"flexible, data-adaptive algorithms did not outperform classical parsimonious regression models for covariate adjustment in RCTs" www.sciencedirect.com/science/arti...

How should covariates be handled in randomized trials? Empirical evidence from 50 trials and recommendations for practice

Covariate adjustment can improve precision and power in randomized clinical trials and is recommended by major regulatory agencies. However, there is …

sciencedirect.com

Interesting single case series investigating use of Tetris to reduce anxious flashword imagery amongst young people - nice to see extensions of this work to intrusive images beyond trauma. link.springer.com/article/10.1...

Developing a Game-Based, Single-Session Intervention for Youth Anxiety: Early Translational Findings Targeting “Flashforwards” - Cognitive Therapy and Research

Background Anxiety disorders are the most prevalent form of psychopathology and place a high burden on youth transitioning into adulthood. Scalable, effective, and appealing early interventions are ur...

link.springer.com

📝 New preprint: Causal effects of routine CBT on interpersonal problems (N = 687) We provide an estimate of the average treatment effect and test for potential heterogeneity of treatment effects. doi.org/10.31234/osf... Short 🧵 (1/5)

PsyArXivBot@psyarxivbot.bsky.social · 5mo ago

Beyond Symptom Reduction: The Causal Effect of Cognitive Behavioral Therapy on Interpersonal Problems: https://osf.io/xg9qn

Is the link btwn Adolescent SSRI use & Bipolar Disorder causal? Our study suggests: 𝐍𝐨. When accounting for unmeasured confounding (e.g., depression severity) via Instrumental Variable analysis, the evidence for a causal link disappears. mentalhealth.bmj.com/content/28/1... #Psychiatry #MedSky

Antidepressant treatment and risk of subsequent bipolar disorder in adolescents with unipolar depression

Background Selective serotonin reuptake inhibitors (SSRIs) are a common treatment for depression and anxiety in adolescents but are associated with an increased incidence of bipolar disorder (BD). Whe...

mentalhealth.bmj.com

Large, well-conducted (at first glance) RCT finding no difference between 1.5 g of ω-3 fatty acids vs placebo in children and adolescents with moderate to severe pediatric major depressive disorder. jamanetwork.com/journals/jam...

ω-3 Fatty Acids in Pediatric Major Depressive Disorder

This randomized clinical trial assesses the efficacy of ω-3 fatty acids in reducing depressive symptoms and improving quality of life in children and adolescents with moderate to severe major depressi...

jamanetwork.com

New study (n=6,125) finds that starting trauma-focused psychotherapy for PTSD while using psychotropic medication is linked to reduced therapeutic gains. The strongest negative associations appeared for antidepressants. doi.org/10.1159/0005...

"the first fully powered trial to assess the efficacy and safety of an immersive virtual avatar-based intervention [...] Challenge-VRT was significantly more effective than enhanced treatment-as-usual in reducing the severity of auditory hallucinations" New Article www.thelancet.com/journals/lan...

Immersive virtual reality-assisted therapy targeting persistent auditory verbal hallucinations in patients diagnosed with schizophrenia spectrum disorders in Denmark: the Challenge assessor-masked, ra...

Challenge-VRT showed short-term efficacy in reducing the severity of auditory verbal hallucinations in patients with schizophrenia, and the findings support further development and evaluation of immer...

thelancet.com

What’s the most effective way to deliver exposure therapy for anxiety? We tested: 🔹 Behavioural experiments (BE) 🔹 Cognitive restructuring before exposure 🔹 Habituation-based approaches BE had the best outcomes. 🧠 How do you implement exposure? 🔗 bit.ly/3YTlR0n #mentalhealth #ClinPsy

Thanks to everybody who chimed in! I arrived at the conclusion that (1) there's a lot of interesting stuff about interactions and (2) the figure I was looking for does not exist. So, I made it myself! Here's a simple illustration of how to control for confounding in interactions:>

Julia M. Rohrer@dingdingpeng.the100.ci · last yr.

Does anybody have a good visualization to explain how interactions can be confounded, and why interactions require interaction controls? @urisohn.bsky.social maybe? (Asking because I have an idea, but want to check out what exists already before investing the effort)

"The most important aims of psychotherapy: to love, to work, and to find meaning" Even if the final naming of the clusters can be questioned, it is nevertheless an interesting approach to work out the underlying aims of the different schools of psychotherapy. www.thelancet.com/journals/lan...

The most important aims of psychotherapy: to love, to work, and to find meaning

In the January issue of The Lancet Psychiatry, Michaela Ladmanová and colleagues1 published a qualitative meta-analysis on client-reported psychotherapy outcomes. Their analysis revealed nine clusters...

thelancet.com

tCBT New Paper: Using metaphor to facilitate cognitive detachment in cognitive behaviour therapies Full free text at www.cambridge.org/core/journal...

Preprint updated: Evidence that Tetris Reduces Immediate but Not Subsequent Daily Intrusions of a Trauma Film: A Multilab Replication Study osf.io/preprints/ps...

1. There is hardly any evidence on what happens after the end of depression treatments. Finally, Voderholzer et al. published their review on 19 such studies comparing antdepressant tx and psychotherapie or their combination. doi.org/10.3389/fpsy...

Frontiers | Enduring effects of psychotherapy, antidepressants and their combination for depression: a systematic review and meta-analysis

doi.org

Depression is preventable. Our individual participant data meta-analysis based on >7000 participants proved that psychological interventions reduce the incidence of depression within a year from 10% to 6%. authors.elsevier.com/sd/article/S...

Question for #WorldSnakeDay: Is this a female adder? Could it be pregnant? 🐍 #herps #snakes

Learning during sleep in humans: A comprehensive overview of the history of sleep learning research, from its empirical beginnings in the 1940s to the present day.  www.sciencedirect.com/science/arti...

"There’s good news for the ice sheet, which may withstand temporary breaches in 1.5C, but emissions must still drop quickly" - latest Nature study with PIK scientist Niklas Boers covered by Euronews. www.euronews.com/green/2023/1...

Scientists say there’s still time to stop Greenland ice sheet melting

There’s good news for the ice sheet, which may withstand temporary breaches in 1.5C, but emissions must still drop quickly.

euronews.com

Lack of contextualization affects cognitive testing, but the problem is even broader. For example, one of the most common stress inductions prompted one of our puzzled Kenyan participants to remark: "Why are we being interviewed for a job by butchers?" www.psychologicalscience.org/observer/gs-...

Ed Hagen@edhagen.net · 3y ago

An example of cultural bias in cognitive tests. This item has been used to evaluate South African children. 🧪 Source: Assessing the Culture Fairness of an Intelligence Test by Adjusting the Test Times and Pictorial Examples www.proquest.com/docview/2524...

Which brings my to the best paper I've read this year, by @samzhang.bsky.social, @aaronclauset.bsky.social and colleagues.