Best news ever- I have finally earned my PhD in Neuroscience!!🧠 My thesis was completed in the lab of Dr. Gregory Corder @flybottleescape.bsky.social & is titled: “Opioidergic Organization of the Nociceptive Medial Thalamus & A Behavioral Model of Placebo Analgesia”

NINDS has discontinued our F32 mechanism. All previously submitted applications will proceed as normal. grants.nih.gov/grants/guide...

Congrats, Matt and team! 🔥 🍾 Stoked that @bakspace.bsky.social and I could collab w yall 👇🏼 Activity capture + chemogenetic reactivation of a placebo analgesia ensemble in the vlPAG is sufficient to drive pain relief on demand … via input from mPFC and outputs to RVM ! 💊 🧠 ⚡️

Matt Banghart@mattbanghart.bsky.social · 4mo ago

Excited to share our new study on how the brain generates placebo pain relief! We developed a mouse model that recapitulates key features of human placebo analgesia, then used it to identify causal circuitry. www.sciencedirect.com/science/arti... today.ucsd.edu/story/neurob... 1/n

New research out in @currentbiology.bsky.social finds that heart rate & sleep history encode ultradian REM sleep timing ft. L. Hao, J. Woolley, Z. Yin, X. Jin, J. Stucynski, R. Adaia, @flybottleescape.bsky.social, S. Chung & F. Weber (Neuroscience) www.sciencedirect.com/science/arti...

Had such a great time presenting my PhD research at this year’s US Association for the Study of Pain conference in Philadelphia. @usasp.bsky.social #neuroskyence #painresearch

Research Highlight: Targeting the affective dimension of pain www.nature.com/articles/s41...

Nature@nature.com · 7mo ago

Nature research paper: Mimicking opioid analgesia in cortical pain circuits go.nature.com/3L6vhCd

The Stanford Encyclopedia of Philosophy just published a revised entry on Animal Consciousness! By Michael Trestman, Jonathan Birch, Colin Allen @wileyprof.bsky.social @birchlse.bsky.social plato.stanford.edu/entries/cons...

!!!!! TENURE !!!!!

By splitting #pain into its component parts, researchers provide pain relief in #mice. In PNAS Journal Club: https://ow.ly/eHT750Y1eGh #ChronicPain #opioid #MachineLearning #AnteriorCingulateCortex

🧠⚡️💊New @nature.com publication ! Mimicking opioid analgesia in cortical pain circuits We built a brain-behavior framework to decode spontaneous chronic pain in mice—and to biologically mimic morphine with a synthetic opioid gene therapy nature.com/articles/s41... @pennmedicine.bsky.social

Nature@nature.com · 7mo ago

Researchers identify the neurons involved in the emotional distress associated with pain go.nature.com/4qIKkB8

Researchers identify the neurons involved in the emotional distress associated with pain go.nature.com/4qIKkB8

Chronic pain could be eased by uncoupling the sensory and emotional experiences

Researchers identify the neurons involved in the emotional distress associated with pain, and design a genetic approach that could soothe suffering without opioid drugs.

go.nature.com

Identity of neurons involved in the emotional distress associated with pain yields genetic approach that could soothe suffering without opioid drugs @nature.com www.nature.com/articles/s41... @flybottleescape.bsky.social @upenn.edu @cmu.edu @yttrilab.bsky.social www.nature.com/articles/d41...

Hot off the @nature.com press!! Our A-SOiD behavior library developed specifically for pain to quantify a new chemogenetic gene therapy that targets opioid circuit in ACC without addictive properties @flybottleescape.bsky.social @cmu-neuroscience.bsky.social @cmu.edu www.nature.com/articles/s41...

Mimicking opioid analgesia in cortical pain circuits - Nature

The anterior cingulate cortex encodes affective pain behaviours modulated by opioids; targeting opioid-sensitive neurons through a new chemogenetic gene therapy replicates the analgesic effects of mor...

nature.com

✨New Corder Lab preprint 🧠⚡️ - from Dr Sophie Rogers ! Differential modulation of aversive signaling by expectation across the cingulate cortex We image the same ACC + RSC neurons over time during noxious fear learning to ask: who encodes aversion vs who predicts it 🔮 biorxiv.org/content/10.6...

Happy yearSEVENversary to our Lab !!!!!!! (still pre-tenure) last year was finally our big paper publishing year but we've got a bunch more cool preprints coming soon :)

"Mason’s criticism of the prosocial behavior field as a whole: It 'has a little bit too much of a pony in the race.' The job of science is to discover, not pick and choose the explanations that are preferred, she adds." www.thetransmitter.org/empathy/up-a...

