Micha Sam Brickman Raredon

@msbr89.bsky.social

Scientist/Engineer. Assistant Professor @ Yale School of Medicine. Tissue Biology, Lung Regeneration, Data Science. Here to learn! RaredonLab.com & GitHub.com/RaredonLab

This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...

Basement membrane turnover controls cell shape

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...

cell.com

The legendary "walking bed" page from Winsor McCay's "Little Nemo in Slumberland" was published on July 26, 1908. If there’s a Mt. Rushmore for Sunday pages, this one is certainly on it.

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There's not much I can say about Alan Turing's cryptography in WWII that Benadryl Cabbagepatch didn't already cover in "Imitation Game." But did you know he explained how the tiger got its stripes, why hair parts on one side & why your heart tilts to the left? Let's talk about Turing patterns.

The Imitation Game, based on the true story of Alan Turing and the Enigma code.

This video shows wave patterns in the cell's cortex, the layer just below the outer membrane where so much signaling occurs. These waves are a self-organizing pattern that prepares an oocyte for polar body emission & cytokinesis during meiosis, using simple rules that produce complexity from chaos.

Journal of Cell Biology@jcb.org · 2w ago

Michaud, @andrewgoryachev.bsky.social, von Dassow, @xenresearchcenter.bsky.social et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, & RGA-3/4 rupress.org/jcb/article/... 📕 In "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...

AI has made it easy to construct the form of an academic paper without any true insight, and that’s not going away. We might have to move from peer review to peer recommendation. All papers get uploaded to a server, w/ an overlay where experts point to the good ones. The rest can just be ignored.

Ben Williamson@benpatrickwill.bsky.social · 3w ago

The anatomy of an AI-supported academic article is becoming more apparent. I desk reviewed ~70 manuscripts this week for our journal. Reckon 20ish had significant AI assistance. On top of hundreds of others recently I'm starting to see patterns. Are other editors are seeing the same or similar? 1/

How mammals get their fur? New research from the Milinkovitch-Tzika lab, published in PNAS, shows that chemotaxis—cells moving toward chemical cues—drives hair follicle precursor self-organization during embryonic development, generating diverse fur patterns across mammals. doi.org/10.1073/pnas...

Chemotactic self-organization captures the dynamics of mammalian hair follicle patterning | PNAS

The spatial patterning of mammalian hair follicle precursors in embryonic skin is most commonly studied in the laboratory mouse (Mus musculus), whe...

doi.org