If an action results in error, each neuron requires an individualized teaching signal that guides change in its output. This is the credit assignment problem of learning. Are there neurons in the brain that can compute such a sophisticated teaching signal? Yes. www.biorxiv.org/content/10.6...

Climbing fibers encode the gradient of a loss function for the cerebellum

Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of th...

biorxiv.org

@macshine.bsky.social talks with @satra.bsky.social about the #OHBM2026 Abstract Atlas—a community-built tool that places every 2026 abstract inside the broader neuroscience landscape. Where does your work sit in the field? #neuroskyence www.thetransmitter.org/open-source-...

Finding your place in neuroscience

A new tool places every OHBM 2026 abstract inside a semantic map of the neuroscience literature, so you can find your neighbors.

thetransmitter.org

🎉 Registration is now OPEN for the 2026 OHBM Australian Chapter Annual Meeting! 🇦🇺🧠🇦🇺 Get your ticket now! 🎟️🎟️🎟️ Registration: events.humanitix.com/ohbm-austral... 📝 Submit your abstract: docs.google.com/forms/d/e/1F... 🏆 Nominate a colleague (or yourself) for an award: ohbm-aus.github.io/awards/

OHBM Australia Meeting 2026

Uniting the Australian human brain mapping community.

events.humanitix.com

@macshine.bsky.social talks with @melcooperphd.bsky.social about her new work showing that astrocytes—long dismissed as the brain’s housekeepers—are wired together in precise, long-range networks that remodel in response to experience. #neuroskyence www.thetransmitter.org/astrocytes/t...

How a hidden network of astrocytes shapes the brain

Astrocytes are wired together in precise, long-range networks that remodel in response to experience, according to new research.

thetransmitter.org

@macshine.bsky.social talks with Mario Senden about his new project using AI-driven bibliometrics to map the structural organization of neuroscience across 25 years. The field it reveals is at once thriving and theoretically adrift. #neuroskyence www.thetransmitter.org/methods/what...

What a bird’s-eye view of half a million papers reveals about neuroscience

New research uses artificial-intellligence-driven bibliometrics to map the structural organization of neuroscience across 25 years. The field it reveals is at once thriving and theoretically adrift.

thetransmitter.org

fMRI connectivity is dominated by recurring high-amplitude BOLD events (CAPs, QPPs) But what originates these events? Many think neuromodulation is the culprit. Our new work offers a simpler take: cortico-cortical dynamics alone can generate CAP-like events! doi.org/10.1371/journal.pcbi.1013995 🧵1/n

I recently had the pleasure of chatting with @macshine.bsky.social as part of the OHBM Award Winner interview series; thanks for a great conversation! 🙏 Catch the interview here 👇

OHBM Communications Committee (ComCom)@ohbm-com.com · 8mo ago

Each year we have the pleasure of interviewing the OHBM Award Winners 🏆 First up is Prof Mac Shine, winner of the 2025 Early Career Investigator Award! 🌟 @macshine.bsky.social Watch the interview here: www.ohbm-com.com/blog/intervi...

𝗔 𝗡𝗘𝗨𝗥𝗢𝗘𝗖𝗢𝗟𝗢𝗚𝗜𝗖𝗔𝗟 𝗣𝗘𝗥𝗦𝗣𝗘𝗖𝗧𝗜𝗩𝗘 𝗢𝗡 𝗧𝗛𝗘 𝗣𝗥𝗘𝗙𝗥𝗢𝗡𝗧𝗔𝗟 𝗖𝗢𝗥𝗧𝗘𝗫 By Mars and Passingham "Understanding anthropoid foraging challenges may thus contribute to our understanding of human cognition" Going to the top of the reading list! doi.org/10.1016/j.ne... #neuroskyence

random neuroimaging question: does anyone in bluesky-land have access to the loadings for neurosynth topics in schaefer 400 (yeo7) space? #neuroskyence @misicbata.bsky.social @richardfbetzel.bsky.social @borismontreal.bsky.social @sofievalk.bsky.social

*New preprint from the lab* – “Granularity of thalamic head direction cells” doi.org/10.1101/2025... 🧠📈 🧪 1/11

Granularity of thalamic head direction cells

Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...

doi.org

What changes and what stays the same as you scale from single neurons up to local populations of neurons up to whole brains? Michael and Mac @macshine.bsky.social on the systems approach to study brains across scales. braininspired.co/podcast/220/

Excited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social! We asked: How does the motor cortex account for arm posture when generating movement? Paper 👉 www.biorxiv.org/content/10.1... 1/10

Compositional neural dynamics during reaching

The complex mechanics of the arm make the neural control of reaching inherently posture dependent. Because previous reaching studies confound reach direction with final posture, it remains unknown how...

biorxiv.org

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

Theoretical neuroscience has room to grow — a Comment article by Ann Kennedy @antihebbiann.bsky.social #neuroscience #neuroskyence www.nature.com/articles/s41...

