Blacksky. Available now on iOS and Android.

Blacksky Algorithms@blackskyweb.xyz · last wk.

Joining the beta is easy. Download for iOS: testflight.apple.com/join/ST8N2Qda Download for Android: play.google.com/store/apps/d... If you run into any issues, you can follow the instructions here for help: docs.blacksky.community/info-about-b...

🚨 New today in Nature 🦟 After decades of debate, we show that climate change has probably made malaria worse in sub-Saharan Africa, causing about 1 extra case per 1,000 children. But: malaria eradication efforts have pulled the other direction 200 times harder. 🔓 www.nature.com/articles/s41...

#lipidtime

André Nadler@nadlerlab.bsky.social · last wk.

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

Nature research paper: Brown bullhead catfish melanoma represents a novel transmissible cancer go.nature.com/4fh8bF8

Brown bullhead catfish melanoma represents a novel transmissible cancer - Nature

Whole-genome sequencing analysis of tumour and matched non-tumour host tissues of the brown bullhead catfish reveals a type of naturally occurring transmissible cancer.

go.nature.com

We are hiring @umichmicroimmuno.bsky.social ! Tenure-track assistant professor position in our Microbiology and Immunology department. We are especially looking for someone working in bacterial pathogenesis

🚨🚨 Faculty search! Spread the word! 🚨🚨 The Pathology, Microbiology, and Immunology Department at Vanderbilt is hiring! Special consideration will be given to faculty working with Risk Group 3 pathogens (so you can join us in our brand new state-of-the-art BSL3!) apply.interfolio.com/188545

The Mamedov Lab is hiring a Postdoctoral Fellow to apply CRISPR screening and functional genomics to a long-standing mystery in cancer immunology with high translational potential: how do human γδ T cells recognize stressed and cancerous cells? #gdTcells www.nature.com/naturecareer...

Post-Doctoral Fellow – Mamedov Lab - Philadelphia, Pennsylvania (US) job with The Wistar Institute | 12860872

The laboratory of Dr. Murad Mamedov at The Wistar Institute is recruiting a Postdoctoral Fellow.

nature.com

Using fiber photometry, mesoscopic imaging, and two-photon microscopy, we simultaneously monitored ACh together with DA, 5-HT, NE, and calcium signals with high spatiotemporal resolution. www.nature.com/articles/s41... (3/3)

Red-shifted GRAB acetylcholine sensors for multiplex imaging in vivo - Nature Neuroscience

The authors develop red fluorescent GRAB acetylcholine (ACh) sensors and highlight rACh1h as a robust tool for multiplex recording together with various green sensors. Using fiber photometry, mesoscop...

nature.com

Poverty is a major driver of TB.Conditional cash transfers combined with counselling improve pre-treatment loss to follow-up.In this economic analysis our modelling projections show that this intervention is cost-effective and can reduce incidence and mortality. www.sciencedirect.com/science/arti...

Cost-effectiveness of conditional cash transfers with pre- and post-test tuberculosis counselling in South Africa: a modelling analysis

Tuberculosis (TB) disproportionately affects low-income populations due to socioeconomic barriers. Conditional cash transfers (CCTs) are promising str…

sciencedirect.com

ICYMI: Reporting on 2 unrelated patients with a rare inborn error affecting CD48: doi.org/10.1172/JCI1... Milanesi et al. characterize the variants in humans & mice, revealing the importance of CD48 in regulating T-cell responses during infections & in the prevention of excessive inflammation

CASP5c “the movie” is now playing in the April 30th 2026 issue of @nature.com www.nature.com/articles/s41...

Beautifully done and important trial. An effective mTb test that utilizes tongue swab specimens will be absolutely transformative for Tb diagnosis especially is resource limited settings. Definitely practice modifying. www.nejm.org/doi/full/10....

Pulmonary Tuberculosis Detection with MiniDock MTB Using Swab Samples | NEJM

Improved diagnostic tools for tuberculosis that are suitable for use in peripheral health centers are essential for reducing the persistent gap between estimated and notified cases. The diagnostic ...

nejm.org

So we blocked IFNγ in Mtb infected macaques and….the animals were fine. Turns out mice overestimate the importance of IFNγ in TB because IFNγ drives iNOS in mice but not macaques or humans. This means we don’t actually know how T cells suppress Mtb. rdcu.be/ff9GB #tuberculosis #immunology

My award for best stealth philosophical commentary on biology of the last few months goes to @lozanzi.bsky.social & Boehmer's use of quotes: 'Additionally, even one ‘‘cell type’’ can have a different PRR repertoire depending on its anatomic distribution within an organ or the age of the host'

Interferons in health and disease

The cytokine messenger proteins known as interferons are central to protective immune responses against infections, but they are also involved in inflammatory and autoimmune diseases. This review maps...

cell.com

Very grateful to receive the Deutscher Krebspreis 2026 (Experimental Cancer Research) together with Marcus Conrad. This recognition reflects the incredible efforts of our teams and collaborators over the years @uni-wuerzburg.de

Defensive lipid droplets are PUFA reservoirs driving bacterial clearance and inflammation https://www.biorxiv.org/content/10.64898/2026.03.12.711356v1

I'd like to see this problem analysed at the single cell multi-omics level 'Advances in research technolo- gies are crucial for the scientific enterprise but have an unintended consequence: when pow- erful techniques become widely available, they tend to be applied without a good question in mind.'

