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Scott_Boyd_Lab_Stanford

@scottboydlab.bsky.social

Scott Boyd Lab for Human Immunology Research at Stanford University.

10 Posts990 Follower1715 Folgt
Hensley Lab@scottehensley.bsky.social · last yr.

Anyone that has been around a lab knows that the trainees really drive the research, while most professors just sort of guide the ship. Most innovation comes from our trainees. Old professors like me will be able to survive these cuts, but our young scientists and our future will be destroyed.

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Max Kozlov@maxkozlov.bsky.social · last yr.

Researcher Amita Gupta has spent more than a decade planning and running a $70-million trial to study a new tuberculosis drug, enrolling ~6,000 participants in 13 countries. It might all have been for nothing. That's because a new NIH policy has abruptly cut off billions to trials abroad. 🧪

NIH grant cuts will axe clinical trials abroad — and could leave thousands without care

US agency’s new policy could abruptly end studies of infectious diseases and cancer, leaving researchers scrambling for funds.

nature.com

Hensley Lab@scottehensley.bsky.social · last yr.

Check out this news story that @nature.com wrote describing our recent preprint where we tested our H5 mRNA vaccine in calves. The data look good and we are currently testing the vaccine in lactating cattle...more to come!

Nature@nature.com · last yr.

As bird flu sweeps across US poultry and cattle farms, researchers are racing to find ways to contain the outbreaks before they ignite a human pandemic. Now, a team of scientists has developed a fresh approach: the first mRNA bird-flu vaccine for cattle. https://go.nature.com/4kbOvTe

Stephen Jacob Smith@stephenjacobsmith.com · last yr.

“This image from video posted on the Children's Health Defense [RFK Jr.’s anti-vax nonprofit] website on March 31 shows Dr. Ben Edwards with a measles rash on his face, while working in a makeshift clinic in Seminole, Texas.” www.cnn.com/2025/04/19/h...

Video shows doctor with measles treating kids. RFK Jr. later praised him as an ‘extraordinary’ healer | CNN

A Texas doctor who has been treating children in a measles outbreak was shown on video with a measles rash on his face in a clinic a week before Health Secretary Robert F. Kennedy Jr. met him and prai...

cnn.com

Sera Markoff@profsera.bsky.social · last yr.

I can’t exaggerate how badly this will affect our field, also internationally since many missions are jointly funded with eg ESA and JAXA. We are basically pinning our hopes on congressfolk to fight for all the regions that will lose jobs, since the science isn’t winning any arguments. 😢🔭🧪

Dr. Jessie Christiansen@aussiastronomer.bsky.social · last yr.

First the rumour was a 20% budget cut. Then, 50%. Now the president's NASA budget is out and it's a 68% cut to astrophysics ($1.5B to $487M). Even if this gets reversed in four years, we will *never* recover the missions, partners, people who will be gone. www.washingtonpost.com/science/2025...

Scott_Boyd_Lab_Stanford@scottboydlab.bsky.social · last yr.

Many outstanding medical researchers at NIH threatened by non-renewal of contracts: www.science.org/content/arti... They give the US new discoveries & the economic benefits of doing the risky first steps toward innovative cures. Harming medical research is a self-inflicted national injury.

NIH ban on renewing senior scientists adds to assaults on its in-house research

Policy follows firings of tenure-track scientists and suspension of training programs

science.org

@tibshirani.bsky.social · last yr.

I am happy to announce our new paper "Univariate-guided sparse regression". It's a new lasso that leverages the signs and magnitude of univariate coefficients . Sparser and more interpretable than the lasso. We're excited! arxiv.org/abs/2501.18360 R: github.com/trevorhastie...

Univariate-Guided Sparse Regression

In this paper, we introduce ``UniLasso'' -- a novel statistical method for sparse regression. This two-stage approach preserves the signs of the univariate coefficients and leverages their magnitude. ...

arxiv.org

Marion Pepper@marionpepper.bsky.social · last yr.

This is heartbreaking. But not an unfamiliar feeling for my science colleagues and my own lab who burnt the midnight oil 24/7 studying COVID immunity to understand how to protect American lives during the pandemic. Nonsensical, performative betrayal. No one will actually benefit and people will die.

Senator Patty Murray@murray.senate.gov · last yr.

Gregg is a former Marine and Forest Service ranger. He's saved the lives of hikers dangling off a cliff or going through cardiac arrest, and he's bravely fought forest fires to save small rural towns. 100% of his salary is paid by WA state. Elon fired him. Share his story.

Scott_Boyd_Lab_Stanford@scottboydlab.bsky.social · last yr.

Destructive, cruel and directly harmful to the health and security of America. The physical, real world of viruses and other pathogens doesn’t care about politics and won’t spare us.

Lewis Kamb@lewiskamb.bsky.social · last yr.

CDC source: “We just had word that all our fellows and post doc staff are laid off effective immediately. The famous Epidemic Intelligence Service, aka the Disease Detectives, is no more. That’s 1260 staff. They are calling this ‘Phase 1’.”

Fyodor Urnov@urnov.bsky.social · last yr.

NIH-supported research saves lives: here are two "poster" human beings to prove it. Emily Whitehead: cured of her leukemia by CAR-T developed at Penn. Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.

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Kathleen Clark@kathleenclark.bsky.social · last yr.

The 22 state AGs note that in 2017, Trump proposed a similar across-the-board rate cut, but Congress rejected it. In 2018 & every year since, Congress has enacted an appropriations rider forbidding NIH from pursuing an across-the-board rate cut.

Case 1:25-cv-10338 Document 1 Filed 02/10/25 Page 4 of 59 6. In 2017, during his first administration, President Trump made a budget proposal that would have reduced the indirect cost rate for research institutions to an across-the-board, categorical rate of 10%. Congress unequivocally responded to ward off such a change to the calculation of indirect cost rates. In 2018, Congress enacted an appropriations rider prohibiting HHS or NIH from spending appropriated funds "to develop or implement a modified approach to" the reimbursement of "indirect costs" and "deviations from negotiated rates." Consolidated Appropriations Act, 2018, Pub. L. No. 115-141, 132 Stat 348, § 226. That rider has remained in effect through every appropriations law governing HHS to this day. See Further Consolidated Appropriations Act, 2024, Pub. L. No. 118-47, § 224. 7. On February 7, 2025, NIH nonetheless issued a guidance document pronouncing that all indirect cost rates for NIH grants would be reduced to 15%, in Notice Number NOT- OD-25-068, Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates (the "Rate Change Notice"). This reduction applies not only to new grants but to existing grants, and becomes effective on February 10, 2025, just one business day after the Rate Change Notice issued.
Josh Barocas, MD ⭕️@jabarocas.bsky.social · 2y ago

Why should the public care about the freeze on the NIH? Aside from the need for scientific pursuits to make our society better… -For every dollar we invest in NIH research, there is a $2.5 return. -Research dollars help fund universities that employ non-academics. (1/)

Angie Rasmussen@angierasmussen.bsky.social · 2y ago

My replies are perpetually full of anti-vaxxers these days telling me about polio vaccines. Not shockingly, most of what they are saying is wrong. Luckily, I trained with Vincent Racaniello & he taught me a few things about poliovirus. So let’s discuss the king of the Picornaviridae👇🏻

Picture of a plaque assay (purple field with clear holes) showing gorgeous poliovirus plaques
Scott_Boyd_Lab_Stanford@scottboydlab.bsky.social · 2y ago

A remarkable story from @mfgrp.bsky.social and colleagues: immunization via skin S. epidermidis generates systemic and mucosal antibody responses.

Michael Fischbach@mfgrp.bsky.social · 2y ago

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55