Peer review as it should be. From an ASM journal. Fine maybe the decision makes you go “ugh” but brilliantly inciteful and constructive review comments that undoubtedly make the paper better.
Jose Bengoechea
@josebengoechea.bsky.social
Working on innate immunity & host-pathogen interactions. Finding new ways to treat infections by antibiotic resistant bacteria. All views are my own.
Delighted to share our last Kleb work. From developing a platform to asses in real time bugs effect on vessels to nail down the role of the T6SS and the CPS including in vvo work. Superb collaboration and hard work of PhD student @safimicro.bsky.social
Nature Microbiology@natmicrobiol.nature.com · 3w agoOut Now! Klebsiella pneumoniae inhibits vasodilation through capsule and T6SS-dependent pathways #MicroSky
Delighted with the publication in @cp-trendsmicrobiol.bsky.social of a concept note where we propose a new framework to capture the complexity of infections in vivo: metapopulation infection biology. Supported by Klebsiella and Cryptococcus research among other pathogens www.cell.com/trends/micro...
Beyond intracellular–extracellular divide toward metapopulation infection biology
The binary classification of pathogens as intracellular or extracellular fails to capture the complexity of infections in vivo. We propose the metapopulation infection biology framework, in which infe...
cell.com
Meet the ‘princess’ mosquito 👑 🦟 LSHTM establishes UK’s first laboratory colony of Aedes vexans, a mosquito that's very 'high maintenance' Find out how this pioneering research is helping to protect the UK from disease threats as our climate changes 👉 www.lshtm.ac.uk/newsevents/n...
Recruiting a postdoc to join my lab at @lshtm.bsky.social to work in an MRC porgramme grant funded project to dissect the gut colonziation by Klebsiella. In vivo and in vitro models, and new approaches to identify Klebsiella factors involved. jobs.lshtm.ac.uk/vacancy.aspx...
Job Opportunity at LSHTM: Research Fellow
The London School of Hygiene & Tropical Medicine (LSHTM) is one of the world’s leading public health universities. Our mission is to improve health and health equity in the UK and worldwide; working i...
jobs.lshtm.ac.uk
We asked the Editor-in-Chief of Microbiology Horizons, Tania Dottorini, what our new and exciting multidisciplinary journal can offer the community. To join Tania's passion and excitement for Microbiology Horizons, follow the link to find out more: https://microb.io/4ttwnbm
📝 LSHTM & @ukhsa.bsky.social have renewed & expanded #UKPHRST academic partnership. 🤝LSHTM will lead a consortium from UK & 6 countries across Africa & SE Asia to co-produce research to protect global health security. Funding: DHSC with UK ODA & NIHR 👉 www.lshtm.ac.uk/newsevents/n...
LSHTM to lead research partnership in £18m outbreak response initiative | LSHTM
The London School of Hygiene & Tropical Medicine (LSHTM) has been selected to lead the research arm of the UK Public Health Rapid Support Team (UK-PHRST) in an £18m initiative to continue to help
lshtm.ac.uk
The T6SS is a widespread nanoweapon deployed by #bacteria, but why is it deployed heterogeneously? @cascaleslab.bsky.social &co show that #Ecoli adopt distinct #T6SS attacker "ON" & defender "OFF" roles to optimize survival, a key strategy in microbial warfare @plosbiology.org 🧪 plos.io/3S5dL45
Want to learn more about LSHTM's #MRes in Infectious & Tropical Diseases? 😃 Join our online information webinar on Thursday 28 May 2026 (14:00-15:00 UK time) to learn more about our exciting new programme. Book your place 👉 lshtm.zoom.us/webinar/regi... #PublicHealth
So we blocked IFNγ in Mtb infected macaques and….the animals were fine. Turns out mice overestimate the importance of IFNγ in TB because IFNγ drives iNOS in mice but not macaques or humans. This means we don’t actually know how T cells suppress Mtb. rdcu.be/ff9GB #tuberculosis #immunology
IFNγ blockade in Mycobacterium tuberculosis infected macaques alters the granuloma environment but not bacterial control
Nature Communications - Here, the authors show that IFNγ blockade does not impair resistance to Mycobacterium tuberculosis infection in macaques, opposed to what has been observed in mice, due...
rdcu.be
Come join us! 4 year PhD position in infection biology/microbiology available associated to our newly funded Clinical Academic Group “Patient-tailored management of bacterial infections in the age of antimicrobial resistance”. Applications via: www.jobbnorge.no/en/available.... @cansuit.bsky.social
PhD fellow in infection biology/microbiology (297648) | UiT The Arctic University of Norway
Job title: PhD fellow in infection biology/microbiology (297648), Employer: UiT The Arctic University of Norway, Deadline: Tuesday, April 28, 2026
jobbnorge.no
LSHTM: where your 'what ifs' become your reason why... This #WorldHealthDay find out how you could become part of our community, tackling the complex challenges of global & #PublicHeath with clarity, compassion and conviction. Join us: explore our programmes: www.lshtm.ac.uk/study?utm_so...
