@sbcf.bsky.social can we have the link? 😇

This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...

Basement membrane turnover controls cell shape

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...

cell.com

Watch a muscle fiber take shape. 🔬 This microscopic video captures a muscle cell fusing with a developing muscle fiber, with cell membranes visible in purple and yellow. The Rando Lab uses live-cell imaging to understand how cells coordinate muscle regeneration. Credit: Tamas Nagy/Rando Lab

📢 JOB ALERT! 📢 I am recruiting a 30-month postdoc to work on modelling the vision of trilobites @hfspo.bsky.social ! If you like 3D data, fossils, and functional morphology, this is the one for you! 📆Deadline 27. Aug Pls contact me with any Qs and share widely! www.bristol.ac.uk/jobs/find/de...

Decades ago in 🇨🇱 cellbio meeting immunologist delivers a ppt with 90% immuno and 10% cellbio. Everyone baffled. 1st row sitting senior PI rise the hand: -why did you come to this cellbio meeting? -yeah I wonder the same sometimes (laughs nervously) -I'm not joking, why?! This 👇🏽 is magnificent too

Richard Sever@richardsever.bsky.social · last wk.

Speaker refused to divulge the name of compound X in Q&A after his ASCB talk. Questioner [who will be known to many cell biologists] blew a raspberry into the mic and gave the speaker the finger.

This afternoon's imaging lab at #IALSJanelia is all about subcellular structures, highlighted here by myosin (white) and actin (orange). These membrane ruffles were captured on our lattice light-sheet microscope by @cmhobson.bsky.social

Our work on Trichoplax locomotion and mechanosensing capabilities is out now in @currentbiology.bsky.social. Congrats Marvin Leria & all co-authors! authors.elsevier.com/c/1n8Ig3QW8S...

Michaud, @andrewgoryachev.bsky.social, von Dassow, @xenresearchcenter.bsky.social et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, & RGA-3/4 rupress.org/jcb/article/... 📕 In "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...

This is not AI. This is real microscopy! 🔬 An intact gut, rendered transparent and imaged in 3D using light-sheet microscopy! 🤓 Looking inside organs to investigate where pathogens, immune cells, or disease processes may persist. More at: www.nature.com/articles/s41... Happy #FluorescenceFriday!

Microscopy beautifully reveals the dynamic nature of biology but quantifying that motion can be tricky! In the latest paper from @aicjanelia.bsky.social, out now in @jcellsci.bsky.social, we present a tool for measuring amorphous motion: OpticalFlow3D journals.biologists.com/jcs/article/... (1/7)

OpticalFlow3D – a tool for measuring amorphous motion in three-dimensional fluorescence microscopy images

Summary: Biological motion can be difficult to define and measure. Optical flow is uniquely suited to this challenge. We provide tools for 3D optical flow and illustrate its use in extracting biologic...

journals.biologists.com

What does frontier science look like? 🧪 At #HFSPmtg2026, it spans everything from cell migration and photosynthesis to evolution, plant biology or ocean microbiomes. Different questions. Different approaches. One community exchanging ideas across disciplines! 💪 #HFSP #sts

Another #FluorescenceFriday. When the world is going crazy, I find some peace watching at these myeloid cells (🔴) going about their day. They exist in tissue surrounded by other cells (🔵), and you can see them popping up and down, going in and out of plane as they explore their surrounding.

Bringing together science & art, @manuelthery.bsky.social & the CytoMorpho lab describe their project on how cells adapt their shape to their environment using the Musée d’Orsay as their template! The full performance was presented over two nights at the museum earlier this year. #sciart #cellbio

Living Architectures - FocalPlane

Living Architectures - Case studies

focalplane.biologists.com

Bile acid retention in efferocytic #macrophages shapes their inflammatory status during #cholangitis. New study from Amirah Al Jawazneh, Imke Liebold, Stephanie Leyk, Lidia Bosurgi (Universitätsklinikum Hamburg Eppendorf) et al.: rupress.org/jem/article/... @pjsaez.bsky.social #inflammation

I wanted to like QED's new 1% preprint ranking. I really did. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review. open.substack.com/pub/blekhman...

My Peer Review of The 1%

I wanted to like QED's new 1% ranking. I don't.

open.substack.com

I know for a fact that this list is 100% human-generated! For that reason, there are almost certainly some excellent research that I've missed.... Drop me a message if you have any suggestions that I should add to the list.

FocalPlane @focalplane.bsky.social · last mo.

