@pgrivasmdphd.bsky.social
1/ Best practices for 2L+ tx #MetastaticUrothelialCarcinoma 🧵 w🌟 @tiansterzhangmd.bsky.social & me ...assuming EV+P 1L ✅FGFR3 alts: THOR/erda 🎯Trop-2: sacituzumab govitecan 🏁HER2 IHC 3+: T-DXd Support by edu grants: Astellas, Gilead Sci, Merck, Seagen #CME from @bonumce.bsky.social ℹ️👇
This GU oncology family — wonderful first #AUC3 consensus conference! @drchoueiri.bsky.social @pgrivasmdphd.bsky.social @davidaggen.bsky.social
Expanded indication for TDXd!
The ASCO Post@ascopost.bsky.social · 2y agoThe FDA has approved trastuzumab deruxtecan (T-DXd) for patients with HR-positive, HER2-low, or HER2-ultralow metastatic breast cancer based on DESTINY-Breast06 trial results. #BreastCancer #Oncology ascopost.com/news/january...
Awesome panel moderated by #MontyPal #BradMcGregor for non clear cell #Kidneycancer. Histology matters! And so do molecular markers! #AUC3 @drchoueiri.bsky.social @pgrivasmdphd.bsky.social @davidaggen.bsky.social @erplimackmd.bsky.social
Redefining first-line options for advanced urothelial carcinoma! Insights on platinum chemotherapy, immunotherapy combos, and patient-tailored strategies. @tiansterzhangmd.bsky.social @oncoalert.bsky.social @oncbrothers.bsky.social #Oncology #BladderCancer
Huge kudos to the NCCN for officially incorporating prostate cancer into the Genetic/Familial High-Risk Assessment Guidelines. We've come a long way!
This Christmas and every year I remember my current and past patients with ornaments on our tree. Have been fortunate to care for thousands in my ten year career in oncology. Hope to help thousands more in the years to come. 🎄🕯️
Launching #AUC3 in Miami, consensus across kidney and bladder cancers. From small steps to significant scientific advances that change our patients’ lives. @drchoueiri.bsky.social #MontyPal #RanaMcKay #JonathanRosenberg
#BrianShuch kicks us off, local #kidneycancer heterogeneous - guppies, goldfish and sharks! Integrating staging & biomarkers to help us evaluate risk and prognosis. #AUC3
Drs. #NaomiHaas #HansHammers debate locally advanced #kidneycancer and use of periop immunotherapy. Grading, staging, and prediction of risk/benefit leads to rigorous shared decision making with our patients. @drchoueiri.bsky.social #AUC3
#BrianRini & #MikeAtkins debate refractory #kidneycancer management after IO front line or adjuvant PD1 inhibitor. Do we rechallenge? Yes likely after a certain time point (6 vs 12 months debated). #AUC3
Great milestone 🎯🥇 for #mCRC treatment #GIonc #OncSky based on the last update clinicaltrials.gov/study/NCT046... FDA grants Accelerated Approval to Encorafenib Plus Cetuximab and Chemo for BRAF V600E+ Metastatic Colorectal Cancer www.fda.gov/drugs/resour...
ClinicalTrials.gov
clinicaltrials.gov
🔍 Does AI reduce #clinician workload? @NEJM study on @NuanceDragon DAX Copilot, an AI-powered documentation tool, found minimal impact on EHR efficiency & financial metrics❗️ 💡AI tools need to be developed in comjuction with 🩺🥼🧑⚕️ not in silos #AIinMedicine #LLMs @oncoalert.bsky.social
Congratulations @n8pennell.bsky.social and all elected members @ascocancer.bsky.social
Jame Abraham, MD, FACP@jameabraham.bsky.social · 2y agoCongratulations to @n8pennell.bsky.social @clevelandclinic.bsky.social for being elected to the @ascocancer.bsky.social board of Directors! @oncoalert.bsky.social so proud my colleague!
“Why are we listening to men & not women?” asks Dr @narjustflorezmd.bsky.social of @florezlab.bsky.social This question & the increase in #lungcancer diagnoses among younger women vs men are the genesis for the #HearHer campaign. Read more & help us change this👇 healio.com/news/hematolog… #LCSM
Interesting article studying oncologist’s decision-making from a psychosocial perspective: #Oncologists exposed to scenarios of a “nice” or “demanding” pt were associated with less recommendations of chemotherapy near the #EOL . #heme/onc #lcsm #lcam #oncsky #medsky doi.org/10.1093/onco...
Patients’ psychosocial attributes and aggressiveness of cancer treatments near the end of life
AbstractBackground. While the use of chemotherapy near the end of life (EOL) has been identified as a relevant criterion for assessing quality of cancer ca
doi.org
Key takeaways: •The #HearHer campaign focuses on gender disparities in lung cancer diagnosis and clinical trial enrollment. •Clinicians should take women’s concerns seriously and make use of imaging for early detection. Article here: www.healio.com/news/hematol...
