Stephen Kissler

@skissler.bsky.social

Infectious disease epidemiologist / computer science professor @ CU Boulder. Trying to figure out how to keep us all healthy and fed.

I'm excited to share a preprint that's been years in the making: the idea took shape during the COVID pandemic. Anecdotally, people would sometimes spread COVID at work but not at home, and vice versa. Why? One explanation would be if infectiousness is fleeting...

How bursty infectiousness shapes epidemic dynamics

An epidemic’s expected course is determined by the magnitude and timing of a typical person’s infectiousness — captured, in turn, by the basic reproduction number and the generation-time distribution....

medrxiv.org

In 2017, while working at Epicentre/Medecins Sans Frontieres I helped to develop the Urgepi program in southeast DRC. What started as measles surveillance program has matured into a prioritization scheme for outbreak prevention and response that serves 15m people (land area ~Spain).

Risk-targeted interventions for measles control- Lessons from an emergency response project in the Katanga Region, Democratic Republic of the Congo (2021-2023)

The Urgepi project is a measles emergency initiative implemented by Medecins Sans Frontieres Operational Centre Paris (MSF-OCP) in the Katanga region of the Democratic Republic of Congo, a setting cha...

medrxiv.org

This is a *fantastic* video that explains exactly WTF is going on with Taylor Farms and how tracing works TLDR: - they are responsible - the false positive was only on one of several samples - it’s difficult to test parasites - there may still be other sources - Taylor Farms is being shady AF

Throughout your scientific career, you will read hundreds of dense manuscripts. 📚 As the literature stack piles up, remembering exactly where you saw a specific methodology or finding can be tough. Here is how I use a relational database to keep track of it all (and et al.). 👇

NIH grants have been under political scrutiny since early 2025. But what does the screening process actually look like? What is being flagged? I spent a month digging into leaked docs and emails. We've published the 235-word list that are being flagged by an internal AI tool. And so much more. 🧵

Inside the new political screening that’s stalling NIH grants

Mandatory reviews by top health officials and checks for 235 disfavoured terms have left hundreds of vetted grant applications in administrative limbo.

nature.com

A year before he passed away, I interviewed Dr Paul Farmer @pih.org about his book on Ebola So relevant right now, especially the dangers of “control-over-care approach” - i.e. isolation & quarantine, but fails to ensure adequate clinical care to the sick www.forbes.com/sites/madhuk...

Ebola, Covid-19 And The Elusive Quest For Global Health Equity

Published during this pandemic, Paul Farmer’s new book, “Fevers, Feuds, And Diamonds,” is important, as it presents a critical dissection of the Ebola outbreak in West Africa, and the lessons we can l...

forbes.com

🚨 Disease modelers: Do you use empirical VE estimates interchangeably to inform vaccine effect parameters? Me too, and it’s distorting our predictions. VE estimates often do not align with model parameters. We discuss these pitfalls & solutions in our new preprint: arxiv.org/abs/2605.18571 🧵👇

Incorporating vaccine effects into epidemiological models: common pitfalls and solutions

Incorporating vaccination into mathematical models appears deceptively simple: models integrate vaccine-derived protections, such as reduced susceptibility to infection, using parameters informed by e...

arxiv.org

1. #WHO has declared the #Ebola #Bundibugyo outbreak in NE DRC a public health emergency of international concern, aka a PHEIC. Yet another sign this is likely to be a very challenging outbreak. So far there've been 8 confirmed cases, 246 suspected cases & 80 suspected deaths.

Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern

Pursuant to paragraph 2 of Article 12 - Determination of a public health emergency of international concern, including a pandemic emergency of the International Health Regulations (2005) (IHR), the Di...

who.int

WHO@who.int · 3mo ago

Under the IHR (2005), @drtedros.who.int, the Director General of WHO, having consulted the States Parties where the event is occurring, has determined that the Ebola disease caused by Bundibugyo virus in DRC & Uganda constitutes a public health emergency of international concern bit.ly/3P4ZDac

Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern

Sooooo... Several people shared this slide with me. NIH is apparently working on a new parent mechanism called an RP1. I have many questions (and only a few answers). (EPMC is the NIH-wide Extramural Program Management Committee co-chaired by Jon Lorsch). 1/4

A slide from the NIH Extramural Program Management Committee about a new "RP1 Mechanism" labelled as a "Science-Driven Research Project"

The #hantavirus outbreak on the cruise ship off the coast of Africa is a serious public health event that needs to be handled properly. But if you are having #Covid flashbacks, put those worries to rest. The risk here is to people on the ship & their close contacts. www.statnews.com/2026/05/07/h...

Cruise ship hantavirus outbreak worries experts, though they discount pandemic fears

Scientists are worried that hantaviruses haven’t been as well studied as they ought to be, but not that the MV Hondius cruise ship is ground zero for the next pandemic.

statnews.com

A few additional key details 👇, building on what I mentioned yesterday - human-to-human transmission on-board is the most likely explanation, but, importantly, does not mean this is likely to cause a larger outbreak. The ship’s doctor among suspected cases + reportedly, no rodents on board.

Kai Kupferschmidt@kakape.bsky.social · 3mo ago

I've spent yesterday and today talking to researchers across the globe trying to understand the hantavirus outbreak aboard the cruise ship MV Hondius. My story in @science.org is here (and some threaded thoughts coming): www.science.org/content/arti... 🧪 #IDsky

My #atscience talk about Lea is now online! If you've only ever heard me talk about NLP, here's a chance to hear me rant about #atproto (the protocol you're reading this on!), social media for researchers, and the free internet. And if you're interested in helping us build Lea, please reach out!

Lea: A Social App for Researchers - ATmosphereConf 2026

YouTube video by AT Protocol Development, Tech Talks, and Events

youtube.com

Maria Antoniak@mariaa.bsky.social · 4mo ago

I'll be at #atscience #atmosphereconf all day today! I'll be speaking at 10:15AM about Lea, a social app for researchers, plus a panel at 2PM. Please say hi and chat with me about online communities, AI/ML/NLP, custom feeds, verification, labelers, "community notes," scifi books and movies, etc.