Liam Browne

@liamebrowne.bsky.social

Associate Professor at UCL interested in pain and threat. Investigating cortical mechanisms and neural interfaces for chronic pain.

📣 We're hiring a postdoc in my lab at UCL! Help develop closed-loop neurotechnology for chronic pain by combining long-term neural implants and recordings with real-time adaptive control in mice. Closes 24 July — please repost or share widely.

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk

Our paper is out! Work by Christopher Black in collaboration with Liam Browne, Rob Brownstone, and Marco Beato. Here, we describe the unique kinematic signatures of multi-limb coordination in freely climbing mice and show how these flexibly adapt to changing environments. tinyurl.com/4bnw88wk

Naturalistic climbing reveals adaptive strategies for interlimb coordination in freely moving mice

Multi-limb coordination is vital for mammalian locomotion. While coordination requires reliable organization of limb movements, it also requires flexibility to adapt to environmental demands. In natur...

tinyurl.com

Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!

The Francis Crick Institute@crick.ac.uk · 10mo ago

We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme. 🔬🩺 Apply by 14 November 2025. 👇 www.crick.ac.uk/careers-stud...

We are proud to launch what we think is going to be fantastic opportunity for pain neuroscientists and clinicians to learn the foundations of pain neuroscience

Nuffield Department of Clinical Neurosciences@ndcnoxford.bsky.social · 10mo ago

September is #PainAwarenessMonth, and we are excited to be launching our brand-new MSc in Pain Neurosciences. Could you help shape the future of #pain research? Opening soon for 2026 admissions 👀 Learn more 👇 bit.ly/OxMScPain

New MSc in Pain Neurosciences. Ready to shape the future of pain research? Applications open soon for 2026 admission.

New preprint out from the lab. We identified three critical windows over which sensorimotor behaviours can be shaped. Altered early experience over these windows changes somatosensory and motor outcomes for life. Tour de force experiments by Laura Andreoli. @medresfdn.bsky.social @uclnpp.bsky.social

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 11mo ago

Discrete and sequential critical periods organise the development of task-specific sensorimotor circuits in mice https://www.biorxiv.org/content/10.1101/2025.09.18.676788v1

We've found a new gene linked to chronic pain in humans! The gene SLC45A4 encodes (the long-awaited) neuronal polyamine transporter, which is important for pain signalling in nerves. We hope this discovery might lead to new chronic pain treatments in the future! www.nature.com/articles/s41...

SLC45A4 is a pain gene encoding a neuronal polyamine transporter - Nature

The SLC45A4 gene encodes a neuronal polyamine transporter and is linked to pain response in humans and mice.

nature.com

We are super excited about the first human transcranial ultrasound study from our lab which is now on BiorXiv, showing the amygdala‘s role in processing ambiguous emotions and showing TUS changed resting-state connectivity and metabolite concentrations (GABA) in the amygdala - a huge team effort! 🥳🙏🏼

Johannes Algermissen@johalgermissen.bsky.social · 12mo ago

Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)

1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex: www.biorxiv.org/content/10.1... I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction. But... 🧠📈 🧪

Sensory responses of visual cortical neurons are not prediction errors

Predictive coding is theorized to be a ubiquitous cortical process to explain sensory responses. It asserts that the brain continuously predicts sensory information and imposes those predictions on lo...

biorxiv.org

Maps are everywhere in the brain...and finally we've discovered one in the nose! Led by @davidhbrann.bsky.social, we uncovered the logic that specifies the positions of each of the 1,000 sensory neuron subtypes in the nose and aligns their projections to the brain.👇👃see more details below👃👇

A spatial code governs olfactory receptor choice and aligns sensory maps in the nose and brain

Although topographical maps organize many peripheral sensory systems, it remains unclear whether olfactory sensory neurons (OSNs) choose which of the ~1100 odor receptors (ORs) to express based upon t...

biorxiv.org