Entryism

AI entryism subverts anti AI critique.

olivia.science

AI in scientific publishing: Slower, worse, and more expensive

There’s a saying in the management world, popularized by NASA administrator Daniel Goldin in the 1990s, that the goal of technological improvements is to make products faster, better, and cheaper. Alt...

science.org

Editorial and peer review dynamics at elite general science journals

Analyses of deidentified data reveal complex interactions that quantify success at elite general science journals.

science.org

3-Hydroxykynurenine targets kainate receptors to promote defense against infection - Nature Chemical Biology

A tryptophan metabolite was identified that acts systemically to promote defense against bacterial infection by targeting kainate receptors (KARs), revealing a novel intersection between tryptophan me...

nature.com

Optogenetic mediated contractility enables reversible control of microglial morphology and migration in vivo

Biermeier et al. use live imaging in zebrafish to show that microglia alternate between distinct morphological states that support brain surveillance and phagocytosis. By optogenetically controlling cytoskeletal contractility, they demonstrate programmable, reversible control of microglial behavior in the living brain.

dlvr.it

Zebrafish macrophages convert physical wound signals into rapid vascular permeabilization - Nature Communications

Real-time imaging in zebrafish shows that macrophages convert fast osmotic wound signals into rapid vessel permeabilization via cPla2-dependent nuclear membrane mechanotransduction.

nature.com

IL-22 from enteroendocrine cells promotes early-life gut motility in zebrafish through the microbiota

The gut microbiota, immune system, and enteric nervous system interact to regulate adult gut physiology. However, the mechanisms establishing gut physiology during development remain unknown. We repor...

science.org

Cellular and molecular mechanisms of skin wound healing - Nature Reviews Molecular Cell Biology

This Review discusses the complex mechanisms of wound healing — cell migration, matrix remodelling, inflammation and angiogenesis — and the contributions of different cell types, including immune cell...

nature.com

Aged Zebrafish as a Spontaneous Model of Cardiac Valvular Disease

Natural ageing in zebrafish results in spontaneous development of valvular degeneration in both the atrioventricular (AV) and bulboventricular (BV) valves. Aged zebrafish valves are larger and exhibi...

onlinelibrary.wiley.com

A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing

Promoting intestinal regeneration and enhancing mucosal healing have emerged as promising therapeutic alternatives for treating intestinal disorders t…

sciencedirect.com

Why Causal Knowledge Is Pragmatically Possible: Bridging Philosophical Skepticism and Scientific…

When we observe the world, we note that events consistently follow one another. As David Hume famously argued in An Enquiry Concerning…

medium.com

Distinct T-cell receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus

The foetal thymic T-cell receptor (TCR) repertoire is distinct from adult, and it is less governed by MHC-restriction, more closely encoded by genomic sequence with distinct gene-segment usage includi...

doi.org

BSDB - The Fascinating World of Developmental Biology (full length)

YouTube video by The Company of Biologists

youtu.be

Discrimination between disciplines

Scientists working in fields with a high proportion of women researchers receive lower scores during evaluation and are less likely to get funded, suggests new study.

elifesciences.org

Emerging blood and immune cells

Live imaging of zebrafish embryos reveals early differences in the genesis of the cells that become blood and immune cells, shedding light on how these precursors emerge from vessels.

elifesciences.org

A tryptophan metabolite modulates the host response to bacterial infection via kainate receptors

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

biorxiv.org