I feel honored that my Perspective article with @mayorlab.bsky.social on collective cell migration has been featured in this special collection. Many thanks to the curators, @wumin-lab.bsky.social and Gabriele Stephan, as well as @jcb.org rupress.org/jcb/article/... #CellBio #CellMigration

Journal of Cell Biology@jcb.org · 3w ago

This collection explores emergent phenomena in #CellBiology incl. how cellular events are rapidly coordinated by waves of chemical & electrical signals, how tissue patterning is governed at the cellular level & how cellular interfaces guide cellular migration & morphology rupress.org/jcb/collecti...

Just combed through my old data… et voilà: a tooth of the gill comb. 🐟✨ #FluorescenceFriday #zebrafish #DevBio #SciArt

Hot off the press from the @korostelevlab.bsky.social: Therapeutic approaches for nonsense mutations in CFTR buff.ly/zeUPNLl #RNA #RNATherapeutics @UMassChan.bsky.social

Therapeutic approaches for nonsense mutations in CFTR - PubMed

This manuscript reviews recent developments in suppressing nonsense mutations in the CFTR gene. Nonsense mutations lead to premature termination codons (PTCs)-UAG, UGA, or UAA- that cause the…

buff.ly

1/10 I am truly honored to receive the Hilde Mangold Award from @gfeev.bsky.social! Mangold’s classic transplantation experiments transformed developmental biology and our understanding of self-organization. I am grateful to be associated with this legacy!

🌍 It’s #RareDiseaseDay 2026! 💜 Today we stand with the 300 million people living with a rare disease. Together, we’re showing our colours, raising awareness, and inspiring change by talking about what equity means to us. 👉 Read more: https://go.rarediseaseday.org/NEWS

🎉New paper (co-author) in Reproduction 🎉 We characterize human QRICH2, a sperm-specific, conserved protein essential for normal sperm structure and function, with potential as a non-hormonal male contraceptive target. Check the full article 👉 doi.org/10.1093/repr... #MaleContraception #ReproBio

🔬Join our #ReproductionMS seminar with Dr. @maikbischoff.bsky.social on "Coiling a Duct: How Mesenchymal Cells Sculpt Male Reproductive Organ Architecture" this Wednesday, 11 February 12pm CET. DM for Zoom details.

🧬 𝗡𝗲𝘄 𝘆𝗲𝗮𝗿, 𝗻𝗲𝘄 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗵𝗼𝗿𝗶𝘇𝗼𝗻𝘀! 🧠❤️ Two new research groups have joined our institute – and we’re excited to welcome them! 𝗣𝗦: 𝗞𝗮𝗿𝗶𝗻 𝗶𝘀 𝗵𝗶𝗿𝗶𝗻𝗴! Take a look at her job openings here: lnkd.in/gGQimf8

PhD position available 🔬📝 🔥last day to submit your application! stellen.uni-muenster.de/jobposting/d...

Maik Bischoff@maikbischoff.bsky.social · 7mo ago

Join us to study developmental cell biology with a focus on cell migration and morphogenesis. More info about our research: www.bischofflab.com Job posting and application details: focalplane.biologists.com/cell-biology... #Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila

New biosensor💥 🎯precisely measures endogenous UBE3A activity with super high sensitivity 📌providing a powerful tool for studying Angelman syndrome & advancing therapeutic development for UBE3A-related disorders link to study: www.sciencedirect.com/science/arti...

A luminescence-based biosensor to measure endogenous UBE3A activity

Loss- and gain-of-function (LOF and GOF) mutations in the E3 ubiquitin ligase UBE3A cause distinct neurodevelopmental disorders. The AZUL domain of UB…

sciencedirect.com

Excited to share @rbrianroome.bsky.social ‘s beautiful paper on development of the dorsal horn of the mouse spinal cord @science.org This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down. www.science.org/doi/10.1126/...

Ontogeny of the spinal cord dorsal horn

The dorsal horn of the mammalian spinal cord is organized into laminae where each layer is populated by different neuron types, has distinctive circuit connections, and plays specialized roles in beha...

science.org

I am happy our recent study on the human sperm head-tail junction is now online. We find that SUN5 form an hexagonal lattice at the nuclear membrane, rationalising how mutations in SUN5 lead to infertility. Great work of @cryonas.bsky.social ! www.biorxiv.org/content/10.1...

