Super excited to share my postdoctoral work at @imbavienna.bsky.social @viennabiocenter.bsky.social - We discovered that some retrotransposons, or "jumping genes" 🧬, are able to spread from cell to cell via a new viral infectivity route. A short thread: 🧵👇 (1/7)

Finally a more intuitaive way to learn pLDDT/pAE? 😎 sokrypton.github.io/protein_figh... (Character idea from @hannes-stark.bsky.social & Alex Waldherr)

Happy to share our new preprint on the structure of the human mitochondrial RNA degradosome, a central player in organellar RNA metabolism! Work led by graduate student @paulafprado.bsky.social in our group. www.biorxiv.org/content/10.6... 🧵 1/9

Holy moly, @ensembl.org killed biomart! Hope many R scripts are there out there that depend on biomaRt? How many people have informatics practicals, or undergraduate project instructions that depend on a web interface for bulk selection of data?

Spatially varying mRNA decay contributes to sharpening the even-skipped expression pattern in the Drosophila embryo #Drosophila

I wrote this quickly at a bus stop and didn't realize it would go viral, or else I would have worded it better. But the point is that the media is too credulous about AI killing everyone in 10 years (how?) when climate change is killing people now and will only get worse (we know exactly how).

David Ho@davidho.bsky.social · 3w ago

I resigned from ExxonMobil today. I spent the last three years doing fossil fuel extraction research at both BP and ExxonMobil. Neither company is acting responsibly. They are racing to maximize extraction while the window to act closes, and gambling with our lives. More below.

“… The studies they were carrying out were full of underlying philosophical assumptions. (…) If your characterization of a term is wrong, you will ask the wrong questions, look in all the wrong places, and ultimately mischaracterize the world.”

Susana Monsó@susanamonso.com · last mo.

I wrote a little something on the value of philosophy for animal cognition. Out now in Science’s Expert Voices column.

‼️ Postdoc position open. We study how protein metabolism controls time. If you’re excited by this question, we’d love to hear from you! We’re looking for a motivated & collaborative researcher with a strong track record. 📅 30 September 2026 📢 Please share Apply here 👇👇

Postdoctoral Research Scientist - Babraham

The lab investigates the molecular mechanisms that control biological timing in mouse and human stem cells (Azzi & Rayon, Curr Opinions 2024; Nakanoh et al., Dev Cell 2026). The central aim of this ex...

babraham.current-vacancies.com

📰Happy to share our preprint.🥳Here we investigate🔬, the essential role of the conserved RNA helicase Drs1. We show that its engagement and activity license timely incorporation of 25S rRNA domain III into maturing nucleolar pre-60S subunits.👇 doi.org/10.64898/2026.09.05.749353 #cryoEM #ribosome #RNA

Did you know that the cells of old animals contain much less mRNA than the cells of young ones? Let me share with you some results from an ongoing project in the lab, where we are finding that a progressive depletion of total mRNA abundance is a crucial part of aging 1/22

AlphaFold Server’s ligand menu just got a lot bigger and I almost missed it! You can now add any ligand from the wwPDB Chemical Component Dictionary. Just enter its CCD code 🥳

We are recruiting a PhD student 🥼🙋 Topic: how germ cells bend gene expression dogmas Fly genetics + proteomics + genomics. Fully funded. Aarhus University 🇩🇰 info on the project and how to apply👇 mbg.au.dk/en/peter-and... I'd really appreciate it if you'd help spread the word. Thanks

A transient RNP compartment boosts translation and growth of mammalian oocytes | Science Advances www.science.org/doi/10.1126/...

A transient RNP compartment boosts translation and growth of mammalian oocytes

Mammalian oocytes undergo an extended growth phase, during which transcription gradually declines. To sustain meiotic divisions and early embryonic development, growing oocytes must accumulate materna...

science.org

Pre-print alert! SERBP1 regulates the interactions between ribosomes and different proteins. We find that it prevents interactions between ribosomes and RNF10/RIOK3 to protect ribosomes from selective 40S degradation. Congrats! @nicollearosa.bsky.social www.biorxiv.org/content/10.6...

SERBP1 is a master regulator of ribosome interactions

Ribosome function depends on interactions with diverse proteins whose activities determine translational efficiency, impose quality control and activate signaling pathways. These many competing activi...

biorxiv.org

We watched piRNAs and transposons across development, saw them dance tightly and wrote a paper about it. It's so cool to see it online and we will make a thread about it all very soon. Stay tuned :-)

bioRxiv Genetics@biorxiv-genetic.bsky.social · last mo.

