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Lisa Buchauer

@libuchauer.bsky.social

Computational Biologist. Mathematical models, omics methods and data analysis for immunology and infection research at Charité Berlin. https://buchauer-lab.eu

45 Posts790 Follower926 Folgt
Adlung Lab@adlunglab.com · 9mo ago

We care a lot about time. Now one of my best science friends, Melania Barile, et al. introduce TemporalVAE, a deep generative model that maps scRNA-seq data onto developmental time! It works with zero-shot & identifies time-sensitive genes @natcellbio.nature.com 🧪

TemporalVAE: atlas-assisted temporal mapping of time-series single-cell transcriptomes during embryogenesis

Nature Cell Biology - Liu et al. present TemporalVAE, a method for integrating single-cell time course data. The model proposes a workflow to determine the biological timing of samples and its...

doi.org

Dominic Grün@dominicgrun.bsky.social · last yr.

Few dates left to apply for this tenure-track professorship on Single-Cell Systems Biology in my department at @uni-wuerzburg.de. Competitive package and highly attractive research environment at the Institute of Systems Immunology.

Dominic Grün@dominicgrun.bsky.social · last yr.

We have an attractive opening for a tenure-track professorship in Single-Cell Systems Biology. Excellent package and infrastructure at @uni-wuerzburg.de Institute of Systems Immunology. Great place to live and work in the heart of the franconian wine region! jobs.sciencecareers.org/job/673667/j...

Saez-Rodriguez Group@saezlab.bsky.social · last yr.

Postdoc position in our group at @ebi.embl.org about analyzing single cell data sets to better understand and treat neurodegen diseases, in collab with A Bassett, M Lotfollahi, @bayraktarlab.bsky.social, M Strauss and others within Open Targets. Deadline 20/07. Please share tinyurl.com/87wj466m

Postdoctoral Fellow in computational modelling of NeuroImmune Mechanisms of Neurodegeneration (Open Targets)

Your role As a Postdoctoral Fellow on the NeuroImmune Open Targets project, you will develop and apply integrative computational pipelines to dissect immune-cell phenotypes and cell–cell interactions ...

tinyurl.com

Saez-Rodriguez Group@saezlab.bsky.social · last yr.

We have a curator position at @ebi.embl.org to work with GSK within a project to understand fibrotic processes (no PhD required). Deadline 20th July. Please share 🙏 embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Scientific Database Curator – Fibrosis Transcriptomics

We are seeking a technically skilled and biologically literate Scientific Database Curator to join a focused initiative on fibrosis research, hosted at EMBL-EBI in collaboration with the Saez-Rodrigue...

embl.wd103.myworkdayjobs.com

Lisa Buchauer @libuchauer.bsky.social · last yr.

We are currently recruiting a bioinformatics/computational biology postdoc to join the infrastructure project of a newly funded large research consortium (SFB-TRR) on Circadian Medicine between Charité - Universitätsmedizin Berlin and Universität zu Lübeck ⌚ ⏰ ⏱️ 🕰️ !

Leif Erik Sander 🇪🇺🇺🇦@sanderlab.bsky.social · last yr.

US terminates its support for @gavi.org the vaccine alliance that supplies life-saving vaccines the world’s poorest. Vaccines are among the safest, most effective prevention measures ever introduced. This is a disastrous and short-sighted decision!

US to stop financial support of global vaccine alliance Gavi, health secretary says

Health Secretary Robert F. Kennedy Jr said on Wednesday that the U.S. government will no longer contribute to Gavi, accusing the group that helps buy vaccines for the world's poorest children of ignoring safety, without providing evidence.

reuters.com

Lisa Buchauer @libuchauer.bsky.social · last yr.

decoupler has been very useful for us & helps you dive into meaningful sc analysis quickly! small suggestion to increase uptake: consider changing the logo, at least two python users here initially immediately closed the tab as they thought is was an R package🙃

Saez-Rodriguez Group@saezlab.bsky.social · last yr.

🔧 decoupler 2.0.6 is out thanks to @paubadiam.bsky.social‬, now as a core @scverse.bsky.social package scverse.org This release includes a streamlined API aligned with scverse standards, updated vignettes, and a new one on pseudotime enrichment analysis 👇 decoupler.readthedocs.io/en/latest/

Christian Gaebler@cgaebler.bsky.social · last yr.

Honored that our lab made the shortlist for Best Research Environment. Awesome initiative by Junge Akademie and proud of the incredible Gaebler Lab team and the entire Infectious Disease Department at Charité/BIH that makes this place what it is! 👏 @libuchauer.bsky.social @sanderlab.bsky.social

Die Junge Akademie@jungeakademie.bsky.social · last yr.

🦠 Das Department Translationale #Immunologie viraler #Infektionen an der Charité Berlin und am @bihatcharite.bsky.social ist mit 23 weiteren Teams im Lostopf für das „Beste Forschungsumfeld". Mehr zum Preis und den Teams hier lesen: 👉 www.diejungeakademie.de/de/projekte/...

Rundes Logo von GAEBLER LAB for translational immunology of viral infections. Es zeigt stilisierte Zellbestandzeile. Bildrechte bei AG Gaebler.
Adlung Lab@adlunglab.com · last yr.

🚨 Preprint Alert! New work from the group! 🟤 We set out to explore how brown adipose tissue (BAT) adapts to cold. 🧬🖥️ Using single-nucleus mRNA-sequencing, we dissected murine BAT and uncovered distinct adipocyte subtypes. 🫓 One in particular stood out... 🧵 1/7

Wolfgang Huber@wkhuber.bsky.social · 2y ago

How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3) doi.org/10.1038/s415...

Analysis of multi-condition single-cell data with latent embedding multivariate regression - Nature Genetics

Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...

doi.org