If you are interested in mitochondria, Nashville is the place to be June 1-5. Check out this FASEB meeting. Please RT. events.faseb.org/event/mitoch...

📢 We have not 1 but 3 clinical/patient-facing jobs working with #mitoCAMB on the #LifeArc #raredisease centre for #mito diseases. 1x pre/post-doctoral CRA; 1x post-doctoral CRA (with potential to become a 4 year ACL); 1x research coordinator Join us! Links below.

Enjoy this week's selection of papers related to #MitochondrialDisease. Congrats to all the authors! 👇 biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitowomen.bsky.social @mitoworld.bsky.social @mitoscientists.bsky.social @mitoscientist.bsky.social

#mitochondrialdisease research from last week! biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoworld.bsky.social @mitowomen.bsky.social Mitofusin 2 displays fusion-independent roles in proteostasis surveillance

Groundbreaking week of research in #mitochondrialdisease! biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitowomen.bsky.social @mitoworld.bsky.social Rhodoquinone carries electrons in the mammalian electron transport chain

Start your week fresh with this outstanding collection of #mitochondrialdisease papers from last week! biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitowomen.bsky.social @mitoworld.bsky.social Hypoxia as medicine

A recent manuscript by @sulianamanley.bsky.social's lab led by @jclandoni.bsky.social describes reversible mitochondrial pearling as a driving force for mtDNA regular distribution within mitochondria. PKmito ORANGE was used in to image mitochondrial pearling by STED microscopy in live cells.

Here is a quick thread to promote my research! After years of dedicated research, I'm thrilled to share our article just published at Nature Communications :) www.nature.com/articles/s41... #metabolism #CRISPRscreens #mitochondria

SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation

Nature Communications - Pyridoxal 5’-phosphate (PLP, vitamin B6) is crucial for various metabolic processes. Here, the authors identified SLC25A38 as a key regulator of mitochondrial PLP...

nature.com

Really interesting paper 🧪 🤩 Immune evasion through mitochondrial transfer 😮 Ikeda et al find that #mitochondria from cancer cells can #transfer over to T cells - altering their #metabolism & reducing antitumour immunity www.nature.com/articles/s41... www.nature.com/articles/d41... @nature.com

Cancer cells ‘poison’ the immune system with tainted mitochondria

Immune cells lose their cancer-fighting prowess after taking tumours’ organelles on board.

nature.com

Last 2 weeks of research on #mitochondrialdisease! biomed.news/bims-mitdis/... biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitowomen.bsky.social Imaging flow cytometry reveals divergent mitochondrial phenotypes in mito disease patients

What a week for mtDNA and mito lovers! @mitowomen.bsky.social

Johanna Joyce@johannajoyce.bsky.social · 2y ago

Really interesting paper 🧪 🤩 Immune evasion through mitochondrial transfer 😮 Ikeda et al find that #mitochondria from cancer cells can #transfer over to T cells - altering their #metabolism & reducing antitumour immunity www.nature.com/articles/s41... www.nature.com/articles/d41... @nature.com

The first collection of papers on #mitochondrialdisease in 2025! @biomednews.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social @mitowomen.bsky.social @gavinmcstay.bsky.social biomed.news/bims-mitdis/... DLK-dependent axonal mitochondrial fission drives degeneration after axotomy

We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all collaborators and the 4th anonymous reviewer for supporting us. @naturecomms.bsky.social www.nature.com/articles/s41...

Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster - Nature Communications

Finding ways to compensate for mitochondrial dysfunction is essential. Here, the authors performed a genome-wide genetic screen to identify genes that mitigate the larvae lethal phenotype of a fruit f...

nature.com

My lab at Emory University in vibrant Atlanta is looking for a postdoc candidate in #mitochondrialbiology and #metabolism! This position offers training opportunities in #metabolomics using our in-house Agilent 6546 QTOF LCMS. Please spread the word! (1/3)

🧪 St. Jude Progress has featured our research as part of their "Best of 2024", based on summary articles they wrote over the course of the year! www.stjude.org/research/pro...

A glimpse beyond life and death: Exploring the biology of the MICOS complex

See why MIC60, a part of the MICOS complex in mitochondria, is fatal when removed, as St. Jude researchers design mouse model to study mitochondrial disruption

stjude.org

Let's start the week at Bluesky with an updated Starter Pack V3.0 #metabolism and #mitochondrialbiology are super strong here! go.bsky.app/VavECSX

#Therapies for #mitochondrial #disorders community. You are welcome to join by commenting below! go.bsky.app/BnMQq9C #therapy #mitochondria #mitochondrialdisease

A long selection of papers this week related to #mitochondrialdisease biomed.news/bims-mitdis/... Many highlights, methods, emerging ideas. Repost and follow for more mito-papers. 🦋 www.nature.com/articles/s41...