SUN5 forms a regular protein lattice reinforcing the sperm head-tail junction

Linker of nucleo- and cytoskeleton (LINC) complexes reside in the nuclear envelope, the double-membrane surrounding the nucleus, where they establish a physical bridge between nucleus and cytoplasm. L...

biorxiv.org

There is still over a week left to apply. Please send your documents to maik.bischoff@uni-muenster.de

Maik Bischoff@maikbischoff.bsky.social · 7mo ago

Join us to study developmental cell biology with a focus on cell migration and morphogenesis. More info about our research: www.bischofflab.com Job posting and application details: focalplane.biologists.com/cell-biology... #Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila

#eNeuro: Ringelberg et al. identify a key role for excitatory neuron loss of UBE3A in motor, innate, and sleep behavioral phenotypes of Angelman syndrome model mice. https://doi.org/10.1523/ENEURO.0453-24.2025

Hong Cheng and collaborators show how alternative polyadenylation can facilitate muscle differentiation and regeneration: 3’UTR shortening of differentiation-gene mRNAs alleviates their repression by myomiR muscle-specific miRNAs link.springer.com/article/10.1...

3′UTR shortening alleviates miRNA repression of mRNAs critical for muscle stem cell differentiation - The EMBO Journal

Alternative polyadenylation (APA) modulates gene expression by altering 3′ untranslated region (3′UTR) length. Although 3′UTR lengthening typically accompanies cell differentiation, we unexpectedly ob...

link.springer.com

New paper out 🔥! Small promoter, big potential🧬 We show that the ultra-compact Calm1 promoter efficiently targets human neurons in brain organoids and is a promising alternative to hSyn for AAV gene delivery. Huge thanks to everyone who contributed to this work! 🧠 📄: www.nature.com/articles/s41...

Compact Calm1 promoter enables AAV mediated neuron-targeted expression in human iPSC-derived brain organoids - Scientific Reports

Scientific Reports - Compact Calm1 promoter enables AAV mediated neuron-targeted expression in human iPSC-derived brain organoids

nature.com

1/2 A special #FluorescenceFriday for me! 🌈 Live muscle precursors on a pupal fly testis (Lifeact-eGFP, 🔥-depth-coded). It's special because this is on the poster for the @sfb1348.bsky.social Meeting in May — my first time being featured as a speaker on a poster! 😀 Feeling very grateful & excited!

So excited to share this as a new junior PI: My brand-new lab website! 🎉🪰🌀 www.bischofflab.com Please pass it on to young, motivated researchers looking for PhD positions 😊 And for the #FluorescenceFriday community: don’t miss the SciArt Gallery! #CellBio #DevBio #PhDjob #PhDposition #Science

Amazing paper with gorgeous imaging 🔥 from @mathpreu.bsky.social journals.biologists.com/dev/article/...

A developmental atlas of zebrafish gills links early vascular patterning to adult architecture

Summary: An atlas of zebrafish gill vasculature reveals developmental asymmetries and shows how early vascular patterning shapes filaments and lamellae and is reflected in adult gill architecture.

journals.biologists.com

Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉 Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life 🔗 journals.biologists.com/dev/issue/15... #FluorescenceFriday #LifelongDevSI

A developmental atlas of zebrafish gills links early vascular patterning to adult architecture Read this #LifelongDevSI #OA Research Article by Mathieu Preußner @mathpreu.bsky.social, Virginie Lecaudey @vlecaudey.bsky.social and colleagues: journals.biologists.com/dev/article/...

My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing 🔵 lifeact & 🔴 RFP-nls Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨ 🔗 www.nikonsmallworld.com/galleries/20... #NikonSmallWorld #Microscopy #ScienceArt

1/12 A very special moment for me! 🎉 My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes. rupress.org/jcb/article/... #cellbio #devbio #science 🧵for details

New perspective by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/... #CellBio #CellMigration #Morphogenesis #Development #Science

We’re excited to announce the launch of our new website at angelman.org! 🎉 Our updated site features easy navigation and filters that help you find the resources, clinics, research, and support you need on any device. Check it out!➡️ angelman.org

A Boa Constrictor brain-derived cell expressing a viral glycoprotein (magenta) and stained for actin (yellow) and DNA (white). #FluorescenceFriday

FINALLY out in #Science Advances! 🎉 3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author! It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀 www.science.org/doi/10.1126/... #DevBio #CellBio #Microscopy

For #fluorescencefriday the Mesoscopic Integrated NeuroImaging Data (MIND) platform @westernu.bsky.social presents abeta plaques and blood vessels in the 🧠 of our ApoE4 mouse model of AD. 🧪 #clearing #lightsheet 🔬 Courtesy of Arash Salahinejad, Luke Smolders and @shahrzadbahrampour.bsky.social

Stunning images!

Mathieu Preußner@mathpreu.bsky.social · last yr.

1) Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood. #zebrafish #gills #microscopy

1) Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood. #zebrafish #gills #microscopy