Latest from the lab! Between clinical S. aureus, most gene transfer mechanisms are blocked, yet lateral transduction remains highly efficient. Restriction modification-defective strains act as gateways for horizontal gene transfer, enabling DNA flow across populations. rdcu.be/fbNQK
Immune-deficient bacteria serve as gateways to genetic exchange and microbial evolution
Nature Communications - The efficiency of horizontal gene transfer between different bacterial lineages is often unclear. Here, Figueroa et al. show that lateral transduction is the primary driver...
rdcu.be
We've been we've been working on this for quite a while now (hopefully published soon). Grateful to @proftracypalmer.bsky.social for concinving me & @lislowe.bsky.social that mycobacteria produce inter-bacterial toxins. Team science, led by @sambenedict5.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
Introducing the #MRes in Infectious & Tropical Diseases LSHTM’s exciting new #postgraduate degree putting you at the heart of our world-leading research: → Learn from the experts → Build your network → Study in a unique environment Applications now open 👉 www.lshtm.ac.uk/study/course...
@lshtm.bsky.social launches its new MRes in Infectious & Tropical Diseases, a research-focused Master’s. It is based within LSHTM’s Faculty of Infectious & Tropical Disease. Strong option for intercaled students. More details here: www.lshtm.ac.uk/study/course...
MRes Infectious & Tropical Diseases | LSHTM
lshtm.ac.uk
BREAKING NEWS: Deadly outbreak of #meningitis B in UK LSHTM experts discuss latest situation, including access to #MenB #vaccines More: www.lshtm.ac.uk/newsevents/n... #PublicHealth
👋We welcomed Director-General of @who.int & LSHTM alumnus @drtedros.who.int who returned to LSHTM this week to discuss how we can strengthen collaborations to tackle major #GlobalHealth challenges.🌍 👉 www.lshtm.ac.uk/research/cen...
Great @imibirmingham.bsky.social seminar by the brilliant @josebengoechea.bsky.social who has uncovered another cool and important mechanisms in Klebsiella pneumoniae virulence (no spoilers because unpublished data)
🔬 New work from the Mazel Lab engineers programmable conjugative plasmids to selectively target MDR bacteria and the resistance plasmid pOXA-48, blocking its spread in complex communities. ✍️ @amazeld.bsky.social & coll. @pasteur.fr 📖 shorturl.at/GZdJu #MicroSky #AntibioticResistance #Conjugation
I am rather worried that this government not only will actively fail UK universities but also screw over one of the gems of UK economy - science and life science, particularly. Will UKRI's funding buckets shore up UK research? share.google/B92vQ7E6nEOK...
Will UKRI’s funding buckets shore up UK research’s sandcastle?
Academics’ concerns are mounting as news drips out of the research councils about cuts and freezes ahead of a major funding restructuring intended to promote interdisciplinarity and transparency. But ...
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👋LSHTM offers #scholarships to tackle barriers to education for students from all backgrounds. Check out our First and Next Generation Scholarships for home fee students & those interested in distance learning MSc programmes. Apply by 27 March 2026👉 www.lshtm.ac.uk/study/fees-a...
Join us this Thursday for our online seminar series, Safe Microbiome Perturbations. Featuring a live discussion on 'Gut Microbiome and Probiotics.' Register now: https://microb.io/3OBhVPs #GutMicrobiome #WebinarSeries
Insights into how #Staph aureus adapts to the bovine host by unlocking nutrients from the dairy niche. Great work by Amy Pickering, Jamie Gorzynski and others in the group. Bacterial metabolic remodeling by convergent evolution after a host switch.|Science Advances www.science.org/doi/10.1126/...
Bacterial metabolic remodeling by convergent evolution unlocks nutrient availability after a host switch
Staphylococcus aureus has undergone metabolic remodeling to adapt to the dairy niche.
science.org
On this plus side, the number of billionaires in the UK rose from 15 in 1990 to 165 in 2024. Huzzah!
Craig Winstanley@cwinstan.bsky.social · 6mo agoSo to summarise… BBC globally admired, we trash it Universities & scientific research punching well above our weight, we are trashing it NHS rated best healthcare system as recently as 2017, we are trashing it Creative industries - getting trashed Still, mustn’t grumble
#WeekendRead #MicrobiotaPower! Tsai, @diehllab.bsky.social &co show @ Science Immunology that E. coli flagellin is recognized by TLR5 on intestinal epithelial stem cells to recruit gut protective CCR2+ monocyte-derived macrophages, decreasing colitis! #IBDs doi.org/10.1126/sciimmunol.adr4057
Intestinal epithelial TLR5 signaling promotes barrier-supportive macrophages
Colonic stem cell TLR5 sensing of microbes promotes macrophage recruitment and maturation to support intestinal barrier repair.
doi.org
Milestone of the lab...10000 strains in our collection!
#Klebsiella infections are a serious & growing #PublicHealth threat For #AntimicrobialAwarenessWeek, @josebengoechea.bsky.social discusses the dangers of bacterial infections, antimicrobial resistance & the global efforts to tackle it. @lshtmamrcentre.bsky.social www.lshtm.ac.uk/newsevents/e...
For anyone interested in doing a PhD at the interface of microbiology and immunology focusing on how AMR pathogens subvert host defenses...you may consider applying to our MRC LID DTP project in which we will explore how Klebsiella hijacks the immune checkpoint PD-L1 mrc-lid.lshtm.ac.uk/apply/
How to Apply - MRC London Intercollegiate Doctoral Training Partnership Studentships
MRC LID is open for application for 2026-27 PRE-APPLICATION STEPS 1. Find out more about...
mrc-lid.lshtm.ac.uk