Kitty Murphy

@kittybmurphy.bsky.social

Postdoc at Globe Institute, University of Copenhagen 🇩🇰 she/her Interested in the phenotypic effects of archaic DNA present in modern human genomes 🧬

Join us! Research Fellow role at UCL @ukdri.ac.uk @uclqsion.bsky.social with me & @sj-marzi.bsky.social studying oligodendrocytes, genetics & epigenetics in ageing & neurodegeneration using multiomics/bioinformatics. Collaboration with Alexi Nott & @rikeshrajani.bsky.social Closing date: 2nd June

Dementia Researcher@dementiaresearcher.bsky.social · 3mo ago

Research Fellow role at UCL @ukdri.ac.uk with @dervissalih1.bsky.social studying oligodendrocytes, genetics and epigenetics in ageing and neurodegeneration using multiomics and bioinformatics. Closing date: 2nd June www.dementiaresearcher.nihr.ac.uk/job/research...

Computational biologists, sign up! 👩‍💻🧑‍💻 Don’t miss out on the chance to share your work and exchange ideas. Abstract deadline: 12th August See you there 🤓

@londonomics.bsky.social · last yr.

Are you an Early Career Researcher in bioinformatics? Then this symposium is for you 💡 Join us for a day of talks, networking and career discussions. Present your work to get fresh new ideas and the chance to win prizes 💸 Featuring @avsecz.bsky.social of Google DeepMind as our keynote speaker⚡️

Londonomics is back with its second workshop of the year: computer science for bioinformaticians 💡 4 pm @ UCL, with a pizza and drinks social after for an opportunity to network with fellow computational ECRs dotted around London ⚡️

@londonomics.bsky.social · last yr.

Join us today for a workshop on computer science for Bioinformaticians! 🧑‍💻👩‍💻👨‍💻 More info and tickets (only a few left!) here: www.eventbrite.com/e/londonomic...

Excited to share that a chapter of my PhD has just been published in Nature Communications! We profiled the transcriptomic and chromatin landscapes of microglia expressing the different APOE variants, which were xenografted into the brains of an Alzheimer's disease (AD) mouse model 🧠🧬 1/n

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Excited to see a part of my PhD work out in the 🌍 We developed CHAS using 🧠 acetylation profiles, but it can be extended! Would love to hear from you if you try it with other tissues and cell types 🫁 🩸🫀 Lucky to have worked on this with an excellent team, more details below 👇🏻

Sarah Marzi@sj-marzi.bsky.social · last yr.

We are so happy to share our latest paper "CHAS infers cell type-specific signatures in bulk brain acetylation studies of neurological and psychiatric disorders". www.cell.com/cell-reports... @ukdri.ac.uk @kingsioppn.bsky.social @imperialbrains.bsky.social

Londonomics is back! ⚡️ Join us next Thursday 4pm @ The Francis Crick Institute. Don’t sleep on this - only one ticket left!

@londonomics.bsky.social · last yr.

We’re excited to bring you a series of talks and workshops 💥 Kicking things off with all things single-cell analysis with Dr @kristinaulicna.bsky.social 👩‍💻 🧬 More info and FREE tickets (only 1 left!) here: www.eventbrite.com/e/londonomic... Talk followed by a networking social 🍕

We’re excited to bring you a series of talks and workshops 💥 Kicking things off with all things single-cell analysis with Dr @kristinaulicna.bsky.social 👩‍💻 🧬 More info and FREE tickets (only 1 left!) here: www.eventbrite.com/e/londonomic... Talk followed by a networking social 🍕

Londonomics presents: Single-cell analysis with Dr Kristina Ulicna

The first of a series of Londonomics workshops for early-career computational researchers in London. This month, single-cell analysis!

eventbrite.com

Thanks to the discovery of sodium channels and experiments in giant squid 🦑 and much more in between, we now have a non-addictive pain treatment 💊 Brilliant storytelling of why long term funding of basic science across disciplines is critical.

Jeremy Berg@jeremymberg.bsky.social · last yr.

I have been trying to find the time to move away from the polical hellscape we find ourselves in to finish and share a bluetorial about science. This helps me remember what this is all about. Ironically, it is about the treatment of pain.

Just very happy to have our paper out today! A big thanks to all our co-authors, and to Nikolai and @steinaerts.bsky.social for the teamwork over the past years. If you are interested in using our models for cross-species enhancer studies, check out crested.readthedocs.io/en/stable/mo... 🙂

VIB.AI@vibai.bsky.social · last yr.

In a new study, Nikolai Hecker, Niklas Kempynck et al. in the team of @steinaerts.bsky.social explore 300 million years of brain evolution through the lens of enhancer codes. www.science.org/doi/10.1126/...

Londonomics has made the move over to Bluesky 🦋 We now have 200+ members and we’re excited to bring you together at workshops, networking events, and the annual symposium! 💡 We’ll be kicking things off with a NextFlow workshop in March 👀

@londonomics.bsky.social · last yr.

Hi! We’re the Londonomics Network - a network for early career computational researchers (ECCRs) based in London 🇬🇧 We host monthly events including co-working sessions, socials, and workshops 🧑‍💻👩‍💻 Register for free to be a member: www.londonomics.co.uk Stay tuned for our next event in March 💡

Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease? I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵

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Friends and colleagues, I’ve written a book on effective functional genomics study design, which will be available on Amazon in a couple of weeks. Sharing the TOC to spark interest. I hope students and those planning genomics experiments will find it useful! I’ll share updates soon

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What do GWAS and rare variant burden tests discover, and why? Do these studies find the most IMPORTANT genes? If not, how DO they rank genes? Here we present a surprising result: these studies actually test for SPECIFICITY! A 🧵on what this means... (🧪🧬) www.biorxiv.org/content/10.1...

Specificity, length, and luck: How genes are prioritized by rare and common variant association studies

Standard genome-wide association studies (GWAS) and rare variant burden tests are essential tools for identifying trait-relevant genes. Although these methods are conceptually similar, we show by anal...

biorxiv.org