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Landon Getz

@landongetz.bsky.social

PostDoc in The Maxwell Lab at the University of Toronto. PhD. CIHR and EPIC-GSK Postdoctoral Fellow. | He/Him 🏳️‍🌈 Co-Founder of Pride in Microbiology | Saamis(Prairies) ➡️ Kjipuktuk(Halifax) ➡️ Tkaronto(Toronto).

85 Posts864 Follower407 Folgt
Dor Salomon@drdorsalomon.bsky.social · 2d ago

Preprint 🦠🚨: We are diving deeper into #T6SS effectors, and now in #Pantoea. We describe the largest, most diverse effector arsenal associated with a single T6SS, and it's in a plant pathogen that forms galls on beet roots. Sweet! 1/8 www.biorxiv.org/content/10.6...

Pantoea agglomerans T6SS effectors reside in hotspots with combinatorial offensive and defensive arsenals

Gram-negative bacteria deploy type VI secretion systems (T6SSs) to mediate interbacterial competition. Although numerous T6SS effectors have been identified, their pan-genomic repertoires and evolutio...

biorxiv.org

Rafael Pinilla-Redondo (Rafa)@rafomics.bsky.social · 2w ago

1/4 Every good defence needs a backup! 🛡️⚔ Out now in @natrevmicro.nature.com our Comment on "𝗶𝗺𝗺𝘂𝗻𝗲 𝘀𝗮𝗳𝗲𝗴𝘂𝗮𝗿𝗱𝗶𝗻𝗴"! 🎉 🔗 www.nature.com/articles/s41...

Immune safeguarding as a conserved principle of antiviral defence - Nature Reviews Microbiology

All organisms defend against viral infections through active immunity mechanisms that clear the virus or population-level mechanisms that cause regulated cell death. Recent research increasingly shows...

nature.com

Cell Host & Microbe@cp-cellhostmicrobe.bsky.social · 2w ago

A family of lanthipeptides with anti-phage function Discovery of 2,000+ lanthipeptide biosynthetic gene clusters with anti-phage potential. Lanthivirins inhibit phage replication by targeting phage proteins & interfering with phage DNA replication. www.cell.com/cell-host-mi...

A family of lanthipeptides with anti-phage function

Shomar, Guillaume, et al. report the genomics-driven discovery of a family of more than 2,000 lanthipeptide biosynthetic gene clusters with anti-phage potential. They experimentally demonstrate anti-p...

cell.com

@yuxuan-xi.bsky.social · 4w ago

Our new preprint is out! Using AI-guided design (RFdiffusion + ProteinMPNN), we engineered a plant immune receptor to recognise non-cognate pathogen effectors. Huge thanks to our amazing co-authors for making this possible! doi.org/10.64898/202...

Computational design of de novo integrated domains enables rational control of pathogen effector recognition in plant NLR immune receptors.

The rapid evolution of plant pathogens poses a persistent threat to global agricultural sustainability, often outpacing the discovery and deployment of natural disease resistance genes. While bioengin...

doi.org

@artemisaev.bsky.social · 4w ago

Thrilled to share! We present the structure of a prototypical P2 OLD and reveal that its tRNAse activity is triggered by ssDNA hairpins in phage origins or unresolved termini in RecBCD-deficient cells. Great team effort with Wang, Bikard & Nudler labs. www.biorxiv.org/content/10.6...

OLD sentinel: an abortive tRNase surveys phage replication and DNA defects in RecBCD-compromised cells

OLD, an abortive immunity protein from prophage P2, consists of an ABC ATPase sensor and a TO-PRIM nuclease effector - a core architecture shared by a large protein family, including components of ant...

biorxiv.org

Kevin Forsberg@kvnforsberg.bsky.social · last mo.

Humans and bacteria share strategies to defend against viruses. We wondered: could they use each other's genes? Yes, both can! Bacteria can use human immune genes to defend against phages AND Human cells can use bacterial genes for viral defense. www.biorxiv.org/content/10.6...

Bacterial and human exonucleases mediate interkingdom antiviral immunity

All kingdoms of life have developed strategies to limit viral infection. In humans, interferons induce a suite of antiviral factors that collectively provide immunity. Some human immune genes are homo...

biorxiv.org

KDE@kde.org · last mo.

As Pride Month 🏳️‍🌈 draws to its conclusion, KDE and @gnome.org want to pay tribute to LGBTQA+ people that have contributed and continue to contribute to making our lives better through their work in the field of digital technology. We start with one of the greatest computer scientists of all time...

David K Smith@professor-dave.bsky.social · 2mo ago

Currently finalising an article with a biography. Shocked to see that in proof setting, the editor, 'for clarity', changed my dead husband to a 'wife' - I've had to fix it back in the proof. The biography even notes I'm LGBT+ - they apparently don't believe two men can be parents. #LGBTSTEM #GayDad

David Smith was educated at the University of Oxford, carried out postdoctoral research at ETH Zurich and has been an academic at University of York since 1999. In recognition of his research team's work on LMWG hydrogels, he was awarded the prestigious RSC ‘Tilden Prize’. He also received the SCI ‘Science for Society Award’ for chemical education and outreach. Dave has engaged widely on wide-ranging aspects of inclusion and diversity, being named on Attitude Magazine's ‘101 List’ of influential LGBT + figures (2026). Since the death of his wife (they changed this from husband - I have had to change it back) in 2019, Dave has worked part-time and is a single parent to their son.
Jack Bravo@jpkbravo.bsky.social · 2mo ago

Very happy to share this preview article written by my postdoc Danny on exciting recent work from @ostermanilya.bsky.social and @soreklab.bsky.social. New bacterial immunity, phage countermeasures, and a double pun combo in the title.

Cell Host & Microbe@cp-cellhostmicrobe.bsky.social · 2mo ago

NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back Preview of work IDing aRES, bacterial proteins that deplete cellular NAD+, generating products that cannot be utilized by phage NAD+ regeneration pathways www.cell.com/cell-host-mi...

Felix Gunawan (he/him) 🇨🇦🇩🇪🏳️‍🌈@gunawanlab.bsky.social · 2mo ago

In time for Pride Month! In a Q&A with @slefkopoulos.bsky.social and @natcellbio.nature.com, I had the privilege of sharing my personal journey as an LGBTQIA+ immigrant from Indonesia to Canada and Germany. #PrideinSTEM (a mini thread) Link to read (pdf): rdcu.be/fnXyK

A scientist can come from anywhere - Nature Cell Biology

This June, we celebrate Pride by discussing with Felix Gunawan, assistant professor at the University of Toronto and co-affiliate group leader at the University of Münster, about his personal and acad...

nature.com

MichaelMcMurray lab@mcmurraylab.bsky.social · 4mo ago

Doing the periodic cleaning of used plasmid miniprep columns and realized in honor of Earth Day it may be worth reminding you molecular biologists: Plasmid miniprep columns can be cleaned and reused essentially indefinitely! Just add 1 M HCl, soak overnight and wash 3x w/ water. Save $ and plastic

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Landon Getz@landongetz.bsky.social · 4mo ago

Very proud to see where this network has taken us. Its just so lovely to see your ideas in the real world, and we could not have done it with all of our vocal supporters!! There's more to come, we are excited for the future of @prideinmicro.bsky.social !

Pride in Microbiology@prideinmicro.bsky.social · 4mo ago

We are truly overflowing with joy today as Dr. Landon Getz, Dr. Bruno Oliveira, and Dr. Edel Lopez accepted the Microbiology Society's 2026 EDI Award in Belfast at the 2026 Microbiology Society Annual Conference! Dr. Getz also presented an overview of our organization to the conference's attendees!