🧵 Real world effectiveness study using #EHR from 20 health systems: #COVID19 vaccination ⬇️ risk of #longCOVID in kids/adolescents during Delta & Omicron waves. Mediation analysis suggests effectiveness is indirect, via ⬇️ the risk of #SARSCoV2 infection. #MedTwitter #MedSky
Link to the original study examining real world effectiveness of #COVID19 vaccination in reducing risk of #LongCovid in kids & adolescents here: www.thelancet.com/action/showP.... #MedSky #IDSky #Pediatrics #GetVaccinated
thelancet.com
Stayed active during 17-hour flight from SEA->Singapore :-) Looking forward to present TROPiCS04 phase 3 trial data at #ESMOASIA on Dec 7 ~10am local time discussed by Dr. Friedlander @oncoalert.bsky.social @achoud72.bsky.social @erplimackmd.bsky.social @valdesan.bsky.social @fredhutch.bsky.social
Thank you Mirrors of Medicine & dear Colleagues #PROSCA24 #BLADDR24 & #RENALC24 FINAL STATS with OVER 21 million impression on X SHOUT OUT TO Our Ambassadors Specially @drnataliagandur.bsky.social @barbaramelao.bsky.social @pgrivasmdphd.bsky.social @achoud72.bsky.social
As we return from Thanksgiving Holidays we are grateful for everyone’s hard work & @ASCO mission to support providers & patients! Would like to remind active members to participate in @ASCO election-stellar candidates across all categories-Deadline: Dec 3rd 3pm EST society.asco.org/about-asco/a...
ASCO Election
ASCO Election
society.asco.org
“The effectiveness of telehealth in delivering psychosocial, nutritional, and physical activity support highlights its potential to improve patient outcomes and overcome barriers to care” @pallonccop.bsky.social #oncsky ascopubs.org/doi/10.1200/...
Enhancing Cancer Supportive Care: Integrating Psychosocial Support, Nutrition, and Physical Activity Using Telehealth Solutions | JCO Global Oncology
This review explores current guidelines for integrating psychosocial support, nutrition, and physical activity into cancer care and examines the resources available to deliver comprehensive care effec...
ascopubs.org
#PROSCA24 ✨PSMA is the imaging choice in BCR ✨impact on clinical management ~60% ✨PPV 85-90% ✨different PSMA tracers with different detection rate ✨PROMISE registry to build monogram to predict survival: in BCR setting the nomogram had a strong correlation with survival ‼️for MDT: use PSMA11
The OncoAlert Network 🚨@oncoalert.bsky.social · 2y agoDay One of #PROSCA24 Presenter: Dr Karolien Goffin Biochemical recurrence following ocal therapy PSMA-PET in BCR – what to expect? @drnataliagandur.bsky.social @barbaramelao.bsky.social @yukselurun.bsky.social @achoud72.bsky.social
Impact of cycle 1 irAEs on ICI outcomes: - 683pts from SWOG DART trial - g1-2 irAEs = ⬆️OS HR 0.61 p < 0.001 - g3+ irAEs = ⬇️OS HR 1.41 p= .025 - g1-2 derm irAE = ⬆️OS v other g1-2 irAE HR 0.67 p=0.002 Congrats @eladsharonmd.bsky.social @oncoalert.bsky.social academic.oup.com/jnci/advance...
First Cycle Toxicity and Survival in Patients with Rare Cancers Treated with Checkpoint Inhibitors
AbstractBackground. Associations between immune-related adverse events (irAEs) from checkpoint inhibitor therapy and outcomes have been previously evaluate
academic.oup.com
Do systemic responses to ICI (eg irAEs) associate w outcomes? Nice use of existing basket studies by @pateloncology.bsky.social @eladsharonmd.bsky.social Razelle Kurzrock et al
Jarushka Naidoo@drjnaidoo.bsky.social · 2y agoImpact of cycle 1 irAEs on ICI outcomes: - 683pts from SWOG DART trial - g1-2 irAEs = ⬆️OS HR 0.61 p < 0.001 - g3+ irAEs = ⬇️OS HR 1.41 p= .025 - g1-2 derm irAE = ⬆️OS v other g1-2 irAE HR 0.67 p=0.002 Congrats @eladsharonmd.bsky.social @oncoalert.bsky.social academic.oup.com/jnci/advance...
Thank you Mirrors of Medicine & dear Colleagues #PROSCA24 #BLADDR24 & #RENALC24 have just concluded with OVER 20 million impression on X SHOUT OUT TO Our Ambassadors Specially @drnataliagandur.bsky.social @barbaramelao.bsky.social @pgrivasmdphd.bsky.social @achoud72.bsky.social
