Zhenjie Wang, Zhe Feng et al. uncover the molecular basis of Ana1-driven #centriole elongation in #Drosophila #spermatogenesis, showing that Ana1/CEP295 promotes longitudinal centriole extension through direct interactions with both Cep135 and #microtubules. rupress.org/jcb/article/...
Paul & Virginie - Centriole Lab
@centriolelab.bsky.social
Virginie Hamel & Paul Guichard Lab at University of Geneva #cryoEM/ET❄️ and #UExM ⚗️ #ExpansionMicroscopy #TeamTomo Genève, Suisse 🇨🇭 https://mocel.unige.ch/research-groups/guichard-hamel/overv
Out now in @science.org Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders | Science www.science.org/doi/10.1126/...
Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders
Lysosomal dysfunction is a well-recognized feature of aging. Here, we used a suite of tools for rapid lysosomal isolation to construct a multitissue atlas of the metabolite changes lysosomes undergo d...
science.org
📣 Abstract submission and early registration are now OPEN for the 7th European Cilia Conference—an official EMBO workshop! 📅 8–12 March 2027 📍 Stresa, Italy Submit and register: meetings.embo.org/event/27-cilia www.eurocilia.eu #EMBOCilia #Cilia2027
We’re accepting abstracts for QBMM, come join an excellent set of speakers, due early Sept
~50% of fertilized eggs arrest during human pre-implantation. Imaging 150+ embryos revealed error-prone 2nd mitotic divisions; centriole overduplication can be suppressed with PLK4 inhibitor. PMID:42276044, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00637-9 #Medsky #Pharmsky 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00637-9
No description available
cell.com
Michaud, @andrewgoryachev.bsky.social, von Dassow, @xenresearchcenter.bsky.social et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, & RGA-3/4 rupress.org/jcb/article/... 📕 In "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...
🔬 #JobAlert Interested in doing a PhD with us in #SyntheticBiology on the Reconstitution of Oscillatory Microtubule-Motor Systems? Check shorturl.at/wis5P (note the eligibility criteria) or/and get in touch with us shorturl.at/WmgOD. Deadline: 31 July 2026 #WeAreHiring #AcademicJobs #ScienceJobs
www.protocols.io/view/cryo-ex... New protocol alert!! Cryo-expansion microscopy of C. elegans and Tardigrades using the high pressure freezer!
Cryo-Expansion Microscopy of C. elegans and Tardigrades
Cryo-Expansion Microscopy of C. elegans and Tardigrades. Expansion microscopy (ExM) improves imaging r. Read full protocol, steps, and materials on protocols.io
protocols.io
From background to foreground: secondary antibodies coupled to lipophilic ATTO dyes enable high-density membrane labeling in super-resolution and expansion microscopy https://www.biorxiv.org/content/10.64898/2026.07.10.737767v1
I am starting my lab at the University of Geneva next January! Incredibly excited to soon be joining the MOCEL department as an Asst. Professor. The lab will use evolutionary cell biology to study chromosomes, centromeres & speciation 🧬🔬🌱 Intrigued, want to join or collaborate? 🔗 helsenlab.org
Helsen lab | chromosome and centromere evolution
The Helsen lab at the University of Geneva explores how centromeres and chromosomes evolve, diversify, and function across eukaryotes. Discover our latest publications, research team, and open positio...
helsenlab.org
How are complex #protein #structures such as #centrioles built? Fortunate to have participated in this study headed by Bryan Tsou’s lab! Rather than self-assembly, #centriole #biogenesis is driven by an inheritable template! 👀 🧵 Thread below👇 Full story: 🔗 doi.org/10.1038/s41467-026-74821-3
Adaptable centriole biogenesis via the intrinsically disordered protein ALMS1 - Nature Communications
Centriole biogenesis is regarded as template-free, variation-free, and genetically determined. Here, the authors describe an adaptable process where inheritance and selection both opera...
nature.com
New preprint 📢 Thrilled to share our long-awaited work on the role of RSX in marsupial X-inactivation. This was a huge team effort over the years, led by @aureliencourtois.bsky.social @sermenchero.bsky.social Sugako Ogushi and Waz Varsally, that allowed us to set up genome editing in opossum embryos
Genome editing of marsupial RSX reveals conserved and divergent principles in mammalian X-inactivation
X-chromosome inactivation balances X-gene dosage between the sexes in eutherians and marsupials. The lncRNA Xist mediates X-inactivation in eutherians but is absent from marsupials. An evolutionarily ...
biorxiv.org
Pyrenoid tubules are essential for supercharging CO₂ fixation, but they're hard to resolve by microscopy. So, we physically expanded cells to see where different proteins go (3 examples below). The central tubule region appears specialized for CO₂ delivery! www.biorxiv.org/content/10.6...
🚨 New in @natmicrobiol.nature.com! We reveal how the antibiotic target PBP1b fortifies the E.coli division site against osmotic rupture. Proud this was completed in our independent labs @dmf-unil.bsky.social, with @avettiger.bsky.social. Congratulations to all authors! 🦠❄️🔬 #teamtomo bit.ly/3SCbOg1 👇
The penicillin-binding protein PBP1b fortifies the Escherichia coli division site against osmotic rupture - Nature Microbiology
A specific isoform of PBP1b functions independently of the activator protein, LpoB, to drive generation of a wedge-like peptidoglycan structure that strengthens the division site in Escherichia coli.
doi.org
Super excited to launch this search for a new endowed professor at the @biozentrum.unibas.ch! Join us to build a research cluster in Climate Biophysics! 🌍🌊🌾🔬🧪 This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️ Questions? Please reach out! 👩🔬👨🔬
New Assistant (tenure-track) or Associate Professor position in Climate #Biophysics! Join our international research community to explore fundamental molecular mechanisms underlying climate-relevant biological processes. Apply by 7 Sept 2026! www.biozentrum.unibas.ch/de/open-posi...