📢Check out our latest preprint list on FocalPlane In this list, we focus on the latest tools and techniques in imaging, including sample prep, probes, hardware and software. focalplane.biologists.com/2026/06/26/m... Let us know if you've been reading a preprint that we should add to our list.

Applications are open for the international course “Developmental Biology” organized by the Institut Curie in partnership with @sorbonne-universite.fr 📅 Oct. 19–28, 2026 (Paris) ⏳ Jul. 19 & Sept. 18 🔗 training.institut-curie.org/courses/developmental-biology-2026

Sometimes I just like looking back at my old data and see if I'd spot something I've missed. And more often than not, I become more appreciative of the result. Here is a wound healing assay of transformed melanocytes from 10yrs ago. They do look like neurons! not quite #fluorescencefriday but cool!

Every few minutes, a dragonfly dives into water and takes off again, turning several forward somersaults as it ascends. The purpose of the behavior? The quick dip cools the insect down, and the loop-the-loops help it dry off by flicking away the water. https://scim.ag/3Vw2Df1 #InsectWeek

Al Jawazneh, Liebold, Leyk, Bosurgi et al. show that engulfment of bile acid–loaded hepatic parenchymal cells results in the transfer of bile acids to phagocytic #macrophages, altering their inflammatory profile. rupress.org/jem/article/... @pjsaez.bsky.social #Inflammation #Cholangitis

8 hours. That’s all fish need to heal wounds 🐟⏱️ Why are they so fast compared to humans? I break down the science of rapid regeneration in a microscopy story 🔬 Watch here: youtu.be/Mt9f61adaP0 #FluorescenceFriday #Microscopy

Our image competition with #ELMI2026 could hardly be closer with just 3 votes separating the top 2 images, with three others close behind. If you haven’t voted yet, you have until 23:59 BST tonight (18 June) to register your vote! focalplane.biologists.com/2026/06/08/f...

FocalPlane x ELMI2026 image competition: vote for your favourite - FocalPlane

FocalPlane x ELMI2026 image competition: vote for your favourite - News

focalplane.biologists.com

The array of organs in the animal body differ dramatically in their architecture, but cell-cell adhesion mediated by cadherins is a common principle. Our lab usually focuses on epithelia but cadherins are also active in migrating mesenchymal cells like these migrating testis myoblasts 1/n 🧪

Join us to hear Maike Frye at #Angioscience26! Maike studies how extracellular and physical microenvironments govern vessel integrity, notably demonstrating how matrix stiffness instructs lymphatic vessel formation. Deadline June 15th. Register today!

We kicked off today the 1st session of the Focal Plane #CellMigration webinars Brilliant talks by @juanmagararc.bsky.social , @kyohalie.bsky.social & @djcohen.bsky.social Tks to Helen @focalplane.bsky.social for organization & support. Looking FWD to the next one @valeriaventurini.bsky.social !

Pablo J. Sáez@pjsaez.bsky.social · 2mo ago

1 week to start🔥 New @focalplane.bsky.social webinar series focused on #CellMigration, register & join us▶️, it will be fun! pls spread the word, in the next one, ECRs could apply to show their work ;) ▶️ to register: focalplane.biologists.com/2026/05/29/n... @dgz.bsky.social @the-node.bsky.social

Cellular structure self-organizes through an interplay between internal mechanisms and external cues. The single-celled suctorian P. collini builds a trap structure to capture large prey using microtubule feeding tentacles, creating feedback between cell morphology and prey availability.

The first webinar in our #FocalPlaneFeatures #CellMigration webinar series is tomorrow (Thursday 11 June) at 15:00 BST (UTC+1). Join us via Zoom to hear from @juanmagararc.bsky.social, @kyohalie.bsky.social & @djcohen.bsky.social. focalplane.biologists.com/2026/05/29/n...

Seeking a post-doc for the LaJoie lab at the Human Technopole, Milan, Italy! We are looking for candidates from the fields of biochemistry, cell biology, and proteomics, who are interested in studying protein interactions of the nucleus 🤓 lnkd.in/dTG2CgXF

We are thrilled to announce our new preprint from the wonderful @sorayavillaseca.bsky.social Ever wondered how cells squeeze through tiny spaces in embryos? Neural crest cells use Dynein to transport their nucleus along microtubules. Check out the preprint!! www.biorxiv.org/content/10.6...

1 week to start🔥 New @focalplane.bsky.social webinar series focused on #CellMigration, register & join us▶️, it will be fun! pls spread the word, in the next one, ECRs could apply to show their work ;) ▶️ to register: focalplane.biologists.com/2026/05/29/n... @dgz.bsky.social @the-node.bsky.social