New paper alert! Michal Dibus and team show tensin-1 forms reversible condensates that act as reservoirs for adhesion proteins, tuning adhesion turnover and cell migration - a cool new role for phase separation in cell adhesion dynamics! Congratulations to the team 🎉! Paper here: bit.ly/4y9E8Xr

Michal Dibus@midibu.bsky.social · 4w ago

1/5 🎉 Finally, the results of my main postdoctoral project are out in @natcomms.nature.com! Adhesion-derived condensates control component availability to regulate adhesion dynamics bit.ly/4y9E8Xr Also excited to see the paper highlighted in Nat Comms Editors’ Highlights 🥳 bit.ly/44n4O9i

1/5 🎉 Finally, the results of my main postdoctoral project are out in @natcomms.nature.com! Adhesion-derived condensates control component availability to regulate adhesion dynamics bit.ly/4y9E8Xr Also excited to see the paper highlighted in Nat Comms Editors’ Highlights 🥳 bit.ly/44n4O9i

Proud to be part of this cool story by @follainga.bsky.social, led by @guijacquemet.bsky.social and @johannaivaska.bsky.social. Go and have a look!

Guillaume Jacquemet@guijacquemet.bsky.social · 7mo ago

Delighted to share the latest paper from the lab "Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers" Amazing work driven by @follainga.bsky.social with contributions from many. link.springer.com/article/10.1...

We wrote two reviews on cell migration, published today in Nature Methods. They provides practical guidelines how to select a cell-migration assay and how to analyze cell-migration data Review 1: nature.com/articles/s41... Review 2: nature.com/articles/s41...

Latest from the lab "Filopodome proteomics identifies CCT8 as a MYO10 interactor critical for filopodia functions " www.biorxiv.org/content/10.6... Work driven by @anagracanin.bsky.social A great collaboration with @ivaskalab.bsky.social and @bengoult.bsky.social

Filopodome proteomics identifies CCT8 as a MYO10 interactor critical for filopodia functions

Cancer cells utilize filopodia to explore, adhere to, and invade their surrounding microenvironment, yet the protein networks that organize these protrusions remain incompletely defined. To uncover th...

biorxiv.org

Why IDPs Are Poor Candidates for Homotypic LLPS 🧵👇A thread

Research Associate (100%) Starting from 1 November 2025 or as per agreement Group @erikvannimwegen.bsky.social @biozentrum.unibas.ch @unibas.ch www.biozentrum.unibas.ch/open-positio... #job #research #biology #microbiology #science #basel #recruiting #career

Very happy to see our preprint on how the mechanosensitive ion channel Piezo1 controls intercellular junction maturation by balancing cortex and membrane tension now published in @jcellsci.bsky.social Congratulations to Ahsan & team! journals.biologists.com/jcs/article/...

📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Mechanistic Cell and Developmental Biology. More details ➡️ tinyurl.com/3fbkp89c

Excited to share our most recent study on #integrintraffic #cancer #migration #focaladhesion by @ivaskalab.bsky.social @drpaulinamoreno.bsky.social Niklas Jäntti et al www.sciencedirect.com/science/arti...

EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration

Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different c…

sciencedirect.com

Fresh out of @ivaskalab.bsky.social on EPLINs' roles in integrin trafficking! Go have a look! 🎉

Paulina Morlay@drpaulinamoreno.bsky.social · last yr.

Very happy to share Niklas Jäntti's PhD work on EPLIN /LIMA1 isoforms (α/β) in breast cancer (spoiler: both have opposing roles in integrin traffic, cell migration & clinical outcome). This might explain why EPLIN sometimes has been reported as pro- and sometimes as anti-tumorigenic: bit.ly/3Iwjtau

Data drop! We just released an updated list of anti-ECM antibodies curated from the #HumanBioMolecularAtlasProgram Organ Mapping Antibody Panels #OMAP and the 9th release of the Human Reference Atlas #HRA. Check it out: sites.google.com/uic.edu/matr...

Grateful for the poster prize awarded by @febsopenbio.bsky.social at the #FEBS2025 congress! It was a pleasure to meet so many inspiring people and discuss some great science! @ivaskalab.bsky.social

@febsopenbio.bsky.social · last yr.

