Don’t miss 2026 Edward Novitski Prize recipient Michael O’Connor on August 11 to learn how a 30-year quest to understand the shrew gene is shedding new light on Drosophila embryonic development. 🔗https://buff.ly/uvGHncW

BMP10 KO alone, but not BMP9 KO alone, induces #ArterioVenousMalformation in 🐭Retina Brain wounded Skin ROSA26-CreER; Bmp10 f/f vs Bmp9-/- vs compound KO B6/129 strain Exogenous BMP10, not BMP9, rescues retinal vascularization in BMP9/10 dKO🐭 #Angiogenesis 2023 link.springer.com/article/10.1...

We are excited to share our latest publication in JBC, which elucidates the role of heparan sulfate in erythroferrone-mediated BMP inhibition! Check out our findings here: www.jbc.org/article/S002...

Erythroferrone antagonism of BMPs is governed by a composite heparin-binding motif

Iron homeostasis is regulated by bone morphogenetic protein (BMP) signaling, which induces hepcidin to negatively regulate serum iron levels and iron import. After a major blood loss event, developing...

jbc.org

Our method optimization study is out in Cytometry Part B: Clinical Cytometry🎉! Choice of wash buffers is important to avoid cell loss for diagnostic flow cytometry sample types! We hope this is useful to other laboratories doing clinical flow cytometry! onlinelibrary.wiley.com/doi/10.1002/...

Effects of washing procedures on cell loss in different diagnostic flow cytometry sample types

Click on the article title to read more.

onlinelibrary.wiley.com

Today’s #Bluesky with natural reflecting pool #Norway #Kjerringøy

Advertise your Bluesky account with a Simpsons GIF

Lisa Simpson Shrugs in The Simpsons

Alt: Lisa Simpson Shrugs in The Simpsons

static.klipy.com

Talquetamab–daratumumab, with or without pomalidomide, led to longer progression-free survival than daratumumab-based standard care in relapsed or refractory myeloma. More than 75% of patients had grade 3 or higher adverse events. Full MonumenTAL-3 trial results: https://nej.md/4ojBcCL #EHA2026

Nature Comms is seeking an editor with expertise in clinical infectious diseases urldefense.com/v3/__https:/...

Interested in TGF-β family signaling? Then you should join us for the upcoming FASEB conference #TGFbSRC

FASEB@faseborg.bsky.social · 3mo ago

For 25+ years #TGFbSRC has united researchers of a critical signaling pathway. This conference gathers academic and industry leaders plus early-career investigators to discuss the latest TGF‑β family signaling. Extended abstract & early registration deadline: June 14.

Still time to register & submit your abstract for a potential short talk! The FASEB TGF-β family in Development and Disease conference in Porto, July 26.-30. coming up. Early registration and extended abstract submission deadline is June 14th 👇 @mythreye.bsky.social events.faseb.org/event/TGF-B/...

Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact Thermo Fisher Scientific has systematically manipulated antibody validation data!

Exciting PhD vacancy in my lab at Amsterdam UMC! 4-year, fully funded KWF project studying cell-cell communication in the myeloma bone marrow niche and drug resistance. Feel free to share! More info: werkenbij.amsterdamumc.org/en/vacatures... #PhD #Myeloma #KWF @amsterdamumc.bsky.social

Vacatures - PhD hematology/oncology: bone marrow microenvironment in multiple myeloma - Amsterdam UMC

Explore how the bone marrow microenvironment drives therapy resistance in multiple myeloma. Develop innovative 3D models and single‑cell analyses in a dynamic research team at Amsterdam UMC.

werkenbij.amsterdamumc.org

Great review on MGUS!

Vincent Rajkumar, MD@vincentrk.bsky.social · 10mo ago

Our comprehensive Review on MGUS: Monoclonal Gammopathy of Undetermined Significance @NEJM 5% of people over age 50 have MGUS. Every physician needs to know and understand MGUS. Lots of Tables and Figures. www.nejm.org/doi/abs/10.1...

Free and open-source images, icons, and tools for creating scientific illustrations doi.org/10.59350/5zt... 🧪

Free and open-source images, icons, and tools for creating scientific illustrations

Phylopic, NIH Bioart, Bioicons, Scidraw, Open Science Art, Health Icons, Servier Medical Art, Biodiversity Heritage Library, the Noun Project, Segment Anything, Excalidraw, draw.io, Biographics

doi.org

Join us for the FASEB Science Research conference on TGF-β Family in Development and Disease! Awards Abstract Submission Deadline: April 15, 2026. @faseborg.bsky.social @mythreye.bsky.social

Toril Holien@torilhol.bsky.social · 5mo ago

Registration is open 😀! Make a note of these dates: Awards Abstract Submission Deadline: April 15, 2026 Regular Abstract Submission Deadline: May 31, 2026 Early Registration Deadline: June 14, 2026 events.faseb.org/event/TGF-B/...