Up and out with Peggy Mason

Mason helped define the rodent prosocial behavior field, but now she’s changing course.

thetransmitter.org

If you start 'Phantom Thread' at exactly 10:14:47PM on New Year's Eve, you will ring in the New Year with Reynolds Woodcock 🎉🍾🥂🍄‍🟫

🧠🐭💊 Check out our work on the role of Central Amygdala cell-types in opioid withdrawal ... Now published in Neuropsychopharmacology @npp-journal.bsky.social Open-access link: www.nature.com/articles/s41...

Central amygdalar PKCδ neurons mediate fentanyl withdrawal

Neuropsychopharmacology - Central amygdalar PKCδ neurons mediate fentanyl withdrawal

nature.com

⚡️GREG_CORDER⚡️@flybottleescape.bsky.social · last yr.

On behalf of my BSky-less student, Lisa Wooldridge: 🐭🧠💊⚡️ "Thrilled that my PhD work is on bioRxiv! I study how central amygdala (CeA) neurons contribute to opioid effects, but how specific CeA cell types drive this process remains unclear" 🧵 www.biorxiv.org/content/10.1...

Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...

Locus coeruleus norepinephrine neurons facilitate orbitofrontal cortex remapping and behavioral flexibility

Ogg et al. use in vivo imaging techniques to record activity in the locus coeruleus (LC) and the orbitofrontal cortex (OFC) during a reversal learning task in freely moving rodents. They show that man...

cell.com

Now officially: Dr Rogers🎓✨ Unofficially: still the same Sophie.. with more letters + even more legend 🧠🍄💥 You crushed your thesis defense with equal parts science and soul. From psilocybin/psychedelics to pain + aversive processing in cortex you brought rigor, clarity and creative Congrats 🍾

Check out this amazing recognition for all of Lindsay’s amazing efforts in scicom!!! 🙌🏼🔥🎉🤘🏽🫡🍾

Lindsay🧠@neuromelody.bsky.social · 9mo ago

BEST DAY EVER!!! The award is called the Eric & Wendy Schmidt Award for Excellence in Science Communications & is run by @nationalacademies.org & @schmidtsciences.bsky.social #scicomm #phdstudent

@sfn.org Come say hi to postdoc Blake Kimmey Tues, Nov. 18, 8:00 AM - 12:00 PM PSTR278.07 - Convergent state-control of endogenous opioid analgesia He's got new behavior/DREADD/Xenium data on PAG-to-thalamic circuits in pain/placebo/fear, building from his preprint: biorxiv.org/content/10.1...

Sophie Rogers of the Corder @flybottleescape.bsky.social lab studies how a psychedelic drug with growing therapeutic promise can alter the brain in ways that help overcome traumatic fear memories. Read more in this brief by fellow NGG student Jafar Bhatti! www.upennglia.com/briefs/bib-p...

How psychedelics remap the brain to help overcome traumatic fear — GLIA

or technically, Psilocybin-enhanced fear extinction linked to bidirectional modulation of cortical ensembles [See original abstract on Pubmed]

upennglia.com

become my colleague at penn bioengineering: apply.interfolio.com/173716

We could always get some re-interpretation language from NIH but at present the "council in a calendar year" is pretty dang clear. For 2026 Councils, we can submit six apps between May 2025 and March 2026.

🙏 Please help! ad nauseam topic but for new NIH n=6 submission policy is it: a. 6 subs in 2025 calendar year = we can sub 6 R01s for Oct '25 + another 6 for Jan-Dec '26? b. subs in Oct '25 w/ May '26 Council = we can sub 6 R01s Oct '25 to June '26; count resets Oct '26?

Have you ever wondered how some of the leaders in the pain field got their start? Check out this essay from @painthejournal.bsky.social about PRF editorial board member, Allan Basbaum, to learn how he became the journal’s 3rd Editor-in-Chief bit.ly/3JIJTXf #PRF #PainAwarenessMonth

My new essay for @thetransmitter.bsky.social. Why is understanding emotion so challenging? The debates around what counts as an "emotion" shed insight. These disputes are multidimensional, principled and fascinating. Here, I unpack them. www.thetransmitter.org/the-big-pict...

Emotion research has a communication conundrum

In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13…

thetransmitter.org