"Precarity is the one constant of academic science. Themes of instability thread themselves through everything we do." A brief blog post from me about the @ukri.org funding pause and who the real victims will be. occamstypewriter.org/mindthegap/2... #AcademicSky
In which we watch and wait | Mind the Gap
occamstypewriter.org
We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad: idm.uct.ac.za/media/739223
👶✈️ Balancing caregiving and academic travel? Join Dr. Laura Pallett for "The Dual Demands of Academic Travel and Caregiving" 🗓️ Sept 25 | 🕒15:00 CEST 🔗https://tinyurl.com/yefis2025-ia2 Hosted by the Improving Academia group of yEFIS
In @elife.bsky.social: Type I interferon responses contribute to immune protection against mycobacterial infection doi.org/10.7554/eLif... #TBSky #IDSky #Immunosky work led by Gillian Tomlinson with support from @mnoursad.bsky.social & @innate2adaptive.bsky.social group (1/5)
Type I interferon responses contribute to immune protection against mycobacterial infection
doi.org
Very excited to share our new piece of work in the Lancet Global Health @lancetgh.bsky.social – Periskope-CM, a set of personalised risk prediction tools for HIV-associated cryptococcal meningitis mortality: www.thelancet.com/journals/lan... #IDsky #HIV #GlobalHealth #meningitis #fungal 1/8
Lancet
thelancet.com
Come on down, anyone eligible for a post-doc do consider applying for this exciting project with @jennyrohn.bsky.social, @scottishwormboy.bsky.social & me! Got a touch of #UTISky #IDSky #ImmunoSky & 🧪 about it! 😉
Prof Jenny Rohn@jennyrohn.bsky.social · last yr.*JOB ADVERT LIVE!* Come be my next MRC-funded postdoc in London, studying uropathogenic E. coli virulence/host response in our lovely human urothelial microtissue model! Great collaboration with @gpollara.bsky.social & @scottishwormboy.bsky.social #UTISky #UTI Join us! www.ucl.ac.uk/work-at-ucl/...
Interested in T cell immunity in TB? Check out our new pre-print on antigen-agnostic identification of generalisable human in vivo Mtb-reactive T cell responses: www.biorxiv.org/content/10.1... with @qimmuno.bsky.social & @innate2adaptive.bsky.social
Evolution of T cell responses in the tuberculin skin test reveals generalisable Mtb-reactive T cell metaclones.
T cells contribute to immune protection and pathogenesis in tuberculosis, but measurements of polyclonal responses have failed to resolve correlates of outcome. We report the first temporal…
biorxiv.org
Dr Munyaradzi Musvosvi speaks about the Titan Vaccine Research Project which will allow selection of most promising TB vaccine candidates. This work is supported by the South African mRNA Vaccine Consortium & funded by @samrcza.bsky.social @tomscriba.bsky.social www.youtube.com/watch?v=zwPM...
Immunopathology of TB: SATVI researchers discuss a groundbreaking study which investigates the role of lymph nodes in the context of mycobacterium tuberculosis infection and disease. The study was funded by a grant from @wellcomeleap.bsky.social a program of youtu.be/8_gCOAfWUpw
Immunopathology of TB: Studying the role of the lymph nodes in the TB spectrum.
YouTube video by SATVIUCT
youtu.be
2 weeks to the deadline for applications to this post.. take a look, get in touch if you want hear more, don't hold back😎
Mahdad Noursadeghi@mnoursad.bsky.social · last yr.We’re hiring! Looking for a laboratory post-doc fellow to help us disentangle protective and pathogenic T cells in TB, so we can stratify disease-risk after infection, and develop more effective vaccines. Interdisciplinary science in the heart of London. What's not to like? More here: bit.ly/4iIEiwu
It's just under 1 month to World Immunisation Week 2025 (24th - 30th April)! Check the link below to read more about this crucial campaign for global health. www.who.int/campaigns/wo... #WorldImmunisationWeek #VaccinesWork #WHO
World Immunization Week 2025
World Immunization Week, celebrated in the last week of April, aims to promote the life-saving power of immunization to protect people of all ages against vaccine-preventable diseases. Vaccines are on...
who.int
Academic Clinical Lecturer Posts in Infection now out: for people training in ID in UK & hold/imminently completing PhD. 2 posts @lshtm.bsky.social shorturl.at/EIUIz 1 at St Georges & 1 at Kings shorturl.at/8kDY3 If interested in @lshtm.bsky.social posts get in touch. UK ID people please share!!
We’re hiring! Looking for a laboratory post-doc fellow to help us disentangle protective and pathogenic T cells in TB, so we can stratify disease-risk after infection, and develop more effective vaccines. Interdisciplinary science in the heart of London. What's not to like? More here: bit.ly/4iIEiwu
This is a great initiative!
Georgia Walton@drgeorgiawalton.bsky.social · last yr.I am beyond excited to share that you can now apply to observe a @wellcometrust.bsky.social #DiscoveryResearch shortlisting Committee! If you plan to apply to us in the next 2 years, apply to be an Observer now to better understand what happens once you click submit! wellcome.org/grant-fundin...
Best #Nikolaus 🎅! Our paper on how the 🫁 microenvironment can shape #innate immunity against #viruses is out @sciimmunology.bsky.social This was a herculean effort brilliantly led by @pauljbaker.bsky.social who singlehandedly established the model in the lab during the pandemic. 🧪 #Immunosky 1/9
Cool illustration how informative human challenge models can be! Here #SARSCoV2 challenge model has identified: 👉 insights into differential regulation of IFN-stimulated genes 👉 potential diagnostic biomarkers for early (MX1) & late (IFI27) viral infections #IDSky #ImmunoSky #COVID19 #MedSky 🧪
Mahdad Noursadeghi@mnoursad.bsky.social · 2y agoAlso out now.. after peer review, our analysis of blood transcriptional biomarkers of acute respiratory viral infection leveraging the SARS-CoV-2 human challenge model: www.nature.com/articles/s41...
Also out now.. after peer review, our analysis of blood transcriptional biomarkers of acute respiratory viral infection leveraging the SARS-CoV-2 human challenge model: www.nature.com/articles/s41...
SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections - Nature Communications
It’s not always clear whether blood biomarkers are differentially expressed in the time course of viral infections. In this SARS-CoV-2 human challenge study, the authors identify distinct single-gene ...
nature.com
Reposting for anyone who hasn't clocked this paper yet- fab analysis by @gushamilton.bsky.social @gpollara.bsky.social and team - persuaded anti-IL6 unlikely to increase TB risk , and now need to test it's potential as therapeutic to reduce immunopath. What else can we infer about TB immunology?
Gabriele Pollara@gpollara.bsky.social · 2y ago🚨 Delighted to share our paper defining a new role for IL-6 in TB. 🚨 We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB. Lead author @gushamilton.bsky.social #TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan... Thread 👇 (1/8)
exciting.. congratulations @gpollara.bsky.social @jennyrohn.bsky.social - look forward to hearing more about it
Gabriele Pollara@gpollara.bsky.social · 2y agoThis has been a great project to devise and put together, integrating cutting-edge lab models, bioinformatic analyses and clinical samples. It's now going to be even more fun working with @jennyrohn.bsky.social and @scottishwormboy.bsky.social over the next few years on it! 🎊 #UTISky