On the balance of knowledge - Nature Reviews Immunology

Ruslan Medzhitov shares his thoughts on the balance between generating data and developing theories in immunology, with a focus on exploring the rules that govern complex systems.

nature.com

Many of you in the mycobacterial community attended the awesome inaugural 2025 Biology of Mycobacteria GRC, organized by @heran.bsky.social and myself: www.grc.org/biology-of-m.... I am writing with an update about this conference as the new chair.

In this new paper by @nelson-lab.bsky.social, we found that pre-exposure of NHP to glucocorticoids impairs control of SARS-CoV-2 and is associated with reduced pDC, eosinophil and γδT cell responses. journals.plos.org/plosone/arti...

Glucocorticoids suppress early lung inflammation and impair control of SARS-CoV-2 in non-human primates

In severe cases of COVID-19, glucocorticoid treatment improves clinical outcomes. However, in non-hospitalized patients, glucocorticoids have limited benefit and may impair viral clearance. Here, we u...

journals.plos.org

Harnessing mucosal immunity for protective vaccines www.nature.com/articles/s41...

Harnessing mucosal immunity for protective vaccines - Nature Reviews Immunology

Many clinically relevant pathogens enter the body through mucosal surfaces, yet conventional parenteral immunization is insufficient to elicit robust mucosal immunity. This Review examines the unique ...

nature.com

Do you work with the Aspergillus fumigatus model isolates Af293 or CEA10? If so, we want to collaborate with you! In return for your lab's participation we will sequence your strain for free and provide co-authorship on the final paper. Learn more here: asp-fumi-seq-project-2025.vercel.app

📢2nd Annual Meeting of the EFIS-IL Sex Differences in Immunity Study Group! 🗓️October 8-9, 2026 📍Hamburg, Germany 🔗https://linktr.ee/EFIS_ISD @yefis-immunology.bsky.social @dgfi-org.bsky.social @sfi-immunologie.bsky.social @swimm-immuno.bsky.social @irishimmunology.bsky.social @finnsocimm.bsky.social

Immune Sex Differences@sexdiffimmunity.bsky.social · 6mo ago

Our second annual meeting - please save the date and distribute

Help me welcome our latest Plague Dr.! Congratulations to Dr. Sheneman on successfully defending her PhD on Friday the 13th 🎉🍾!

'Tumours boost their own growth by attracting & commandeering nearby sensory nerves (...) By ‘plugging into’ tumour cells, these nerves can send a signal to the brain that subdues the protective activity of immune cells at the tumour site — allowing the cancerous cells to proliferate unchecked'

How tumours trick the brain into shutting down cancer-fighting cells

Lung cancer in mice hijacks neurons to send a signal that subdues the immune system, study finds.

nature.com

Not something you see in textbooks very often: tripolar mitosis.

A ‘simple’ experiment but an amazing gem of a reference! Just stimulate blood, observe and describe… #ImmunoSky

Adam Braithwaite@braithwaiteat.bsky.social · last yr.

Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data 🧪 doi.org/10.1101/2025...

Please share and distribute ILC6 in Vancouver Abstract submission and registration are open: ilc6vancouver.com #immunosky #ILC6vancouver #ILC6 Lots of presenter spots available Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.

This is a very appealing meeting in Paris later this year... "The complexity of mycobacterial infections: from research to real-world impact" #EMBOComplexInfections #TBSky for the tuberculosis research, but also #NTM #Leprosy #IDSky #ImmunoSky meetings.embo.org/event/26-myc...

Important paper by Björn Corleis. For decades a central tenet of #tuberculosis immunology has that IFNγ-driven iNOS expression in macrophages is the primary mechanism of bacterial control. Turns out this is really only in mice and maybe cattle. It’s not true in most species including humans an NHP.

bioRxiv Immunology@biorxiv-immuno.bsky.social · 7mo ago

Species-specific iNOS expression distinguishes epithelial and myeloid IFNγ responses in tuberculosis https://www.biorxiv.org/content/10.64898/2026.01.11.697682v1

The Barber lab is looking to hire post-docs to work on #tuberculosis #immunology using murine and NHP models. BSL3 experience not required. Check out our lab in the NIH intramural program in Bethesda MD!