Why do our cells age? It's not just wear and tear, accumulated damage. Loss of cell identity takes center stage. A new Nature paper and connection with prior work that substantially advances the science of aging. In the new Ground Truths. erictopol.substack.com/p/loss-of-ce...
Loss of Cell Identity Drives Human Aging
That’s What Biological (Epigenetic) Aging Clocks Are Measuring
erictopol.substack.com
You should always say "yes" to a quick 30 minute paddle. That hour and a half could be the best 4 hours of your life.
Are you tired of having to double take everything you see online because it might be fake AI slop? Get ready to double take your own photos because they may be fake AI slop.
with apologies to the young man who left his extremely well-curated spotify account logged in on the hotel tv: if my daughter didn’t hear elmo’s alphabet rap we were all going to die
While I nodded, merely napping, suddenly there came a scatting, Like some jazz man crazy catting, scatting at my chamber door. Quoth Jazz Raven, 'SKABBADA BAP BAP BWIDDILY BAP BAP DIBBETY BEEP BAP BEE DOODLEOO'
Astonishing video of a freight train's crew, stopped in the midst of a raging wildfire near Armstrong, Ontario, in order to let another oncoming train pass: www.instagram.com/reel/DaymbMr...
They tell me I’m uncultured, but I’ll always recognise a bit of Beethoven.
I'll summarize this: Mamdani asked NYers to keep air conditioning at 78 degrees. A wave criticism hit online. A MSNBC broadcast pointed out the US Department of Energy recommends that 78 degree figure. Immediately after, the US Department of Energy deleted 6,000 web pages related to energy saving.
💥 In Donetsk region, birds are building nests from drone fiber optics.
Some closeups of the Hair Keyboard, because Fuck You.
Yes, Swiss scientist Fritz Zwicky coined the term “dark matter” which is impressive, but he also coined the term “spherical bastard” to describe people who are bastards no matter which way you look at them, and I think that should be celebrated more.
i read this and it's interesting but the horrifying overhang of this story is "mrna vaccines make it relatively easy to cure cancer actually, and the main obstacle is that the FDA just banned trials of them"
Mrs. Reach / Mrs. Curio@reachartwork.bsky.social · 7mo agowww.theaustralian.com.au/business/tec... hey. hold on. what the fuck??? (/pos)
I'm sorry the guy changing the rules on the fly is named what
Governor Wes Moore@govwesmoore.bsky.social · 8mo agoI stand with County Executive Calvin Ball as he signs emergency legislation today prohibiting privately owned buildings from being used as ICE detention centers. Howard County chose dignity, accountability, and its people. Tune into our event now: bit.ly/4a2VtHw
Hilariously, a coyote walked behind a San Francisco reporter as she was doing a segment on the mountain lion. 🤣
Even with everything else going on, this still sounds like a dark joke.
Trump’s E.P.A. Has Put a Value on Human Life: Zero Dollars
nytimes.com
GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.
Anyone using this should lose their license. bsky.app/profile/davi...
The diagram for what Palantir does is like if Richard Scarry got super paranoid and did an Apocalypse picture book
![Conversation
Crémieux
@cremieuxrecueil
·
Feb 15, 2025
DOGE has a very obvious feedback mechanism for its cuts.
If DOGE makes a big, broad cut against a million programs, people get upset about a few specific, very good ones like PEPFAR, and then that program comes back because DOGE's members are, thus, informed it was good.
Crémieux
@cremieuxrecueil
·
Feb 15, 2025
I can only hope people realizing this won't damage the mechanism, because it's still useful to have professionals getting mad about some very good thing getting cut before it's brought back online as a result.
In a word, DOGE is responsive, which is unusual for the government!
Stuart Buck
@stuartbuck1
·
Feb 15, 2025
I agree, but it would be more efficient to spend one hour ahead of time talking to experts or just reading up on the history of a program for [disease, student testing, nuclear safety, etc.]
Plus, some programs don't have famous proponents with time to dig into the weeds.
Crémieux
@cremieuxrecueil
·
Feb 15, 2025
I'm highly sympathetic, but there really are thousands and thousands of programs and grants to cut, so I'm not sure the small team doing the cuts has the ability to go through them all one-by-one on their short timeline.
Maybe a system can be developed to assist with feedback.
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Stuart Buck
@stuartbuck1
Despite some bogus grants, a lot of government is like this cartoon. I bet this "small team" would find a line item for "screwworm sterilization" and delete it, not knowing that they just devastated American farming: https://theatlantic.com/science/archiv
e/2020/05/flesh-eating-worms-disease-containment-america-panama/611026/
Image
5:03 PM · Feb 15, 2025
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Sky Marchini
Stuart Buck
@stuartbuck1
·
Feb 15, 2025
I can see the DOGE tweet: "We canceled a contract for Panamanian screwworms, saving $165 million dollars!!!" [https://aphis.usda.gov/news/agency-an
nouncements/usda-approves-emergency-funding-protect-us…](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:j2kmiyhld5btzozgzwy3lc2m/bafkreih3ferjvpo53fmioc3sf2qadxltbmisl74luq2ydhxvpxbh3qf3ei)