A developmental switch in the piRNA pathway ensures stage-specific transposon silencing https://www.biorxiv.org/content/10.64898/2026.08.28.747770v1

If you're looking for a REALLY active protein kinase, they found one. Crazy stuff www.nature.com/articles/s41...

Pervasive phosphorylation by phage T7 kinase disarms bacterial defences - Nature

The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.

nature.com

Foldseek-Interface enables fast search/clustering of the protein interface universe! We clustered 3.1M PDB dimers into 77,167 groups and found new interfaces keep appearing even as fold discovery plateaus. 🧵 📄 www.biorxiv.org/content/10.6... 🔎 search.foldseek.com/interface 🌐 interface.foldseek.com

In an amazing collaboration with the Steinegger lab we developed Foldseek-Interface and clustered the resolved protein interface universe revealing structural bias, pathogen mimicry and novel interface structures in predicted protein complexes. doi.org/10.64898/202...

NIH Intramural Research Program is hiring via the Stadtman program. Prospective candidates should feel free to reach out to me, and I will be happy to share my experience both as an applicant and a panel member- we are looking for great new colleagues! irp.nih.gov/careers/nih-...

The Spanish dancer (Hexabranchus sanguineus) is a very large crimson to blood-red dorid nudibranch (sea slug) of the Indo-Pacific, named for the flamenco-like way it swims by undulating its flared mantle. That absolutely DOES look like a flamenco dancer's skirt!

Finally caught a decent video of a comb jelly in action! This is Bob, the biggest one in our facility. Bob underwent reverse development due to stress & transitioned from an adult (lobate) back to a larva (cydippid). Now Bob is developing back into a lobate again! Science is so cool 🤩 #ctenophore

What happens when evolution adds an extra pair of eyes? Male mayflies evolve an extra pair of dorsal compound eyes, the Turbanate eyes, thought to help males detect females during mating swarms. we have investigate how this remarkable evolutionary novelty develops. www.biorxiv.org/content/10.6...

I will be opening my research group at the Max Delbrück Center later this year to unravel the principles governing the unique context sensing capacity of the liver www.mdc-berlin.de/schwayer and am looking for enthusiastic PhD applicants.

Schwayer Lab

The mammalian liver possesses a regenerative capacity that is unmatched by any other organ. Following injury, liver epithelial cells can proliferate or even change their identity, enabling the organ t...

mdc-berlin.de

Did we say we really love this idea? Apply, if keen! #zebrafish

International Zebrafish Society@izfs.bsky.social · 2mo ago

NEW GRANT OPPORTUNITY! Ever wanted to travel to a different lab to learn more? Or expand your knowledge and experience in the field? #IZFS has a new grant opportunity for you! Read more about the Knowledge Exchange Grant here: www.izfs.org/awards/knowl... #ZebrafishGrant

Out in @natplants.nature.com, mapping of brassinosteroid chemical features required for (1) receptor binding, (2) ligand positioning and (3) co-receptor recruitment. Fantastic work by Alberto Caregnato & @hmchen93.bsky.social and our friends in Olomouc. Funding:@snf-fns.ch -> doi.org/10.1038/s414...

PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs

A multivalent RNA affinity tag enables selective purification of tagged RNAs and bound proteins doi.org/10.1093/nar/...

A multivalent RNA affinity tag enables selective purification of tagged RNAs and bound proteins

Abstract. Efficient purification of specific RNAs from lysates remains a major challenge. Existing methods, such as MS2 tagging or oligonucleotide hybridiz

doi.org

Check out our new article if you are interested in disorder-mediated protein interactions, AlphaFold-based structural modeling and variant characterization: Https://rdcu.be/fw2oz Dx.doi.org/10.1038/s41594-026-01846-z

Variant characterization in the intrinsically disordered human proteome - Nature Structural & Molecular Biology

Proteome-wide prediction and structural modeling of disordered protein interaction interfaces advance characterization of disease-associated variants in disordered protein regions.

dx.doi.org

We should support junior scientists (the old ones too 😉) and not destroy their self esteem and their passion.

Registration for the 19th meeting of the #SEBD is now open! Please join us at El Rompido for 3 days full of excellent #DevBio and plenty of opportunities to present your work at #SEBD2026 share.google/2llY3VlS5fQA...