Explore how Expansion-dSTORM resolves unresolvable cellular structures in our new papers: • 8-nm microtubule periodicity, clathrin lattices & NUP96 dimers • Presynaptic vesicle docking sites (40-nm Munc13-1/RIM rings) All using unmodified cells & standard immunolabeling: ▶️ rdcu.be/fwBYY
If you are interested in resolving the structure of isolated proteins with ~1 nm resolution using Expansion Localization Microscopy with spontaneously blinking dyes (JF635b), then take a look here: ▶️ pubs.acs.org/cbihbp/artic...
Single-Step Expansion SMLM Enables Molecular-Resolution Imaging in Cells and Isolated Proteins
Abstract. Expansion microscopy (ExM) enables nanoscale fluorescence imaging on standard microscopes, but its combination with single-molecule localization
pubs.acs.org
Excited to share our new preprint! 📄 We introduce cTRP PicoRulers as programmable reference standards for benchmarking sub-10 nm fluorescence microscopy. From dSTORM over DNA-PAINT to Expansion Microscopy - one platform, many applications.🔬 👉Read it here: www.biorxiv.org/content/10.6...
@science.org is looking for a new editor to look after regenerative medicine and neuroscience submissions. Come join us! Check out this Associate or Senior Editor opportunity recruiting.ultipro.com/AME1123ASEM/...
recruiting.ultipro.com
Very grateful to receive the Deutscher Krebspreis 2026 (Experimental Cancer Research) together with Marcus Conrad. This recognition reflects the incredible efforts of our teams and collaborators over the years @uni-wuerzburg.de
Expansion microscopy improves resolution, but integration with SMLM remains challenging. In our new preprint, we present a simplified strategy using spontaneously blinking dyes, validated against well-defined reference structures including NPCs and PicoRulers! ➡️ www.biorxiv.org/content/10.6...
Congratulations Arindam and welcome back to Würzburg!
Arindam Ghosh, PhD@arindam92.bsky.social · 9mo agoHappy to share that I will be starting my independent research career as a Research Group Leader at the German Cancer Research Center (DKFZ). Starting from January 2026, my group will be based at DKFZ National Center for Tumor Diseases (NCT WERA), Würzburg, Germany.
🚨 New Preprint! Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons. ▶️ www.biorxiv.org/content/10.1...
Welcome to the youngSMLMS, a pre-SMLMS event for students, PhDs & PostDocs! We’ll explore science & career in workshops, talks, roundtables, a panel and with time to network. --> Thanks to our sponsors, youngSMLMS is free & we cover accommodation for all presenting their work. Thus, register now!
Fully Funded PhD Scholarship in Centrosome Biology in the lab of Prof Ciaran Morrison: www.findaphd.com/phds/project...
Fully Funded PhD Scholarship in Centrosome Biology at University of Galway on FindAPhD.com
PhD Project - Fully Funded PhD Scholarship in Centrosome Biology at University of Galway, listed on FindAPhD.com
findaphd.com
Look what's happening at the French Embassy in Washington DC.
Chemical Solutions to Structural Biology symposium. Registration and abstract submission now open: isbuc.ku.dk/chemical-sol...
An excellent review about fluorescence labeling strategies by @beliulab.bsky.social Gerti Beliu and colleagues from Würzburg University - highly recommended reading for everybody interested in fluorescence microscopy!
Biophysical Reports@biophysreports.bsky.social · last yr.Online now! Fluorescent labeling strategies for molecular bioimaging. Marcel Streit, Made Budiarta, Marvin Jungblut, and Gerti Beliu. www.cell.com/biophysrepor...
🆕 Our new functionalized docetaxel probe enables superior visualization of dense mitotic spindle structures during cell division by expansion microscopy! ▶️ pubs.acs.org/doi/10.1021/...
Functionalized Docetaxel Probes for Refined Visualization of Mitotic Spindles by Expansion Microscopy
Visualizing the ultrastructure of mitotic spindles, the macromolecular machines that segregate chromosomes during mitosis, by fluorescence imaging remains challenging. Here we introduce an azido- and ...
pubs.acs.org
SAVE THE DATE 👇 #FiNS2025 Frontiers in Neurophotonics Symposium 2025 frontiersneurophotonics.org #Bordeaux, 6-9 Oct 2025 @iins-bordeaux.bsky.social @cnrs.bsky.social @univbordeaux.bsky.social @neurobordeaux.bsky.social @cnrsbiologie.bsky.social @gaellerecher.bsky.social
DChoquet@danielchoquet.bsky.social · last yr.Save the date ! Frontiers in Neurophotonics Symposium 2025 in Bordeaux October 6-9 frontiersneurophotonics.org/2025-speakers/ 🧪
NIH-supported research saves lives: here are two "poster" human beings to prove it. Emily Whitehead: cured of her leukemia by CAR-T developed at Penn. Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.
Delighted to launch our activities on Bluesky with this great news: Our researchers @sauer-lab.bsky.social show in @science.org, how therapeutic #antibodies interact with B cells – thanks to an innovative method of super-resolution microscopy. Congratulations! ➡️ www.uni-wuerzburg.de/en/news-and-...
🔬 Ever wondered how therapeutic antibodies work? 3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies. 📄 Read more: www.science.org/doi/10.1126/...
Super happy to see the manuscript of my former PhD student and close friend Arindam Ghosh, @arindam92.bsky.social, and the Markus Sauer lab, @sauer-lab.bsky.social, being pblished in Science: www.science.org/doi/10.1126/...
Decoding the molecular interplay of CD20 and therapeutic antibodies with fast volumetric nanoscopy
Elucidating the interaction between membrane proteins and antibodies requires whole-cell imaging at high spatiotemporal resolution. Lattice light-sheet (LLS) microscopy offers fast volumetric imaging ...
science.org
Well-deserved Luke
Luke Lavis@rhodamine110.bsky.social · 2y agoGregorio Weber is a giant in our field, and I am deeply honored to receive this award in his name. I want to acknowledge all my collaborators over the years—especially @dyerfulchymist.bsky.social—and the place that made everything possible: @hhmijanelia.bsky.social
Happy to see my MSCA project with @jbneuro.bsky.social lab available on @biorxiv-neursci.bsky.social We Increased network activity in vivo and used dSTORM to look at the nanoscale organization of inhibitory synapses formed onto the AIS and onto tufts dendrites of L2/3 S1 Cortex!
