New preprint on spatial AIRR here 👇 Great accomplishment by @schuckjonas.bsky.social and many others. This is the bioinformatic basis for ongoing biological discovery projects in tumor immunology. @loewe-fci.bsky.social @trr417.bsky.social

Jonas Schuck@schuckjonas.bsky.social · last mo.

🚀 Excited to share our LongAIRR preprint on bioRxiv! LongAIRR is an open-source toolbox for consistent annotation of spatially resolved long-read adaptive immune receptor repertoires, supporting Visium V1 and Visium HD 3' datasets. 📄 www.biorxiv.org/content/10.6... 💻 github.com/AGImkeller/L...

Thank you for inviting me to this wonderful retreat! I enjoyed the scientific exchange!

Frankfurt Cancer Institute@loewe-fci.bsky.social · 4w ago

✨FCI at the GSH Retreat! It was great to see so many FCI colleagues taking part in two days of inspiring scientific exchange and networking. Thanks to Martin Sebastian and Katharina Imkeller for their excellent presentations, and to the Georg-Speyer-Haus for organizing such a wonderful retreat!

🚨 Deadline extension: Register until July 10 for the #FrankfurtCancerConference 2026! ✨ Highlights: 9 scientific sessions, 32 excellent speakers, short talks, posters, lots of time to connect! 👇 Check out our program and register here: www.frankfurtcancerconference.org

✨ Introducing the speakers of our #DrugDesign sessions at the #FrankfurtCancerConference 2026 – Part 1: ▫️Gerald Crabtree ▫️Sine Reker Hadrup ▫️Michael Hölzel 📆 Sep 2–4, Frankfurt 🔗 www.frankfurtcancerconference.org 👉 Deadline: June 25, 2026

🎉🚀 We're excited to share our latest insights on #DLBCL www.cell.com/cancer-cell/...! 🧵 How can we understand its clinical & molecular heterogeneity by incorporating the proteome?

Pathogenesis of diffuse large B cell lymphoma proteogenotypes

Enssle et al. perform transcriptomic and proteomic profiling of diffuse large B cell lymphoma (DLBCL), revealing seven proteogenotypes (PGs) that reflect molecular and tumor microenvironment features ...

cell.com

Seminar Alert: *Prof. Elena Conti* 'RNA exosome complex: Molecular Mechanisms of RNA degradation in health and disease' When: 18.06.2026, 14:00 Where: Haus 22-1 (lecture hall H22-1), Neiderad Campus (Uni KliniK), Goethe University RT🙏 @scale-cluster-ffm.bsky.social @goetheuni.bsky.social

Pan-cancer spatial atlas of tertiary lymphoid structures www.science.org/doi/10.1126/... @science.org @utmdanderson.bsky.social

Vince Carey kicking off the 22nd edition of the #CSAMA @bioconductor.bsky.social summer school in Brixen 🇮🇹 #CSAMA2026

✨ Keynote spotlight of #FrankfurtCancerConference 2026: Douglas Hanahan, Distinguished Scholar @ludwigcancer.bsky.social, Lausanne. Renowned for the #HallmarksOfCancer & pioneering work on #tumorigenesis and #TumorMicroenvironment 👉 Register until June 25, 2026! www.frankfurtcancerconference.org

💬 Join us for a CRC Crosstalk Seminar 💬 “Decoding and targeting cellular dynamics in colorectal cancer metastasis” with Dr. Rene Jackstadt (@jackstadt-lab.bsky.social), from HI-STEM gGmbH and @dkfz.bsky.social 📅 Wed, May 20, 2026 🕙 12:00 pm 📍 Lecture Hall, Georg-Speyer-Haus FFM / Hybrid

✨ Keynote spotlight of the #FrankfurtCancerConference 2026: Prof. Carl June, pioneer in CAR T cell therapy and #immunotherapy @upenn.edu. His groundbreaking work led to CTL019, the first FDA-approved CAR T cell therapy in the US. 👉 Register until June 25, 2026! 🔗 www.frankfurtcancerconference.org

For PhD students or postdocs who start out wanting to analyse their own high-throughput data:

Wolfgang Huber@wkhuber.bsky.social · 8mo ago

CSAMA 2026 - Biological Data Science Summer School Bressanone-Brixen, South Tyrol / Italy 24-29 May 2026 csama2026.bioconductor.eu Statistical & computational methods for single cell and spatial omics, with lectures and hands-on exercises in R/Bioconductor.

