Honored to be part of the 2026 Leading Edge Fellows Zara Weinberg Cohort! Thanks to all my mentors and collaborators for their support. Looking forward to being part of this amazing community of scientists!

Leading Edge Fellows Program@leadingedgeprogram.bsky.social · 2mo ago

We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/

Fun news! @gcbias.bsky.social and I are teaching a 2-week online population genetics workshop this summer to raise money for the Center for Population Biology at UC Davis. We're trying to gauge interest -- please fill this out if you might be interested! And please share broadly!

Davis Summer Population Genomics Program

Want to learn population genetics? Please fill out this form to indicate your potential interest in a 2-week intensive online summer population genetics course taught by Jeffrey Ross-Ibarra and Graham...

docs.google.com

Last paper of my PhD is out! This started as a curiosity driven project in the last 6 months of my Ph: how circadian clocks organize across the organism? 2022 kicks in and thanks to the fly cell atlas we could start answering it! Thanks to all our collaborators and to the amazing fly community.

Sebastian Kadener@skadener.bsky.social · 7mo ago

Our new paper is out on bioRxiv and we’re really excited about it! www.biorxiv.org/content/10.6... We show that circadian clocks in the fly brain are far more distributed than the classic view. Huge kudos to the authors, especially @inespatop.bsky.social and Anne, and to our collaborators!!

🚨🚨🚨 Please RT! We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets. Deadline: 30/09/25👇

This is so cool!

Genes & Development@genesdev.bsky.social · last yr.

📽️ G&D Tapes 📽️ G&D author, Noah Helton tells us about their new study in #genesdev, revealing an intriguing link between stress granule formation and the integrated stress response. #OpenAccess @smslmoon.bsky.social Read the full story here: ➡️ tinyurl.com/gd352899

Hey #Drosophila folks ! #FlyCROSS is back and #Mentor surveys are open NOW ! If you're a faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - we'd be delighted to have you as mentors to empower early career scientists in the #Dros community !

Summer 2025 Survey For Mentors : FlyCROSS Mentor Mentee Matching Program

We appreciate you taking the time and volunteering to be a mentor! Add dmelcross@gmail.com to your email address book or safe sender list, so that you can receive our emails. To be a participating me...

docs.google.com

Very excited to share our new paper out now in @MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...

U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation

Kim et al. uncover a role for U1 snRNP in regulating internal promoter activity. Beyond its canonical role in splicing, U1 snRNP suppresses premature polyadenylation, enabling upstream transcription t...

cell.com

The timeline of co-transcriptional #mRNA processing and #modification may have to be revised: cleavage, termination, and #m6A deposition may occur earlier than most #splicing! Potential textbook changing study in bioRxiv by edueyras.bsky.social & Rippei Hayashi labs! www.biorxiv.org/content/10.1...

Single-molecule multimodal timing of in vivo mRNA synthesis

mRNA synthesis requires extensive pre-mRNA maturation, the organisation of which remains unclear. Here, we directly sequence pre-mRNA without metabolic labelling or amplification to resolve transcript...

biorxiv.org

This sounds really really fun and useful.

Beth Cimini 🔬💻📊@bethcimini.bsky.social · last yr.

BIG NEWS - for the first time ever, we're running a Bioimage Analysis Beginnings Bootcamp. Learn #bioimageanalysis from awesome folks, and gain familiarity with some new tools as well as how to pick the right tool in the first place. Aug 4th-8th - apply here (soon!) forms.gle/d2fCXsrWHVP8...

This is SO useful for the community. Models for PD, SD, and more at the end of a click. Thanks Jax and all the people that made this possible!

Mark Cookson@markrcookson.bsky.social · 2y ago

May as well start out with our big resource. We spent a long time getting this up and running - and it's now a real thing and still growing! Repost!!! www.jax.org/jax-mice-and...

Why can a human tolerate a drug that globally inhibits transcription? Why do transcription inhibitors not cure cancer? Our first paper of 2025 may help explain (some) of this! So incredibly proud of @tobiaswilliams.bsky.social & Ewa Michalak who led the work! www.cell.com/molecular-ce...

mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription

Transcription inhibitors also disrupt nuclear export. Here, Williams et al. reveal that mRNA export factors sense transcription inhibition and adapt by storing mature export-competent mRNA in nuclear speckles. This enables rapid release when transcription resumes and ensures retention of cellular identity and viability during a transient global transcription insult.

cell.com

I can’t be more proud of our team of amazing scientists. We had a great conference with science talks, career panels, and networking sessions! We got RAs, students, postdocs, Pis, and scientists working in academia, industry, and policy. I am inspired, proud, and energized (and also tired ;)

Latinx Scholars at Harvard Medical School@latinxscholarshms.bsky.social · last yr.

Today we hosted the first New England LatinX Conference! We thank the science and panel speakers, all the 150 participants, our co-organizers (@giosg.bsky.social and the NEx scientists, and the Harvard GSAS LatinX students), and sponsors (New England Biolabs, Guilliam Fellows Program, and Beantown)

And on other news. My first contribution to science as a postdoc with @stirlingchurchman.bsky.social is out! We discuss the knowns and unknowns of post-transcriptional splicing. It was really fun to write with the great @karinechoquet

Nature Reviews Genetics@natrevgenet.nature.com · last yr.

New online! The regulation and function of post-transcriptional RNA splicing

It’s so nice to see this work finally out! It developed so much since its early days. The idea of long lived RNA as experience decoys is huge. Still a lot of work to be done but this is a great first step forward. Happy to have been part of it!