🏆 Congrats to Michal Dibus for winning the daily poster prize from FEBS Open Bio today with his poster "Tensin 1 phase separation in regulation of integrin adhesion dynamics"👏 @midibu.bsky.social @ivaskalab.bsky.social #FEBS2025 #FEBSCongress2025

Are you looking for a postdoc? I will be looking for 2-4 people after the summer to join the lab !! Do not hesitate to reach out and disseminate !!

- A postdoc to work on cancer extravasation (4-year project). - A postdoc help in completing Filopodia-related lab projects (2-year). - Multiple Marie Curie postdoc positions that will open in the fall. - We will open a 5-year position to cover my teaching (70% research and 30% teaching).

Guillaume Jacquemet@guijacquemet.bsky.social · last yr.

Are you looking for a postdoc? I will be looking for 2-4 people after the summer to join the lab !! Do not hesitate to reach out and disseminate !!

If you are at the FEBS Congress in Istanbul and would like to have a chat about adhesion-derived protein condensates come to see my poster today between 12:30-13:45. Looking forward to inspiring discussions! 🔬 @ivaskalab.bsky.social

What controls condensate composition and function beyond binding stoichiometry? We show that condensate microenvironments play a key role, and can be probed by a micropeptide killswitch in live cells. www.nature.com/articles/s41... in @nature.com ‬ with @yaotianzhang.bsky.social Denes Hnisz & team.

Those little things.. :) @littleprincesses.bsky.social

New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41...

Latest from @ivaskalab.bsky.social @jrwconway.bsky.social in NCB. We find that SHP-2 inhibition stops TNBC invasion and limits metastasis by blocking integrin dephosphorylation! Read more at: www.nature.com/articles/s41...

Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature Cell Biology

Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...

nature.com

We are offering an exciting project for aspiring clinical scientists! Cytoskeletal Dynamics in Circulating Tumour Cells from Breast Cancer Patients! Don't miss this opportunity to work at the interface between fundamental and clinical science @icr.ac.uk 😀! www.icr.ac.uk/study-and-ca...

We are very proud to announce @johannaivaska.bsky.social as the recipient of the Biennial Finnish Science Award, given by the Finnish Ministry of Education & Culture. Johanna was described as a distinguished researcher with pioneering work in cell biology. Warmest congrats from all of us, boss!

Proud to be a part of Johanna's team... Warmest congratulations! :) @johannaivaska.bsky.social www.utu.fi/en/news/news...

Finnish Science Award to Professor Johanna Ivaska

The Finnish Science Award 2025 has been awarded to Johanna Ivaska, Professor of Molecular Cell Biology at the University of Turku.

utu.fi

The feeling when you get back to the lab after a week at a gordon conference - totally inspired and energised after hearing incredible science and meeting amazing people. Thank you @tanentzapflab.bsky.social and @sarawickstrom.bsky.social for GRC Fibronectin, Integrins and related molecules.

Amazed Inspired GIF

Alt: Amazed Inspired GIF

media.tenor.com

Thanks to @tanentzapflab.bsky.social & @sarawickstrom.bsky.social, chairs of an excellent Fibronectin, Integrins & Related Molecules GRC & to @martina-lerche.bsky.social & @mchastney.bsky.social for chairing the GRS. We look forward to Kairbaan Hodivala-Dilke & Tom Barker's 2027 meeting!

Happy to share our Tensin 1 phase separation project is now on bioRxiv. www.biorxiv.org/content/10.1... This wouldn't be possible without @johannaivaska.bsky.social @ivaskalab.bsky.social #VattulainenLab #MSCA by @ec.europa.eu @turkubioscience.bsky.social @inflames-flagship.bsky.social

Adhesion-derived condensates control component availability to regulate adhesion dynamics

Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...

biorxiv.org

Ivaska lab members are at the Fibronectin GRC at the gorgeous Renaissance Hotel in Tuscany! Come say hi to (L-R) Michalis, Megan, Omkar, Gautier and Michal if you haven't already 😀

Currently at Fibronectin and Integrins GRC in Italy, meeting amazing people and discussing great science. If you are interested in Tensin phase separation, come and talk to me! @ivaskalab.bsky.social

We are looking for a doctoral candidate to join the lab! If you are interested in working with human breast tissue samples straight from the clinic and do not fear large data sets, this might just be your dream project ☺️ Apply now ⬇️ ats.talentadore.com/apply/vaitos... 📸 @oonapaavolainen.bsky.social