Activin A secretion by muscle-repairing macrophages induces heterotopic ossification in mice @jci.org www.jci.org/articles/vie...

Excited to announce the opening of the applications for the Master in Biomedical Research. An international, hands-on programme for students to think like scientists, work in real labs, and prepare for PhD training or R&D careers, in Lisbon. GIMM Institute 1/3

Registration is open 😀! Make a note of these dates: Awards Abstract Submission Deadline: April 15, 2026 Regular Abstract Submission Deadline: May 31, 2026 Early Registration Deadline: June 14, 2026 events.faseb.org/event/TGF-B/...

Check out the line-up for the @faseborg.bsky.social Science Research Conference on TGF-β Family in Development and Disease 👇 events.faseb.org/event/TGF-B/...

Check out the global speaker line up. several travel awards and slots for short talks open. Don’t miss this summer @faseborg.bsky.social events.faseb.org/event/TGF-B/...

Toril Holien@torilhol.bsky.social · 12mo ago

📣 Save the date 📣 The next FASEB Science Research Conference on TGF-β Family in Development and Disease will take place: July 26-30, 2026 in Porto, Portugal! @faseborg.bsky.social With Mythreye Karthikeyan @mythreye.bsky.social, Rosemary Akhurst and Andrew Hinck web.cvent.com/event/af5f6d...

Decoding the Mechanism of Action of a Parasite TGFβAntagonist Inspires the Creation of Cell-type-specific TGFβ Modulators https://www.biorxiv.org/content/10.64898/2026.02.16.706112v1

Cow Tools! We have lived alongside cows for nearly 10,000 years. We breed them and exploit them It is now, only now, that we have discovered THEY CAN USE TOOLS Here I describe our study (paper) www.sciencedirect.com/science/arti... in @currentbiology.bsky.social with @auersperga.bsky.social

😂

Eric Feigl-Ding@drericding.bsky.social · 7mo ago

📺 OMG—who made this?! Noah Wyle has a message for all you—vaccine skeptics… Share with a friend who needs to hear it.

Hyperactive BMP and Mechanosignaling Remodel Chromatin to Drive Aberrant Osteogenesis in FOP https://www.biorxiv.org/content/10.64898/2026.01.05.697733v1

Discovery and Characterization of Zilurgisertib, a Potent and Selective Inhibitor of Activin Receptor-like Kinase‑2(ALK2) for the Treatment of Fibrodysplasia Ossificans Progressiva. T Ullrichet al. ACSMed.Chem. Lett. 31Oct 2025 shorturl.at/UCzDT …mouse model …start clinical trial

🚨 New paper out! A human epiblast model reveals how dynamic TGF‑β signalling controls epithelial identity in early mammalian development Here is the full paper: rdcu.be/eSWEs 🧵 A twittorial: THREAD

A human epiblast model reveals dynamic TGFβ-mediated control of epithelial identity during mammalian epiblast development

Nature Cell Biology - The authors optimize an in vitro human epiblast model, which they utilize to show that early TGFβ family inhibition prevents epithelial identity, whereas it is...

rdcu.be

Researchers report knockdown of Activin receptor-like kinase 5 (ALK5) & Mothers against decapentaplegic homolog 2 (SMAD2) - 2 genes of the TGFb pathway, protected dopaminergic neurons from a-Synuclein-induced toxicity; ⬆️TGFb signaling exacerbated a-Synuclein toxicity www.nature.com/articles/s41...

C'mon guys. Cells show blebbing and death was inhibited by caspase inhibitors and had mitochondrial permeabilization. In my alternate universe, this is apoptosis 🙄

Christian Frezza@frezzalab.bsky.social · 9mo ago

Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia: Cell www.cell.com/cell/fulltex...

🧬 Kinase Inhibitors can do more than block their targets! A study by @cemm.oeaw.ac.at-@aithyra.bsky.social and #IRBBarcelona reveals that many inhibitors also trigger the degradation of the kinases, uncovering an overlooked mechanism with therapeutic potential. Out in @nature.com ➡️ bit.ly/43SD9xj

European Respiratory Journal: The activin signalling inhibitor sotatercept may transform PAH therapy by targeting pulmonary vascular remodelling, but unique safety risks demand careful monitoring https://bit.ly/3UBsPVj