Sebastian Kadener@skadener.bsky.social · last yr.

Super excited our paper on circRNA stability in the brain and their use as life experience markers is out! @inespatop.bsky.social www.cell.com/cell-reports...

@evapillai.bsky.social and I had fun writing a brief comment www.science.org/doi/10.1126/... (originally featuring an enlightening comparison to a soufflé au fromage that unfortunately disappeared from the final version per Science house style)

Archaea go multicellular under pressure

A microbe from the Dead Sea switches to a tissue-like form when compressed

science.org

💫 New preprint from the lab: Comparing great ape cerebral organoids, we found that human-specific morphoregulatory signatures in basal radial glia characterise neocortex evolution. Fantastic work from super-talented PhD student Theresa Schütze! www.biorxiv.org/content/10.1...

So so cool

Nature Biotechnology@natbiotech.nature.com · last yr.

A method to generate large mitochondrial DNA deletions in human cells enables the study of their pathogenicity, which could inform future treatment strategies. www.cell.com/cell/fulltex... #NBTHighlight

Metascience and AI Postdoctoral Fellowships Grants of up to $250,000 (USD) over up to two years will be awarded to social sciences and humanities postdoctoral researchers who study the implication of AI for Science. Deadline: April 10, 2025 @sloanfoundation.bsky.social 🧪 sloan.org/programs/dig...

Call for submissions: Metascience and AI postdoctoral fellowship | Alfred P. Sloan Foundation

Our mission is to make the world a better place through the advancement of scientific knowledge.

sloan.org

Excited to share the work of Jonathan Perr where he uncovered a surprisingly common feature of cell surfaces - the presentation and clustering of RNA binding proteins with #glycoRNA. Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...

RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry

Mammalian cells present RNA-binding proteins on the cell surface that form clustered domains containing glycoRNAs.

cell.com

RNA xkcd.com/3056

HHMI Science Department is hiring! We are looking for an outstanding immunologist/ cancer biologist to join our senior leadership team. Remote work eligible, 24 weeks a year onsite, possibility of running a small lab with HHMI support @hhmi.bsky.social hhmi.wd1.myworkdayjobs.com/External/job...

Senior Director - Scientific Officer

Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all. As a biom...

hhmi.wd1.myworkdayjobs.com

Valérie Hilgers and co-workers @hilgerslab.bsky.social @mpi-ie.bsky.social and @zmbh.uni-heidelberg.de show that the conserved #neuronal #protein Pumilio differentially binds to mRNA 3′ UTR isoforms to regulate localization of synaptic proteins. #neuroscience www.embopress.org/doi/full/10....

It's @scipyconf.bsky.social submission time again! This year I am running the Bioinf/Comp Bio/Neuroscience track, covering how Python is advancing science and problem-solving in those fields. Let me know if y'all have questions, and looking forward to the submissions!

😊🔬 Happy to share our preprint manuscript from my PhD! This study sheds light on stimuli specific activity-dependent gene expression and its changes during neuronal development in vitro. Looking forward to discussions and new perspectives!

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Neuronal development shapes activity-dependent gene expression in a stimulus-specific manner https://www.biorxiv.org/content/10.1101/2025.02.19.638694v1

Cool science with great people. Recommend!

Lucas Farnung@lucas.farnunglab.com · 2y ago

If you like our visual biochemistry approach at the intersection of transcription and chromatin, consider applying to our lab as a post-doctoral researcher. More info here: farnunglab.com We are also always looking for Masters students to conduct their thesis research in the Farnung Lab.

Latin America and open access

Sar Crespi@boron110.bsky.social · 2y ago

This week on the @science.org Podcast: Latin America is a leader in nonprofit open-access journals. But it struggles to give them global visibility w/ @sofiamoutinho.bsky.social www.science.org/content/podc...

#paperalert! In our new study, we ask the question: Can we predict RNA stability across conditions and protocols, based solely on experimental and/or computationally predicted RNA binding protein target sites? Read the paper to find out ! www.biorxiv.org/content/10.1...

Cell-type specific prediction of RNA stability from RNA-protein interactions

RNA-binding proteins (RBPs) are important contributors to post-transcriptional regulatory processes. The combinatorial action of expressed RBPs and non-coding factors bound to the same transcript dete...

biorxiv.org

Big thanks to @odedrechavi.bsky.social and @ethanewe.bsky.social for the Dispatch in @currentbiology.bsky.social on our amyloid inheritance paper. www.cell.com/current-biol...

Inheritance: Leaving sticky notes for the children

It is currently unknown to what degree parents’ life history can affect the next generation and how such information might be transmitted. A new study finds that nematodes transmit amyloid proteins to...

cell.com

🚀 New Event Alert! 🚀 Join us for an exciting session with Yanina Bellini Saibene (@yabellini) on using GitHub Copilot with R! Don’t miss this hands-on demo & insightful talk! 👉 RSVP: www.meetup.com/rladies-rome... #AI #GitHubCopilot #RStats #DataScience #WomenInTech @fgazzelloni.bsky.social

Using GitHub Copilot (and others LLM) with R, Tue, Dec 10, 2024, 7:00 PM | Meetup

Join us for an exciting and insightful session with **Yanina Bellini Saibene**, as she explores the integration of **GitHub Copilot** (and other **Large Language Models**,

meetup.com

🧪 🍎 📍 🌊 🦑 pathwaystoscience.org Paid Summer 2025 Undergraduate Research Placements; financial support in graduate school; tips on applications and other resources; opportunities in ocean sciences and engineering