Online now: Ultra-high-throughput IGH genotyping of 25 global populations reveals population-biased allelic diversity and homozygous V and D gene deletions

Ultra-high-throughput IGH genotyping of 25 global populations reveals population-biased allelic diversity and homozygous V and D gene deletions

The genes that encode our antibodies display extensive variation between individuals. Corcoran et al. developed a high-throughput sequence-based method for identifying variations in antibody genes (ImmuneDiscover). This enabled the sequencing of 2,486 individuals with 25 different population ancestries, identifying variations that are population specific and may underlie differences in disease susceptibility and vaccine response at both an individual and population level.

dlvr.it

📢 Call for Abstracts - Frankfurt Cancer Conference 2026 Present your research September 2-4 as a poster or get selected for a short talk. Share your work, get feedback, and connect at the international #FrankfurtCancerConference. 📆 Deadline: March 26, 2026 🔗 www.frankfurtcancerconference.org

AI agent goes nuts on open source maintainer after having its pull request denied. This is a pretty insane story. Open source development as we've been used to for the last few decades is likely over. 1/ theshamblog.com/an-ai-agent-...

An AI Agent Published a Hit Piece on Me

Summary: An AI agent of unknown ownership autonomously wrote and published a personalized hit piece about me after I rejected its code, attempting to damage my reputation and shame me into acceptin…

theshamblog.com

Save the Date: FRANKFURT CANCER CONFERENCE 2026 Translating Paul Ehrlich’s Magic Bullet into Novel Targeted Therapies 🕗 Wed., September 2, 2026 – Fri., September 4, 2026 📍Campus Westend, @goetheuni.bsky.social, Frankfurt/Main, DE ➡️ www.frankfurtcancerconference.org #frankfurtcancerconference

The Frankfurt Institute for Advanced Studies (FIAS) and the newly funded Cluster of Excellence SCALE are seeking several Independent Research Group Leaders to drive theoretical and computational research in molecular and cellular life science. fias.institute/de/das-fias/...

Great news: The #LOEWE Center Frankfurt Cancer Institute @goetheuni.bsky.social will continue to receive funding from the state of Hesse! 🎉 12 mio € for two more years – a strong signal for the importance of #translational #cancer #research in Frankfurt. Thank you Hesse and everyone involved!!

Im @loewe-fci.bsky.social arbeiten Forschende gemeinsam an translationaler #Krebsforschung. Nun wird das #FCI weiter vom Land Hessen gefördert: Wissenschaftsminister Timon Gremmels hat heute einen Förderbescheid für die Jahre 2026/27 überreicht. 🔗 Mehr: aktuelles.uni-frankfurt.de/allgemein/12...

There are two complementary views of scientific advance: the "heroes" view, individual geniuses driving unique one-of-a-kind advances, and the "multiple discovery" or zeitgeist view, that the time is ripe for a discovery, and the details of who makes it first, where, and how are, well, details.(1/3)

📆 For those who haven't turned the page on their calendar yet, here's a reminder. In November, we look at a colorful piece of microscopy art by Jadranka Macas (Institute of Neurology (Edinger Institute), University Hospital Frankfurt). Read more about it here: 👉 nfdi4bioimage.de/resources-an...

📢 We are announcing the Adaptive Immune Profiling Challenge 2025! Can you predict immune state labels from adaptive immune receptor repertoires? 💰 $10,000 prize pool! 🗓️ Launches Nov 5 on @kaggle.com More Info: uio-bmi.github.io/adaptive_imm...

Our new publication in @cp-immunity.bsky.social: Tertiary lymphoid structures with signs of functional adaptive immune responses in a subset of human gliomas. Association with longer overall patient survival and more immune-permissive tumor microenvironment. doi.org/10.1016/j.im...

Tertiary lymphoid structures in a subset of gliomas that show signs of functional adaptive immune activation and are associated with longer overall patient survival and an immune-permissive tumor microenvironment @cp-immunity.bsky.social www.cell.com/immunity/ful...

Reminder 👇 Interested in improving our R tools for #MassSpectrometry data analysis and integrating them into Galaxy? ⏲️ 3 year position 📍 Bolzano, 🇮🇹 👉 apply if you like: - #rstats SW development - @bioconductor.bsky.social - large-scale #metabolomics data analysis - hiking ⛰️ 🔗 bit.ly/46AMawx

🚀 Postdoc / Bioinformatician in Computational Multi-Omics for Precision Oncology at Heidelberg University Hospital: karriere.klinikum.uni-heidelberg.de/index.php?ac... A great short-term opportunity for anyone looking for a bridge position between PhD, postdoc, or the next career step.

EuroBioC2025 is in full swing here in Barcelona! Day 1 was full of great talks, conversations, and that amazing Bioconductor community energy. Excited for what’s ahead today and tomorrow! #EuroBioC2025 #Bioconductor #OpenScience #Community

Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change. Ie: it's not us (Samtools team)! Be warned

PhD position available in my group in Frankfurt. Explore adaptive immune responses in metastatic colorectal cancer using multi-omics and AIRR profiling. #TRR417 @loewe-fci.bsky.social georg-speyer-haus.de/karriere/ste...

Our paper identifying evidence of off-target probe binding in the 10x Genomics Xenium Breast Gene Panel is now available as a reviewed preprint at #eLife elifesciences.org/reviewed-pre... We look forward to revising the paper to incorporate reviewer recommendations and other updates 🧵👇