion channels, yet the upstream signals that control this post-translational modification (PTM) are poorly defined. Here we identify a phosphoryl...
doi.org
You know you’re old when the family group chat erupts at the possibility of the Mexico-England game being brought forward #sleepisgood
News of England taking the lead against Congo has reached the House of Lords, and the steel bill
There must be a compound German word for this feeling of seeing Germany go out on penalties….
For my 30th birthday, my lab members bought me a copy of The God Delusion. I found it (the book) sexist, patronising, and other (then) unfashionable things. For my 50th, my lab members bought me champagne and a super cute necklace. I consider this excellent progress!
The House of Commons Education Committee is out today with a report on Higher Education... I'm quoted four times! There's a lot of good meat in there, even if I think the recommendations don't meet the case. But the policy disaster is very clear. (1/2) committees.parliament.uk/work/9012/hi...
“A very serious problem”: No clear government plan for universities risking insolvency, MPs find in new report - Committees - UK Parliament
Today MPs on the Education Committee warn that the government has no clear plan for universities facing insolvency and that protections for students are inadequate, as the Committee publishes a new re...
committees.parliament.uk
A no from BBSRC with nothing but positive feedback after excellent reviews. Strong prelim data, excellent rebuttal, excellent application. But no funding. Time to consider moving to a country that takes science funding seriously? So disappointed 😔
Job alert! We are seeking a rodent in vivo electrophysiologist to work on coordination between anterior thalamus and hippocampus in rats using Neuropixels. Beautiful Scotland, leading university (Glasgow) and vibrant intellectual setting. Post is 23 months but hopefully extensible. Details here 👇
Ref definitely had too much influence on the game. Ah well. #ncfc
Take a look at Martin’s new preprint on discovering a FANCD2-interacting motif, and his helpful summary posts!
Martin Rennie@martinrennie.bsky.social · 5mo agoExcited to share our new paper uncovering how FANCD2 recognises various DNA repair proteins www.biorxiv.org/content/10.6... @hw1o9.bsky.social
Actually hilarious! I got “cute cats making cookies is the biggest betrayal of the Brexit mandate”. Seems about right.
Martin Nicholls@martinnicholls.bsky.social · 5mo agoIn honour of the Sunday Telegraph's editor and offical maddest columnist, we have created the Allister Heath headline generator... stirring-fox-7e1fab.netlify.app
I cannot believe how exciting it is watching people go down an ice slide headfirst 🤣
📚New Episode📚 A forty-year slow-motion disaster in higher education is reaching its climax – and Labour is left holding the bag. @gsoh31.bsky.social joins @rostaylor.bsky.social & @hannahfearn.bsky.social to ask if the problems can be solved ➡️ linktr.ee/ohgodwhatnowpod
www.theguardian.com/commentisfre...
So the Epstein scandal is about politics? Silly me for thinking it’s about the mass abuse of women and girls | Marina Hyde
Obsessing over individual players and political chaos leaves less time to focus on the misogyny. And that’s for the best, isn’t it guys, says Guardian columnist Marina Hyde
theguardian.com
As of roughly half an hour ago, I am now the parent of an adult 😱 Where does the time go?!
Am spending my Saturday reading grant proposals and feeling such pessimism about the state of uk science funding. So many good ideas, so many talented researchers, so incredibly little investment 😞
Ever wondered what Integrated Protein Analysis www.gla.ac.uk/colleges/mvl... actually is? Well, wonder no more as here is Mads to explain what it is and how it supports your research: www.youtube.com/watch?v=Ct3a...
Integrated Protein Analysis Webinar | Shared Research Facilities at the University of Glasgow
YouTube video by UofG MVLS
youtube.com
this is not behavior becoming of a FIFA Peace Prize recipient.
Having no racist politicians on #imaceleb this year really improved it
⏰ Only 1 week left! Registration for #DRRSC26 closes soon - don’t miss out on being part of this exciting conference. 📅 Deadline: 25 November 2025 Click here to Register: bit.ly/49oHUCi #FusionStructuralMolBio #FusionDNA
Don’t forget to apply for the 2026 Erice Course! Deadline is 30th November 2025. Apologies if earlier today I wrote Dec 15th.
Pietro Roversi@pietro1968.bsky.social · 11mo agoErice Structural Biology Course 2026 (29 May–6 Jun): apply! Train in Cryo-EM, Cryo-ET & ML to study macromolecular assemblies in cells. Hands-on + theory for next-gen structural cell biology. 🔗 erice2026.azuleon.org/application.... #CryoEM #CryoET #MachineLearning #StructuralBiology #CellBiology