I need some help from the #neuroskyence Bluesky-verse. Anyone know the source of this ~quote from Walter J. Freeman Jr.: "the secrets of the brain are hidden by two of God’s own firewalls: neurobiology and non-linear dynamics". I read it yrs ago but can't seem to find my way back to the source.

🚨Pre-print alert🚨 We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭 How is this possible? Strap in! (1/9) 👇🧵 doi.org/10.1101/2025...

Serotonin drives choice-independent reconfiguration of distributed neural activity

Serotonin (5-HT) is a central neuromodulator which is implicated in, amongst other functions, cognitive flexibility. 5-HT is released from the dorsal raphe nucleus (DRN) throughout nearly the entire f...

doi.org

🚨 California and Hawaii under tsunami watch after 8.7M quake in Eastern Russia.

Tsunami Warning – 7/30, 9:40am The Tsunami Advisory has been upgraded to a Tsunami Warning. Waves of up to 3m are expected. Those near coastal areas, rivers, or lakes should evacuate to higher ground immediately. #tsunami

The point is, the monkeys making the loudest noise have the smallest balls. pubmed.ncbi.nlm.nih.gov/26592343/

Evolutionary trade-off between vocal tract and testes dimensions in howler monkeys - PubMed

Males often face a trade-off between investments in precopulatory and postcopulatory traits [1], particularly when male-male contest competition determines access to mates [2]. To date, studies of pre...

pubmed.ncbi.nlm.nih.gov

Dem leadership should appoint an official Alt Press Secretary to give briefings after every one that Karoline Leavett does and just break them down lie by lie maybe THAT’S the job we give Colbert 😂

Kevin M. Kruse@kevinmkruse.bsky.social · last yr.

At this point, you should be embarrassed if your outlet has done nothing over these tumultuous six months to get itself barred by the administration. The Wall Street Journal is speaking truth to power, but you're still on good terms with these assholes? Yeah, be proud of that.

An exciting collaboration is underway. @thetransmitter.bsky.social is partnering with @neuromatch.bsky.social to serve the computational neuroscience community and help connect neuroscientists across all career stages. www.thetransmitter.org/neuromatch-p... #neuroskyence

“the kindest person in the room is often the smartest.” JB Pritzker is a mensch.

Prefrontal axons going to lots of places! doi.org/10.1016/j.ce... #neuroskyence

Pairs well with www.nature.com/articles/s41... “Our results indicate that individual V1 neurons do not signal how the actual visual input deviates from the animal’s predictions, as postulated within the predictive coding framework” Thrilling to see a major theory get tested!

Cooperative thalamocortical circuit mechanism for sensory prediction errors - Nature

Experiments in mice show that a cortico-thalamic circuit generates prediction-error signals in primary visual cortex that amplify visual input that deviates from animals’ expectations.

nature.com

Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social! academic.oup.com/endo/article... 🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic

GLP-1 and the Neurobiology of Eating Control: Recent Advances

Abstract. Obesity is now considered a chronic relapsing progressive disease, associated with increased all-cause mortality that scales with body weight, af

academic.oup.com

I honestly think we should have a screening system for who gets to have money and influence based on asking "what was Star Wars about?" and "who were the good guys?"

Mauricio Sellmann Oliveira@mausellmoli.bsky.social · last yr.

Yes, Peter Thiel is functionally illiterate. Here’s his attempt at summarising the Star Wars plot to Maureen Dowd in 2017: www.nytimes.com/2017/01/11/f...

Molecular and functional diversity of the autonomic nervous system — a Review by Tongtong Wang, Avedis Tufenkjian, Olujimi A. Ajijola & Yuki Oka #neuroscience #neuroskyence www.nature.com/articles/s41...

Molecular and functional diversity of the autonomic nervous system - Nature Reviews Neuroscience

The autonomic nervous system has long been viewed as a simple motor system in brain-to-body signalling. In this review, Wang and colleagues highlight diversity within autonomic neurons and their dynam...

nature.com

Exciting new preprint from the lab: “Adopting a human developmental visual diet yields robust, shape-based AI vision”. A most wonderful case where brain inspiration massively improved AI solutions. Work with @zejinlu.bsky.social @sushrutthorat.bsky.social and Radek Cichy arxiv.org/abs/2507.03168

🚨 New paper in Journal of Vision! We show that scene affordances—what you can do in a space—shape how we perceive and categorize scenes. This shapes your similarity preferences, predicts your categorization false alarms, and even alters neural representations. 🧵👇 🔗 doi.org/10.1167/jov.... (1/7)