New paper! 🚀 A high-affinity anti- #mNeonGreen #nanobody turns #mNG into a #multifunctional Tag. @nanotag.bsky.social decided to openly share the #nanobody for research use. Not common, but we strongly believe well-defined reagents are key for reproducible science. We hope you find it useful! 💚
Big news! 🎉 Huge congratulations to Dr. Virginie Hamel (@centriolelab.bsky.social) on being elected an @embo.org Member. We are so excited to host her as a speaker at #EMBOCilia2027 to discuss her group's incredible work uncovering the mechanisms of centriole and cilia assembly. 🔬✨ #cilia
Honored and delighted to be elected an EMBO Member. A huge thank you to our amazing team, this recognition wouldn't be possible without you. Perfect day to celebrate together during our lab outing! 🎉 - Virginie
Welcome and congratulations to the 60 new members and 11 associate members who have been elected to the EMBO Membership! They join a community of more than 2,200 leading scientists. 🧪 https://www.embo.org/press-releases/seventy-one-leading-scientists-elected-to-the-embo-membership/ #EMBOMembers2026
Welcome and congratulations to the 60 new members and 11 associate members who have been elected to the EMBO Membership! They join a community of more than 2,200 leading scientists. 🧪 https://www.embo.org/press-releases/seventy-one-leading-scientists-elected-to-the-embo-membership/ #EMBOMembers2026
🌟 Warmest congratulations to Virginie Hamel @centriolelab.bsky.social on being elected a Member of the @embo.org This prestigious lifelong distinction recognizes your outstanding excellence in the life sciences! #centriole #U-ExM @mocel.bsky.social @sciencesunige.bsky.social
Welcome and congratulations to the 60 new members and 11 associate members who have been elected to the EMBO Membership! They join a community of more than 2,200 leading scientists. 🧪 https://www.embo.org/press-releases/seventy-one-leading-scientists-elected-to-the-embo-membership/ #EMBOMembers2026
🆕 ADVANCE ONLINE 🆕 RESEARCH PAPER: CDK1 and CEP97 cooperatively control centriole length to orchestrate ciliogenesis and developmental patterning By Liu et al. and Jeremy Reiter ➡️ https://ow.ly/SOeZ50ZaaJo UCSF Helen Diller Family Comprehensive Cancer Center Chan Zuckerberg Biohub Network Biohub
Coupes drastiques du budget de la recherche + durcissement des règles d’attribution des financements ANR «Allez à l’ERC!» qu’ils disent, mais l’ERC saturée prend des mesures pour limiter les candidatures #deadend#recherchefrançaise Une petition semble vaine mais il faut commencer quelque part 👉
Un pétition du collège des sociétés savantes pour mettre en avant le rôle de la recherche dans la campagne politique à venir et rappeler le sous investissement chronique en France depuis 20 ans. N'hésitez pas à faire ciculer recherche-publique-2027.fr
We warmly congratulate Robbie #Loewith on receiving an @erc.europa.eu Advanced Grant 2025 : a well-deserved recognition of his exceptional research and scientific impact 👏 @mocel.bsky.social @sciencesunige.bsky.social www.unige.ch/recherche/en...
New preprint! In collaboration with the Steinmetz Lab at PSI we report cryo-EM structures of microtubules at up to 1.9 Å (!) resolution & in different nucleotide state mimics, suggesting a mechanism for lattice-induced GTP hydrolysis and why it leads to catastrophe: tinyurl.com/7cjrf863
Is there a size limit for cells ? How can cells replicate inside the architecture of their environment? Why do cells self-destroy ? This 15-minute movie vimeo.com/1173229237 shows our 2026 edition of the Living Architectures project at the @museeorsay.bsky.social
Excited to share our new preprint! 🧬❄️ by brilliant @mdreimann.bsky.social and great collaborators! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition #ArchaeaSky www.biorxiv.org/content/10.6...
🥉 Third Prize Winner! 🥉 Congrats to PhD student @anthonyrabate.bsky.social (Université Lyon 1) for this stunning shot, "A tulip field in the drosophila testis"! 🌷 These are young elongating spermatids captured via expansion microscopy. 🔬✨ #FluorescenceFriday #Cilia2027
The CNRS has opened a Junior Professor Chair (CPJ) call in Parasitology, and the Microbiologie Fondamentale et Pathogénicité (MFP, Bordeaux) laboratory is among the potential host institutions. More information: www.insb.cnrs.fr/fr/cnrsinfo/... #Parasitology #Protozoology #ResearchJobs #CNRS
Junior Professor Chairs (CPJ) 2026 – CNRS Biology
CNRS Biology is recruiting researchers through its Junior Professor Chair (CPJ) program, subject to final approval by the French Ministry of Higher Ed
insb.cnrs.fr
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...
📢 We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social! Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues — all in the heart of Paris.