HSF-1 promotes longevity through ubiquilin-1-dependent mitochondrial network remodelling - Nature Communications

Increased activity of heat shock factor 1 (HSF1) promotes longevity; however, the mechanisms underlying this are unclear. Here, the authors show that in the nematode worm Caenorhabditis elegans, HSF1 ...

nature.com

Hi all! We’re excited to see this community grow. One of our main goals is to highlight the work and voices of women in mitochondrial research. Please tag us in any relevant posts so we can help to amplify these contributions!!

🔬 Curious about #mitochondria #imaging but unsure where to begin? Our review might help! 🚀📜🧪 www.annualreviews.org/content/jour... #Quantitative #Microscopy #SuperResolution #AcademicSky #ScienceSky #CellBiology #mtDNA

Exciting work from the #wredenberg Lab 🧪 www.biorxiv.org/content/10.1...

The mitochondrial methylation potential gates mitoribosome assembly

S-adenosylmethionine (SAM) is crucial for cellular processes, primarily serving as the principal methyl group donor of the cell and playing a key role in gene regulation and translation on the ribosom...

biorxiv.org

In our latest preprint, we used brain organoids and machine learning to identify new drugs for the mitochondrial disease Leigh syndrome. www.biorxiv.org/content/10.1...

Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease

Mitochondrial disease encompasses untreatable conditions affecting tissues with high energy demands. A severe manifestation of mitochondrial disease is Leigh syndrome (Leigh), which causes defects in ...

biorxiv.org

Excited to share this new preprint from Sierra Palumbos, tracking the effects of dysfunctional autophagy in neurons: www.biorxiv.org/content/10.1...

Autophagic stress activates distinct compensatory secretory pathways in neurons

Autophagic dysfunction is a hallmark of neurodegenerative disease, leaving neurons vulnerable to the accumulation of damaged organelles and proteins. However, the late onset of diseases suggests that ...

biorxiv.org

If you are interested in mitochondria, mitophagy and/or PD follow the mito911 Webinar series! Events calendar and registration at this link parkinsonsroadmap.org/events/

Events

Aligning Science Across Parkinson’s (ASAP) aims to foster collaboration and discovery by supporting virtual and in-person events that facilitate connections and provide an avenue for sharing ideas. Se...

parkinsonsroadmap.org

Links to multiple mitochondria and metabolism starter packs below!

Christian Frezza@frezzalab.bsky.social · 2y ago

People working on #cancermetabolism, #mitochondrialbiology, #metabolism, please reach out! Share this so I can follow who is here! I will share paper on cancer metabolism, but anything else related to mitochondria and metabolism.

Check out our new quick guide in @currentbiology.bsky.social, all about Mitochondrial Nucleoids! t.co/QFTQrevZNu

Check out these MITOchats on Thursday!! www.mitotalks.org for info and Zoom link.

Ewa Bomba-Warczak@ebomba.bsky.social · 2y ago

MITOtalks have not made it here (yet) but we are excited to host two fantastic trainee talks this week on MITOchats - Alia Edington from Friedman lab at UTSW and David Eberhardt from Chaudhuri at UUtah - visit www.mitotalks.org for more info and zoom link to join! #mitochondria please share!

Re-introducing ourselves to the Bluesky community! We aim to highlight research accomplishments performed by women in the field of mitochondrial biology. Also, visit our website, mitowomen.org, to find a list of women studying mitochondria. Please sign up if you haven't already!

Women in Mitochondria@mitowomen.bsky.social · 2y ago

We are excited to expand our platform to Bluesky! Follow @mitowomen.bsky.social for highlights on research performed by women in mitochondrial research. Check out our website for a list of outstanding women in mito research (to invite speakers, recruit students/postdocs, find collaborators, etc)

Trying to find all the metabolism/mito folks on here, so i created a starter pack. Please suggest anyone I missed! go.bsky.app/C2t7snh

We are excited to expand our platform to Bluesky! Follow @mitowomen.bsky.social for highlights on research performed by women in mitochondrial research. Check out our website for a list of outstanding women in mito research (to invite speakers, recruit students/postdocs, find collaborators, etc)